Disodium 2-Sulfopalmitate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Disodium 2-Sulfopalmitate?

Disodium 2-sulfopalmitate is a salt derived from palmitic acid, a fatty acid that occurs naturally in palm oil, some animal fats and certain plant oils. Chemically, it combines palmitic acid with a sulfonate group, then neutralizes it with sodium, creating a water-soluble cleansing agent. The ingredient was first explored by soap makers looking for milder, sulfate-free cleansers that still produce a satisfying lather. Over time formulators in the personal care industry adopted it as an alternative to harsher surfactants like sodium lauryl sulfate.

Production begins with palmitic acid, which is reacted with sulfur trioxide to introduce the sulfonate group. The resulting acid is then neutralized with sodium hydroxide, giving the disodium salt. This process yields a fine powder or granule that dissolves easily in water.

You will most often find disodium 2-sulfopalmitate in facial cleansers, body washes, shampoo bars, micellar waters and baby wash formulas. It can also appear in foaming masks and some gentle exfoliating scrubs where a mild yet effective cleanser is needed.

Disodium 2-Sulfopalmitate’s Cosmetic Benefits/Uses

In skin and hair care formulas disodium 2-sulfopalmitate is prized for the following role:

  • Cleansing: Acts as a surfactant that lifts oil, dirt and makeup from the skin or hair so they can be rinsed away. It creates a soft foam, helps water mix with oils and leaves the surface feeling fresh without the tight, stripped sensation linked to stronger detergents.

Who Can Use Disodium 2-Sulfopalmitate

Thanks to its gentle surfactant profile, disodium 2-sulfopalmitate generally suits all skin types, including dry, sensitive, combination and oily. Its mild cleansing action helps remove grime without stripping natural oils, so most people tolerate it well. Those with very reactive or eczema-prone skin may still prefer to proceed cautiously since any surfactant can be over-drying if left on too long or used too frequently.

The ingredient can be vegan friendly when the palmitic acid is sourced from plants such as sustainable palm or coconut oil. Brands that cater to vegans usually highlight this on the label. If the source is animal fat, vegetarians and vegans would want to avoid it, so checking with the manufacturer is wise.

No specific warnings exist for pregnant or breastfeeding women regarding disodium 2-sulfopalmitate in rinse-off products. It is considered low risk, though this is not medical advice. Anyone who is expecting or nursing should still run new skincare products past a qualified healthcare provider to be safe.

The ingredient does not increase photosensitivity, so it will not make skin more prone to sunburn. It is also compatible with most common skincare actives, and no special storage or handling precautions are needed beyond keeping the product sealed and away from excessive heat.

Potential Side Effects/Adverse Reactions

Reactions to topical disodium 2-sulfopalmitate vary from person to person. The effects below are possible yet uncommon when the ingredient is used correctly in a well-formulated product.

  • Mild skin dryness or tightness
  • Temporary stinging or redness in very sensitive skin
  • Allergic contact dermatitis in individuals with a specific sulfonate sensitivity
  • Eye irritation if foam or solution accidentally gets into the eyes

If any irritation or adverse reaction occurs stop using the product and consult a healthcare professional or dermatologist for guidance

Comedogenic Rating

Rating: 0 / 5

Disodium 2-sulfopalmitate is highly water soluble and designed to rinse off completely, so it does not linger in pores or leave an oily film that could trap dead cells. As a result it carries virtually no risk of clogging pores, making it suitable for people who are prone to acne or breakouts. Because it is a surfactant used in wash-off formulas, any brief contact with skin is unlikely to influence sebum oxidation or comedone formation.

Summary

Disodium 2-sulfopalmitate functions mainly as a mild cleansing agent that lifts oil, dirt and makeup then rinses away without stripping natural moisture. It achieves this by surrounding oily particles with its surfactant head, allowing water to wash them off easily.

The ingredient is not a household name but formulators looking for gentle sulfate-free options appreciate its balanced foaming action, so it shows up more often in modern face washes, body cleansers and shampoo bars.

Overall safety data are strong and adverse reactions are rare, especially in rinse-off products. Still, skin can react unpredictably, so it is wise to patch test any new product containing disodium 2-sulfopalmitate before full use.

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