Dipentaerythrityl Tetraisostearate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Dipentaerythrityl Tetraisostearate?

Dipentaerythrityl Tetraisostearate is a specialty ester created by joining isostearic acid, a fatty acid that comes from vegetable oils, with a dimer of pentaerythritol, a sugar-derived alcohol. The result is a large, oil-rich molecule that feels silky yet non-greasy on skin.

The rise of this ingredient dates back to the late 1990s when formulators began looking for plant-based alternatives to mineral oil that could leave a light finish. Chemists discovered that linking pentaerythritol to isostearic acid produced an emollient that spread easily, resisted oxidation and blended well with both oils and waxes. Since then it has become a go-to texture enhancer in many modern formulas.

Manufacturing starts with sustainably sourced vegetable oil, which is split to obtain isostearic acid. This acid is then reacted with pentaerythritol under heat and a catalyst, forming a tetraester. After purification the finished material appears as a clear to pale-yellow liquid that stays stable even at high temperatures.

Dipentaerythrityl Tetraisostearate is widely used in color cosmetics such as foundations, lipsticks and cream blushes because it improves glide and pigment dispersion. It also shows up in moisturizers, cleansing balms, sunscreen sticks, solid perfumes and anti-aging serums where a cushiony skin feel is desired.

Dipentaerythrityl Tetraisostearate’s Cosmetic Benefits/Uses

This multitasking ester earns its place in formulas thanks to two key functions

  • Skin conditioning – forms a soft film that helps keep water from escaping, leaving skin smooth and comfortable. It can also reduce the look of dry patches and improve overall suppleness
  • Emollient – fills in tiny gaps between skin cells creating an instant soft touch. Its light texture adds slip to creams, sticks and makeup, making application effortless without a heavy or oily residue

Who Can Use Dipentaerythrityl Tetraisostearate

This silky ester suits most skin types, especially normal, dry and mature skin that crave extra softness. Combination and mildly oily skin often tolerate it well thanks to its light slip, though very acne-prone users might find it a touch occlusive if layered heavily.

The raw material is derived from vegetable oils and contains no animal by-products, making it appropriate for vegans and vegetarians.

No data suggest any risk for women who are pregnant or breastfeeding when the ingredient is applied topically. Still, this is not medical advice and anyone expecting or nursing should ask a healthcare professional before adding new skincare to their routine.

Dipentaerythrityl Tetraisostearate does not cause photosensitivity, so daytime use is fine without extra sun precautions beyond normal sunscreen habits. It is also fragrance free and non-volatile, so it rarely triggers scent sensitivity or eye irritation.

Potential Side Effects/Adverse Reactions

Reactions to topical Dipentaerythrityl Tetraisostearate differ from person to person. The issues below are possible yet uncommon when the ingredient is used in a properly formulated product.

  • Clogged pores or breakout flare-ups in individuals with very oily or congestion-prone skin
  • Mild stinging or redness in people with heightened sensitivity to fatty esters
  • Rare allergic contact dermatitis presenting as itching or small rash patches

If any of these effects occur discontinue use and seek medical advice if symptoms persist or worsen.

Comedogenic Rating

Rating: 2/5. Laboratory and anecdotal data suggest Dipentaerythrityl Tetraisostearate sits on the lower end of the clogging scale. Its bulky ester structure does not penetrate pores as readily as smaller fatty acids, yet it still forms an occlusive film that can trap debris in very oily or congested skin. Most users with normal to slightly oily skin experience no pore blockage, while those highly prone to breakouts should monitor their skin when using products rich in this ester.

Overall it is generally suitable for acne-prone individuals, but caution is advised if your skin reacts quickly to richer emollients.

Formula context matters: when paired with lightweight silicones or volatile oils its pore-clogging potential drops, whereas thick balms or heavy stick foundations can push it closer to the upper end of the scale.

Summary

Dipentaerythrityl Tetraisostearate works mainly as a skin-conditioning emollient. By filling microscopic gaps between skin cells it smooths texture, locks in moisture and gives creams and makeup a velvety glide. Its high molecular weight also helps pigments disperse evenly so colors look vibrant and wear longer.

While not as famous as jojoba or shea butter, this plant-derived ester has quietly become a formulator favorite in modern foundations, lipsticks and solid sunscreens because it offers a light touch without relying on mineral oil.

Safety records are strong: it shows very low irritation, no phototoxicity and minimal allergen potential. Still, every skin is unique so it is wise to patch test any new product containing this ingredient before full application.

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