Ergocalciferol: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Ergocalciferol?

Ergocalciferol is the scientific name for vitamin D2, a fat soluble nutrient that the body normally gets from plant sources and fungi. In nature it comes from ergosterol, a compound found in yeast and mushrooms. When ergosterol is exposed to ultraviolet light it changes into ergocalciferol, a process that cosmetic makers copy in the lab. Large batches of food grade yeast are grown, the ergosterol is extracted then briefly treated with UV lamps. The result is purified vitamin D2 powder that blends easily into creams and oils.

The link between vitamin D and healthy looking skin was noted soon after the vitamin’s discovery in the 1920s. By the late 20th century formulators had begun adding ergocalciferol to moisturizers to give skin conditioning benefits. Today you will spot it in face and body lotions, hand creams, anti aging serums, after sun products, nourishing masks and lip balms.

Ergocalciferol’s Cosmetic Benefits/Uses

In skin care formulas ergocalciferol serves one clear purpose.

As a skin conditioning agent it helps keep skin soft, smooth and comfortable. It supports the natural barrier so moisture stays in and external irritants stay out, which can improve the overall feel of a product and leave skin looking well cared for.

Who Can Use Ergocalciferol

Ergocalciferol suits most skin types including dry, normal, combination and sensitive skin because it reinforces the moisture barrier without feeling greasy. Oily or acne prone skin can usually tolerate it too since the raw ingredient scores low on the comedogenic scale, though breakouts may still occur if the finished formula contains heavy oils or waxes.

Commercial vitamin D2 comes from UV treated yeast or mushrooms so it is plant derived and appropriate for both vegans and vegetarians.

No data links topical ergocalciferol to hormonal disruption and it is widely consumed in prenatal supplements, suggesting a favorable safety profile for pregnant and breastfeeding women. This is not medical advice and anyone who is pregnant or nursing should review the ingredient list with a qualified doctor before use.

The ingredient itself does not make skin more sensitive to sunlight and can be applied during the day. Routine sunscreen use is still recommended for overall protection.

Potential Side Effects/Adverse Reactions

Reactions to topical ergocalciferol vary from person to person. The effects listed below are possible but unlikely for most users when the ingredient is properly formulated and used as directed.

  • Transient tingling or mild warmth especially on freshly exfoliated or broken skin
  • Redness or irritation in very sensitive individuals
  • Allergic contact dermatitis marked by itching swelling or small bumps
  • Acne flare up if the overall formula contains pore clogging oils alongside ergocalciferol

If any adverse reaction occurs discontinue use and consult a healthcare professional.

Comedogenic Rating

Rating: 1/5

Ergocalciferol is an oily, fat soluble molecule yet its particle size is small and it is usually added at very low percentages, so it rarely blocks pores on its own. Laboratory testing places vitamin D2 near the bottom of the comedogenic scale, giving it a rating of 1.

Because of this low score it is generally suitable for people prone to acne or breakouts, provided the rest of the formula is also non-clogging.

The only time pore-clogging issues arise is when ergocalciferol is paired with heavy butters or waxes that raise the overall comedogenic load of a product.

Summary

Ergocalciferol, better known as vitamin D2, is used in cosmetics mainly for its skin conditioning ability. It reinforces the skin’s natural barrier so moisture stays in and irritants stay out, leaving the surface soft smooth and comfortable. The ingredient is plant derived, stable in most cream bases and performs well at low doses which has kept it in steady use across moisturizers, serums and lip balms though it has never been a headline trend.

Topical vitamin D2 is considered very safe with minimal risk of irritation or pore blockage. As with any new skincare ingredient a quick patch test is wise when trying a fresh product just to be cautious.

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