What Is Dipeptide-24?
Dipeptide-24 is a lab made peptide formed by linking two naturally occurring amino acids, glutamic acid and threonine. This tiny chain is designed to imitate fragments of larger skin proteins that play a role in keeping skin firm and smooth. Researchers first explored short peptides like this in the early 2000s when the beauty industry began looking for gentler alternatives to strong actives such as retinoids. By tweaking amino acid sequences scientists discovered they could encourage the skin’s own renewal signals without causing much irritation, and Dipeptide-24 was one of the results.
Production starts with individual amino acids that are chemically joined in a controlled setting called solid phase peptide synthesis. The finished peptide is then purified, dried into a fine powder, and blended into water based or emulsion formulas. You will most often see Dipeptide-24 in serums, eye creams, sheet masks, and premium moisturizers aimed at smoothing texture or softening fine lines. Because it pairs well with hydrating agents, brands also add it to overnight creams and leave-on treatments that promise a revitalized look by morning.
Dipeptide-24’s Cosmetic Benefits/Uses
Dipeptide-24 serves one main purpose in skincare formulas and that is to condition the skin. By acting as a conditioning agent it helps the surface feel softer, look more even, and maintain a healthy moisture balance. Regular use can support a refreshed appearance which is why the peptide shows up in products that focus on youthful looking skin.
Who Can Use Dipeptide-24
Dipeptide-24 is gentle enough for most skin types including dry, normal, combination and oily skin. Sensitive skin users usually tolerate it well because peptides are small and tend not to disrupt the skin barrier. Those with very reactive or allergy-prone skin should still check the full ingredient list of any product, as irritation is more likely to come from preservatives or fragrance rather than the peptide itself.
Because Dipeptide-24 is made entirely in a lab from basic amino acids it contains no animal-derived material, making it suitable for vegans and vegetarians.
Current data shows no specific risks for pregnant or breastfeeding women when Dipeptide-24 is applied topically. This is not medical advice and anyone who is pregnant or nursing should ask a healthcare professional before adding new skincare products to their routine just to be safe.
The peptide does not make skin more prone to sunburn and can be used day or night without raising photosensitivity. It also layers well with common actives such as niacinamide or hyaluronic acid, so it can slot into most routines without issue.
Potential Side Effects/Adverse Reactions
Responses to topical Dipeptide-24 differ from person to person. The points below outline possible effects yet they are uncommon when the ingredient is used at standard cosmetic levels and formulated correctly.
- Mild redness or warmth – a small number of users may notice temporary flushing that fades once the product is rinsed or usage is reduced
- Itching – light itchiness can occur, often due to other formula components rather than the peptide itself
- Stinging on compromised skin – freshly exfoliated or broken skin may feel a brief sting when the product is first applied
- Contact dermatitis – rare allergic reactions are possible in very sensitive individuals leading to rash or swelling
If any of these issues appear discontinue use and seek guidance from a medical professional.
Comedogenic Rating
Rating: 0/5. Dipeptide-24 is a tiny water soluble molecule that does not form an occlusive film or leave heavy residue on the skin, so it has virtually no tendency to clog pores. It is therefore suitable for people who are prone to acne or breakouts. Any chance of congestion would come from richer oils or butters in the overall formula rather than from the peptide itself.
Summary
Dipeptide-24 is a lab created two–amino-acid peptide that conditions the skin by signaling it to look smoother and feel softer while supporting moisture balance. It is not yet a household name but it appears in a growing number of mid to high tier serums and creams aimed at a youthful finish because it layers well with hydrating ingredients and causes little irritation.
Current research and real-world use suggest it is very safe for most skin types with a negligible risk of side effects when used in standard cosmetic concentrations. As with any new skincare ingredient it is smart to do a quick patch test before full use to make sure your skin agrees with the overall formula.