Duboisia Leichhardtii Leaf Extract: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Duboisia Leichhardtii Leaf Extract?

Duboisia Leichhardtii Leaf Extract comes from the leaves of Duboisia leichhardtii, a small evergreen tree that grows in Australia and belongs to the nightshade family. The leaves are naturally rich in alkaloids such as scopolamine and hyoscyamine, compounds known for their calming and soothing properties when used on skin. Indigenous communities valued the plant long before modern skincare adopted it, and interest grew as researchers looked for botanical ways to reduce irritation and improve skin feel. To make the extract, growers harvest mature leaves, dry and grind them, then soak the plant matter in a water or water-glycol mix to pull out the beneficial molecules. The liquid is filtered, concentrated, and standardized so each batch delivers consistent performance in formulas. You will usually spot this extract in moisturizers, soothing creams, masks, after-sun gels, anti-aging serums, and other leave-on treatments where a gentle skin-comforting effect is desired.

Duboisia Leichhardtii Leaf Extract’s Cosmetic Benefits/Uses

This botanical is mainly added to products for its skin conditioning ability, helping the outer layer feel softer, smoother, and more balanced. By supporting a calm barrier it can ease the look of redness and dryness, making a formula feel more comforting and luxurious on application.

Who Can Use Duboisia Leichhardtii Leaf Extract

This extract suits most skin types, including normal, dry, combination and oily, because its main job is to condition and calm without leaving a heavy or greasy residue. Sensitive skin can usually tolerate it since the plant compounds are chosen for their soothing nature, though anyone with known nightshade allergies should steer clear because cross-reactivity is possible. The ingredient is plant derived and typically processed with water or water-glycol solutions, so it is considered suitable for vegans and vegetarians. Duboisia Leichhardtii Leaf Extract is not known to pose special risks during pregnancy or while breastfeeding when used topically and in cosmetic concentrations, but this is not medical advice; anyone expecting or nursing should confirm product choices with a qualified healthcare provider. The extract does not make skin more prone to sunburn, so it is not classed as photosensitising. If a formula also contains other actives that increase sun sensitivity, follow the usual daytime sunscreen routine.

Potential Side Effects/Adverse Reactions

Reactions to topical Duboisia Leichhardtii Leaf Extract vary between individuals. The following list covers potential side effects, but most people will not experience them when using a well-formulated product.

  • Skin irritation or redness – may occur in very sensitive users, especially if the product also contains strong fragrances or exfoliating agents
  • Allergic contact dermatitis – rare but possible, particularly in those allergic to other members of the nightshade family
  • Dryness or tightness – can happen if the rest of the formula lacks adequate moisturisers for your skin’s needs
  • Eye irritation – stinging or watering if the product accidentally gets into the eyes
  • Interaction with anticholinergic medication – theoretically possible if large areas of broken skin are treated, because the leaves naturally contain alkaloids with anticholinergic activity

If any uncomfortable reaction develops stop using the product and seek advice from a pharmacist or healthcare professional.

Comedogenic Rating

Rating: 0 / 5. Duboisia Leichhardtii Leaf Extract is water based and contains negligible amounts of pore clogging oils or waxes so it does not create the kind of film that traps sebum and debris. It is therefore unlikely to trigger blackheads or whiteheads. This makes the extract a safe choice for acne-prone or breakout-prone skin. No specific issues have been reported regarding pore blockage even at the higher levels typically used in soothing creams or serums.

Summary

Duboisia Leichhardtii Leaf Extract is chiefly valued for skin conditioning. Its naturally occurring alkaloids help calm visible redness, soften rough patches and support a comfortable skin barrier. Although effective, it remains a niche botanical so you will not find it in as many formulas as bigger name plant extracts like aloe or chamomile. Current safety data shows it is well tolerated for topical use with very low risk of irritation or breakouts. As with any new skincare product a quick patch test behind the ear or on the inner forearm is a smart step before full-face use, just to be sure your skin agrees with it.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search