Disodium Isostearamido Mea-Sulfosuccinate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Disodium Isostearamido Mea-Sulfosuccinate?

Disodium Isostearamido Mea-Sulfosuccinate is a mild surfactant made by combining isostearic acid, a fatty acid often sourced from vegetable oils, with a sulfosuccinic acid derivative then neutralizing the mix with sodium. The result is a water-soluble powder or paste that carries both oil-loving and water-loving parts, letting it mix dirt with water so it can be rinsed away. First explored in the late 1970s as chemists searched for gentler foaming agents, it quickly found favor in shampoos and body washes that needed to clean without stripping skin. Today manufacturers produce it in large reactors where fatty acids are reacted with amino alcohols, treated with sulfosuccinic anhydride, then neutralized and purified. You will spot it in sulfate-free shampoos, facial cleansers, bubble baths, baby washes, micellar waters, cream cleansers and even some moisturizing body lotions that need a light foaming touch.

Disodium Isostearamido Mea-Sulfosuccinate’s Cosmetic Benefits/Uses

This multi-tasking ingredient brings several perks to modern formulas

  • Cleansing – lifts away oil, sweat and residue so skin and hair feel fresh
  • Foaming – creates a rich lather that spreads product easily and gives a pleasant sensory feel
  • Skin Conditioning – leaves a light, soft film that helps skin feel smooth after rinsing
  • Foam Boosting – teams up with other surfactants to increase the volume and stability of bubbles
  • Hydrotrope – keeps otherwise tricky ingredients dissolved in water-based formulas, preventing separation

Who Can Use Disodium Isostearamido Mea-Sulfosuccinate

This gentle surfactant suits most skin types including dry, normal, combination, oily and even sensitive because it cleans without aggressively stripping natural oils. Those with very reactive or allergy-prone skin should still check the full ingredient list since any surfactant has a small risk of irritation if overused or left on too long.

The compound is typically sourced from plant-based fatty acids and undergoes synthetic processing with no animal-derived inputs so it is generally acceptable for vegans and vegetarians. Always verify with the individual brand if strict cruelty-free or vegan certification matters to you.

No studies have pointed to concerns for women who are pregnant or breastfeeding when the ingredient is used in rinse-off products at standard concentrations. That said this is not medical advice and anyone expecting or nursing should show the product to a qualified healthcare provider before adding it to a routine just to be safe.

Disodium Isostearamido Mea-Sulfosuccinate does not increase sun sensitivity and it can be paired with daytime products that contain SPF without special precautions.

Potential Side Effects/Adverse Reactions

Responses to topical Disodium Isostearamido Mea-Sulfosuccinate vary from person to person. The points below cover potential issues but most people will not notice any problems when the ingredient is formulated and used correctly.

  • Mild skin irritation such as redness or itching
  • Transient stinging if the cleanser contacts the eyes
  • Dryness or tightness if used in very high concentrations or with prolonged contact
  • Rare allergic contact dermatitis in individuals sensitized to sulfosuccinates

If you experience discomfort or any persistent reaction stop using the product and seek guidance from a medical professional or dermatologist.

Comedogenic Rating

Rating: 1 (very low risk)

Although the molecule is built from a fatty acid, it is chemically modified to be highly water soluble and is used in rinse-off formulas, so it does not linger on skin to block pores. Lab data and product experience show almost no reports of acne flare-ups linked to this surfactant.

Suitable for people prone to acne or breakouts.

Because it is nearly always used alongside other cleansing agents, the final formula matters more than the individual ingredient. Heavy creams or leave-on products that include it could still trigger clogging if they contain other pore-blocking ingredients.

Summary

Disodium Isostearamido Mea-Sulfosuccinate acts as a gentle cleanser, foam creator, skin conditioner, foam booster and hydrotrope. Its dual oil-loving and water-loving structure lifts dirt then rinses clean while leaving a soft feel. By stabilising bubbles and keeping tricky actives dissolved, it helps formulators build pleasant sulfate-free washes.

It enjoys steady use in modern shampoos, face washes and baby cleansers, though it is not a household name because labels often list several surfactants together. Chemists appreciate its mildness and versatility so it pops up frequently in new gentle cleansing launches.

Current research and decades of consumer use show it is safe in typical rinse-off concentrations, with only rare irritation reports. As with any new skincare product, patch testing is a smart precaution to spot personal sensitivities before full use.

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