Ethanolamine Hcl: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Ethanolamine Hcl?

Ethanolamine Hcl, formally known as 2-Hydroxyethylammonium chloride, is a salt formed when ethanolamine reacts with hydrochloric acid. The result is a white to off-white crystalline powder that dissolves easily in water. Ethanolamine itself comes from the reaction of ethylene oxide with ammonia, a process developed in the early 20th century for industrial applications. Converting it to the hydrochloride form makes the molecule more stable and easier to handle in cosmetic labs.

The beauty industry began using Ethanolamine Hcl in the mid-1900s as formulators searched for ingredients that could keep products at a skin-friendly pH. Today it is produced in large-scale reactors under controlled temperatures and pressures, then purified and dried to meet cosmetic-grade standards.

You will most often find Ethanolamine Hcl in facial masks, moisturizers, serums, anti-aging creams, hair conditioners and rinse-off cleansers where maintaining the right acidity is key to product performance and skin comfort.

Ethanolamine Hcl’s Cosmetic Benefits/Uses

Ethanolamine Hcl serves a single but important role in cosmetics.

As a buffering agent it helps keep the pH of a formula steady, preventing it from becoming too acidic or too alkaline over time. A stable pH protects the integrity of active ingredients, supports the skin’s natural barrier and improves overall product shelf life.

Who Can Use Ethanolamine Hcl

Ethanolamine Hcl is generally suitable for normal, oily, combination and dry skin because it is used at low concentrations only to balance pH, not to treat skin concerns directly. Those with very sensitive or compromised skin should watch for irritation if the overall formula contains a high level of alkaline ingredients that rely on Ethanolamine Hcl for neutralization.

The ingredient is synthetically produced from petrochemical feedstocks, not animal sources, so it is considered vegan and vegetarian friendly.

Current safety data do not flag Ethanolamine Hcl as unsafe for pregnant or breastfeeding women when used in cosmetics. That said this is not medical advice and anyone who is pregnant or nursing should show the full product label to a healthcare professional before use to be safe.

Ethanolamine Hcl does not increase photosensitivity, so it will not make skin more vulnerable to sunburn. It is also odorless and does not interfere with fragrance profiles or colorants in a formula.

Potential Side Effects/Adverse Reactions

Individual responses to topical Ethanolamine Hcl can differ. The points below outline possible side effects, but they are uncommon when the ingredient is used at the low levels typical of finished cosmetics.

  • Skin irritation – transient redness stinging or burning if the surrounding formula is not balanced correctly
  • Contact dermatitis – rare allergic reaction manifesting as rash or swelling
  • Dryness or tightness – may occur if a product has an overall high pH even after buffering
  • Eye irritation – tearing or discomfort if a product accidentally enters the eyes during use
  • Increased penetration of other actives – very slight pH shifts might enhance the uptake of potent acids which can amplify their effects

If any discomfort or unusual reaction occurs stop using the product and consult a qualified healthcare professional or dermatologist.

Comedogenic Rating

Rating: 0 / 5

Ethanolamine Hcl is a small water-soluble salt that does not leave an oily or occlusive film on skin so it has virtually no ability to clog pores. Because its job is purely to fine-tune pH rather than add emolliency or texture it rinses away easily in cleansers and is present at very low levels in leave-on products.

Suitable for acne-prone or breakout-prone skin.

Only the overall formulation, not Ethanolamine Hcl itself, will influence how pore-clogging a finished product may be.

Summary

Ethanolamine Hcl acts as a buffering agent that stabilises pH, keeps actives effective and supports skin comfort by preventing formulas from drifting too acidic or too alkaline. It does this by supplying both a weak base and its corresponding salt, letting it neutralise small pH changes throughout a product’s shelf life.

The ingredient is more of a behind-the-scenes helper than a star so it is not widely advertised yet it appears in many masks, creams and cleansers that need reliable pH control.

Current data show it is safe at the low concentrations used in cosmetics, with irritation being uncommon. As with any new skincare product sensible patch testing is recommended to make sure your skin agrees with the full formula.

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