Dipalmitoylethyl Dimonium Chloride: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Dipalmitoylethyl Dimonium Chloride?

Dipalmitoylethyl Dimonium Chloride is a quaternary ammonium compound made by reacting palmitic acid, a fatty acid found in palm oil and other plant fats, with an amine then quaternizing the result with chloride. This process links two palmitic acid chains to a nitrogen center, giving a molecule that loves both oil and water which is useful in personal care products. First introduced in hair care formulas in the late twentieth century, it quickly became popular as a safer, milder alternative to older conditioning agents. Today manufacturers produce it in large batches by combining purified palmitic acid with ethanolamine, followed by controlled chemical steps under heat and vacuum to form the finished chloride salt.

You will most often see Dipalmitoylethyl Dimonium Chloride in rinse off and leave in hair conditioners, masks, detangling sprays, anti frizz serums and some intensive repair treatments for damaged hair. It may also appear in a few cream cleansers and two in one shampoos where extra softness is desired.

Dipalmitoylethyl Dimonium Chloride’s Cosmetic Benefits/Uses

In formulas this ingredient serves two key roles that translate into noticeable hair benefits.

  • Antistatic: Helps neutralize the electrical charge that builds up on hair strands during washing or styling which cuts back on flyaways and makes hair easier to manage
  • Hair conditioning: Forms a thin, smooth layer over the cuticle increasing softness, slip and shine while also aiding detangling and reducing breakage from combing

Who Can Use Dipalmitoylethyl Dimonium Chloride

This conditioning agent is generally suitable for all hair and skin types including oily, dry and sensitive scalps because it rinses clean and leaves only a light conditioning film. Those with very fine or low porosity hair might find that heavy concentrations weigh strands down so lighter leave-in formulas may be preferable.

Dipalmitoylethyl Dimonium Chloride is typically produced from plant-derived palmitic acid and synthetic processing aids so it is usually acceptable to vegans and vegetarians. If the label specifies that the ingredient is sourced from palm oil certified by sustainable bodies this can give additional peace of mind.

Current safety data show no known risks for pregnant or breastfeeding women when the ingredient is used topically at the low levels found in cosmetics. This is not medical advice and anyone who is pregnant or nursing should review all personal care products with a qualified health professional to be sure they meet individual needs.

The ingredient does not increase photosensitivity, meaning it will not make skin or hair more prone to sun damage. It is also non-volatile so it poses minimal inhalation risk during normal consumer use. People with a known allergy to quaternary ammonium compounds should nonetheless read labels closely before use.

Potential Side Effects/Adverse Reactions

Reactions to Dipalmitoylethyl Dimonium Chloride vary from person to person. The following list covers potential side effects, but most users will not experience them when the ingredient is correctly formulated and used as directed.

  • Mild scalp or skin irritation such as redness stinging or itching, usually in individuals with very sensitive skin
  • Allergic contact dermatitis resulting in localized rash or hives in people allergic to quaternary ammonium compounds
  • Eye irritation if the product accidentally gets into the eyes during application or rinsing
  • Product buildup leaving hair feeling greasy or weighed down when high concentrations are used on fine or low porosity strands

Discontinue use and consult a healthcare professional if any negative reaction occurs while using a product that contains Dipalmitoylethyl Dimonium Chloride.

Comedogenic Rating

Rating: 1 / 5

Dipalmitoylethyl Dimonium Chloride is a large, positively charged molecule that stays mainly on the surface of hair and skin instead of sinking into pores. It also tends to be used in rinse-off or light leave-in products, so the chance of it clogging pores is very low. Because of this it earns a rating of 1 rather than a perfect 0, as heavy leave-ins or scalp treatments could still trap oils if overused.

Overall it is considered suitable for people who are prone to acne or breakouts.

If you use other rich, oil-based products alongside it keep an eye on how your skin responds since buildup from multiple ingredients can change the overall pore-clogging potential.

Summary

Dipalmitoylethyl Dimonium Chloride acts as an antistatic and hair-conditioning agent. Its double palmitic acid tails coat the hair cuticle while the quaternary nitrogen carries a positive charge that binds to the negatively charged hair surface. This reduces static, smooths rough spots, boosts shine and makes detangling easier so breakage is less likely.

The ingredient is fairly popular in modern conditioners and masks because it gives a silky feel without the heavy, greasy touch some older quats leave behind. You will mainly spot it in mid-priced to premium hair care lines while mass-market brands still rely on longer-standing conditioning agents.

Current research shows it to be safe for topical use at the concentrations found in cosmetics with only rare reports of irritation or allergy. As with any new product it is smart to do a small patch test first to be sure your skin or scalp agrees with it.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search