Disodium Soyamphodiacetate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Disodium Soyamphodiacetate?

Disodium Soyamphodiacetate is a soy-derived amphoteric surfactant, meaning it can carry either a positive or negative charge depending on the surrounding pH. It is produced by reacting fatty acids obtained from soybean oil with chloroacetic acid, followed by neutralisation with sodium hydroxide. The result is a mild, water-soluble compound that fits well into gentle skincare and haircare formulas.

The ingredient started gaining attention in the late 1990s when formulators were looking for plant-based alternatives to harsher sulfates. Soybeans, already abundant in the food industry, offered an eco-friendly raw material that could be processed into effective yet mild cleansing agents. Over time, Disodium Soyamphodiacetate became a staple in products marketed as sulfate-free or suitable for sensitive skin.

You will most often find it in facial cleansers, shower gels, baby shampoos, micellar waters, lightweight moisturisers, sheet masks and even some leave-in hair treatments. Because it balances cleansing power with skin friendliness it is favoured in formulations that promise gentle daily use.

Disodium Soyamphodiacetate’s Cosmetic Benefits/Uses

Here is how this multitasking ingredient supports cosmetic formulas:

  • Cleansing: Lifts away dirt, oil and product residue without stripping the skin or hair of natural moisture, making it ideal for sensitive or dry skin types
  • Viscosity Controlling: Helps adjust and stabilise the thickness of gels, lotions and shampoos so the product feels pleasant and consistent from the first use to the last

Who Can Use Disodium Soyamphodiacetate

This gentle surfactant suits almost every skin type including dry, oily, combination and sensitive skin because it cleans without stripping natural moisture. People with a known soy allergy should be cautious since the ingredient is derived from soybeans and trace proteins may remain, though this is uncommon.

Disodium Soyamphodiacetate is plant derived and contains no animal by-products so it is generally considered appropriate for vegetarians and vegans. Always confirm the full formula is free of animal derivatives if that is a priority.

There are no reports indicating that the ingredient poses a specific risk to pregnant or breastfeeding women when used topically in rinse-off or leave-on products. This is not medical advice and anyone who is pregnant or nursing should have all skincare products reviewed by a qualified healthcare professional to be certain they are suitable.

The ingredient does not increase photosensitivity and does not interact with UV light, so it will not make skin more prone to sunburn. Aside from possible issues for individuals with a soy allergy there are no other notable restrictions on who may use products containing Disodium Soyamphodiacetate.

Potential Side Effects/Adverse Reactions

Reactions to topical Disodium Soyamphodiacetate are uncommon but can vary from person to person. The points below outline potential side effects yet most users will not experience them when the ingredient is properly formulated and used as directed.

  • Mild skin irritation such as redness or itching, usually linked to very sensitive skin or use of a highly concentrated product
  • Allergic contact dermatitis for individuals who have an existing soy allergy or develop sensitivity over time
  • Eye stinging or watering if the ingredient enters the eyes in an inadequately diluted form
  • Temporary scalp or hair dryness when combined with other stronger surfactants in a formula that lacks sufficient moisturising agents

If any of these effects occur stop using the product and consult a healthcare professional for guidance.

Comedogenic Rating

Rating: 0. Disodium Soyamphodiacetate is a water-soluble surfactant that rinses away cleanly and does not leave oily residues that could block pores. It also has a relatively low molecular weight which helps it stay on the skin surface only briefly before being washed off. For these reasons it is considered non-comedogenic and is generally suitable for people who are prone to acne or breakouts. Because it is usually paired with other mild cleansing agents, it rarely builds up on the skin even with daily use.

Summary

Disodium Soyamphodiacetate is a soy-based ingredient that cleanses skin and hair while helping to control product thickness. It works by surrounding dirt and oil so they can be rinsed away easily and by interacting with other ingredients to keep gels and shampoos at a pleasant consistency. Although not as famous as coconut-derived surfactants, it is steadily found in gentle cleansers, baby shampoos and sulfate-free formulas thanks to its mild nature and plant origin. Overall it is regarded as safe for topical use with very few reports of irritation aside from rare soy-related allergies. As with any new product a quick patch test is wise to confirm personal compatibility.

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