Disodium Malyl Tyrosinate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Disodium Malyl Tyrosinate?

Disodium Malyl Tyrosinate is the salt form of an amino acid derivative made by combining L-tyrosine with malic acid then neutralizing the blend with sodium. The result is a water-soluble powder that dissolves easily in cosmetic formulas. Because tyrosine is naturally found in many proteins and malic acid is present in fruits like apples, the raw materials are familiar to the body which helps make the ingredient gentle on skin.

Interest in this compound began in the late 1990s when formulators looked for amino acid-based agents that could soften skin without leaving a heavy feel. By attaching malic acid to tyrosine they created a molecule that bonds well with water and skin proteins, giving a light yet conditioning effect. Today, production typically involves fermenting plant-sourced glucose to obtain L-tyrosine, reacting it with purified malic acid, then adding food-grade sodium hydroxide to form the stable disodium salt. The final material is filtered, dried and milled to a fine powder ready for cosmetic use.

You will most often see Disodium Malyl Tyrosinate in hydrating sheet masks, lightweight moisturizers, soothing cleansers, micellar waters and post-sun care gels. Its mild profile makes it popular in formulations aimed at sensitive or combination skin where a balance of cleansing and conditioning is required.

Disodium Malyl Tyrosinate’s Cosmetic Benefits/Uses

This ingredient delivers two main functions in skincare products

  • Skin conditioning: It helps bind water to the outer skin layer so the surface feels softer smoother and more supple without a greasy afterfeel. The amino acid portion can also support the skin’s natural protein structure which may improve overall tone and comfort.
  • Cleansing: Its mild acidity and water-loving nature assist in lifting away excess oil dirt and makeup. Because it is less harsh than many classic surfactants it can cleanse while still leaving the skin barrier intact making it suitable for daily or sensitive-skin routines.

Who Can Use Disodium Malyl Tyrosinate

Thanks to its mild nature and water-binding ability this ingredient suits nearly every skin type including dry, normal, combination and sensitive skin. Oily and acne-prone users often like it because it conditions without adding extra oil while those with easily irritated skin appreciate the low chance of stinging or barrier disruption. The only groups that may wish to proceed with caution are people who know they react badly to sodium salts or fruit-derived acids since the malic acid portion could theoretically trigger sensitivity in those rare cases.

Disodium Malyl Tyrosinate is produced from plant-fermented glucose and mineral sodium so it is free from animal derivatives making it appropriate for vegans and vegetarians.

No data suggest the ingredient poses a risk during pregnancy or breastfeeding when used topically in standard cosmetic concentrations. This is not medical advice and anyone who is pregnant or nursing should confirm suitability with a healthcare professional before adding new products to a routine.

The molecule is not known to increase photosensitivity so daytime use does not require extra sun protection beyond the normal daily SPF every dermatologist recommends. It is also odorless colorless and compatible with most other common skincare ingredients which makes it easy to slot into existing routines.

Potential Side Effects/Adverse Reactions

Responses to topical Disodium Malyl Tyrosinate vary from person to person. The effects listed below are possible but uncommon when the ingredient has been formulated and preserved correctly.

  • Mild transient redness or warmth immediately after application
  • Light tingling or stinging on very compromised or freshly exfoliated skin
  • Localized dryness if used in a high concentration without accompanying moisturizers
  • Rare allergic contact dermatitis marked by persistent itching swelling or rash
  • Eye irritation if the product accidentally enters the eyes

If any of these effects occur discontinue use and consult a qualified medical professional for guidance.

Comedogenic Rating

Rating: 0 / 5

Disodium Malyl Tyrosinate is a small water-soluble salt with no oily or waxy components that could clog pores. It rinses away easily and leaves minimal residue so it earns the lowest possible score. This makes it generally suitable for people prone to acne or breakouts.

No data suggest the molecule interacts with sebum oxidation or bacterial growth, two factors that often contribute to comedogenesis. Because it is used at low percentages and usually paired with non-occlusive bases, its pore-friendly profile holds across most product formats.

Summary

Disodium Malyl Tyrosinate serves mainly as a skin conditioner and gentle cleanser. The tyrosine segment attracts and holds water on the skin surface for a soft smooth feel while the malic portion helps lift impurities without stripping the barrier. Together they give lightweight hydration, mild cleansing action and enhanced comfort.

Although not as famous as hyaluronic acid or glycerin this ingredient is steadily gaining attention in modern gel creams, micellar waters and sensitive-skin cleansers thanks to its gentle multitasking nature.

Available safety data show it is low risk, non-sensitizing and non-comedogenic when used as directed. As with any new skincare addition it is smart to perform a brief patch test to confirm personal compatibility.

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