Disodium Isostearamido Mipa-Sulfosuccinate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Disodium Isostearamido Mipa-Sulfosuccinate?

Disodium Isostearamido Mipa-Sulfosuccinate is a synthetic surfactant made by reacting isostearic acid, derived from vegetable or animal fats, with a mild amino alcohol called MIPA (mono-isopropanolamine) then attaching a sulfosuccinate group and neutralizing the result with sodium. The finished molecule carries two sodium ions that help it dissolve easily in water while its long isostearic chain loves oil, letting it bridge the gap between the two. First developed in the 1970s as formulators searched for gentler lathering agents than traditional sulfates, it quickly found a place in personal care because it cleans well without stripping skin or hair.

Production starts with isostearic acid that is amidated with MIPA to form isostearamido MIPA. This intermediate is then esterified with sulfosuccinic anhydride to introduce the sulfonate group. A final neutralization step with sodium hydroxide converts the acid into its disodium salt, yielding a free-flowing powder or viscous liquid that is easy to dose during manufacturing.

You will most often spot Disodium Isostearamido Mipa-Sulfosuccinate in facial cleansers, micellar waters, sulfate-free shampoos, bubble baths, body washes, gentle baby products, exfoliating scrubs and even some makeup removers. Brands like it because it pairs a creamy foam with a soft after-feel, so it shows up in daily-use formulas that need to balance thorough cleansing with skin comfort.

Disodium Isostearamido Mipa-Sulfosuccinate’s Cosmetic Benefits/Uses

This multi-tasking ingredient improves both how a product performs and how it feels on skin or hair.

  • Cleansing: Its surfactant nature lifts away dirt, excess oil and makeup so products rinse clean without heavy residue
  • Foaming: Creates a rich lather that signals cleanliness to users and helps spread the product evenly
  • Skin conditioning: Leaves behind a light emollient film that reduces the tight, squeaky sensation often caused by harsher detergents
  • Foam boosting: Enhances and stabilizes bubbles when used alongside other surfactants allowing formulators to cut back on sulfates while keeping a satisfying foam
  • Hydrotrope: Improves the solubility of oily or fragrance components in water-based formulas which keeps products clear and prevents separation

Who Can Use Disodium Isostearamido Mipa-Sulfosuccinate

This surfactant is considered gentle enough for most skin types including dry, oily, combination, sensitive or mature skin because it cleans without stripping the natural barrier. Very reactive or eczema-prone skin may still prefer a shorter ingredient list so patch monitoring is wise.

The raw material can be sourced from either plant or animal fats. Brands that follow a vegan or vegetarian standard will specify a vegetable origin or use third-party certification, so label readers should look for that confirmation if avoiding animal-derived inputs is important.

No research indicates that the ingredient penetrates deeply or enters the bloodstream in meaningful amounts, so products containing it are generally viewed as safe for use during pregnancy or while breastfeeding. This is not medical advice and anyone who is pregnant or nursing should run their routine past a qualified healthcare provider to be sure.

Disodium Isostearamido Mipa-Sulfosuccinate does not increase photosensitivity and has no known interactions with sun exposure. It is also color-safe for treated hair and compatible with most other skincare actives.

Potential Side Effects/Adverse Reactions

Responses to any cosmetic ingredient can vary from person to person. The following are potential, not expected, effects and most users will not experience them when the product is formulated and used as directed.

  • Mild eye stinging if the cleanser accidentally gets into the eyes
  • Transient skin tightness or dryness when used in very high concentrations
  • Temporary redness or irritation on extremely sensitive or compromised skin
  • Rare allergic contact dermatitis presenting as itching, rash or swelling

If irritation or any adverse reaction occurs stop use immediately and consult a healthcare professional if symptoms persist.

Comedogenic Rating

Rating: 1/5. Disodium Isostearamido Mipa-Sulfosuccinate is highly water-soluble and designed for rinse-off products so it does not linger on skin long enough to block pores. Its large, charged structure prefers to stay in the wash water rather than nestle into sebum which further lowers clogging potential. Formulas typically use it at modest levels alongside other mild surfactants, diluting any residue that might remain.

Because it scores a 1 this ingredient is generally considered suitable for acne-prone or breakout-prone skin.

Worth noting: if a cleanser is heavily packed with oils or butters the overall formula could still feel heavy even when this surfactant itself is low on the scale.

Summary

Disodium Isostearamido Mipa-Sulfosuccinate works as a gentle cleanser, foam creator, foam booster, light skin conditioner and hydrotrope. Its dual nature—an oil-loving tail plus water-loving sulfonate head—lets it surround dirt and oils so they rinse away while stabilizing a creamy lather. The mild amide backbone softens the feel of the surfactant blend leaving skin comfortable instead of tight.

While not a household name it is quietly popular among formulators crafting sulfate-free face washes, baby baths and color-safe shampoos that still need satisfying bubbles. You will see it more often in mid- to premium ranges that focus on a gentle cleansing story.

Safety reviews place it in the low-risk category with irritation rare at normal use levels. As with any new skincare product a quick patch test is a smart extra step to be sure your individual skin is happy.

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