What Is Dipeptide Diaminobutyroyl Benzylamide Diacetate Oligopeptide-133?
Dipeptide Diaminobutyroyl Benzylamide Diacetate Oligopeptide-133 is a lab made peptide blend created by bonding two smaller peptide ingredients, Dipeptide Diaminobutyroyl Benzylamide Diacetate and Oligopeptide-133. Peptides are short chains of amino acids, the building blocks of proteins, and this particular pairing is designed to mimic the skin friendly portions of natural proteins while remaining stable and easy to formulate with. Both components are produced through controlled fermentation and solid phase peptide synthesis, then purified and combined in a reaction that locks them together for greater performance and shelf life.
The original backbone of Dipeptide Diaminobutyroyl Benzylamide Diacetate was inspired by research into compounds found in temple viper venom, which showed a gentle ability to relax facial tension. Cosmetic chemists soon realized that when this tripeptide is linked with a larger oligopeptide like Oligopeptide-133 the result is a multi tasking skin conditioner that feels elegant and lightweight. Since the early 2010s the peptide complex has appeared in premium skin care, especially products that promise a smoother, well rested look without the sting of more aggressive actives.
Today you will usually see Dipeptide Diaminobutyroyl Benzylamide Diacetate Oligopeptide-133 in leave on formulas such as anti aging serums, eye creams, sheet masks, ampoules, lightweight moisturizers and targeted wrinkle treatments. Because it works at low concentrations and plays well with common hydrators and antioxidants it has become a favorite for minimalist yet high performance blends.
Dipeptide Diaminobutyroyl Benzylamide Diacetate Oligopeptide-133’s Cosmetic Benefits/Uses
The main role this peptide complex serves in skin care is skin conditioning. By binding lightly to the surface of the skin it helps attract and hold water, leaving the complexion softer, smoother and more supple. Regular use can improve the feel of rough or tired looking areas, support a healthier moisture barrier and give fine lines a temporarily relaxed appearance, all without heavy oils or waxes.
Who Can Use Dipeptide Diaminobutyroyl Benzylamide Diacetate Oligopeptide-133
This peptide complex is generally suitable for all skin types including dry, normal, combination, oily and even sensitive skin because it conditions without clogging pores or leaving a greasy film. Those with very reactive or allergy-prone skin should still check the full ingredient list of a finished product to be sure no other components pose a concern but the peptide itself is considered gentle.
The ingredient is synthesized entirely in the lab using plant-derived amino acid building blocks so it is appropriate for both vegetarians and vegans.
Current safety data does not flag the peptide as an issue for pregnant or breastfeeding women when used topically at the tiny levels found in cosmetics. This is not medical advice and anyone who is pregnant or nursing should have their healthcare provider review any skincare they plan to use just to be safe.
Dipeptide Diaminobutyroyl Benzylamide Diacetate Oligopeptide-133 does not increase photosensitivity. Normal daytime sun protection habits are still recommended because UV damage is a leading cause of skin aging but the peptide itself will not make skin more reactive to the sun.
Potential Side Effects/Adverse Reactions
Side effects from topical Dipeptide Diaminobutyroyl Benzylamide Diacetate Oligopeptide-133 can vary from person to person. The points below list potential reactions but they are uncommon when the ingredient is used at cosmetic levels and correctly formulated.
- Mild redness or warmth Usually short-lived and resolves once the product is removed
- Itching or tingling May occur on very sensitive skin if the overall formula contains other stimulatory ingredients
- Contact dermatitis Rare allergic response typically linked to individual sensitivity rather than the peptide itself
- Eye irritation Possible if a product migrates into the eyes though the peptide is not classified as an ocular irritant on its own
If any persistent or serious reaction occurs discontinue use immediately and seek medical advice.
Comedogenic Rating
Rating: 0/5. Dipeptide Diaminobutyroyl Benzylamide Diacetate Oligopeptide-133 is a water-soluble peptide with no oily or waxy components so it does not block pores or encourage buildup inside follicles. Its molecules rinse cleanly if washed off and remain lightweight in leave-on products. This makes it suitable for people who are prone to acne or breakouts. Keep in mind that the overall formula still matters because heavier emulsifiers or fragrances in the same product could raise the pore-clogging potential.
Summary
Dipeptide Diaminobutyroyl Benzylamide Diacetate Oligopeptide-133 is mainly a skin-conditioning peptide that hydrates the surface, softens texture and helps facial skin look calmer and less lined. It does this by binding moisture and gently relaxing tension at the top layers of the skin which leaves a smoother, more supple finish without heaviness.
The complex is popular in modern anti-aging serums and eye treatments yet remains a niche ingredient compared with classic hydrators like hyaluronic acid. Brands that favor a science-driven minimalist approach use it for its multitasking effect at low concentrations.
Current data shows it is low risk for irritation or sensitivity when used as directed. Still, everyone’s skin is unique so it is wise to patch test any new product that contains this peptide before applying it to the full face.