Ethyl Nicotinate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Ethyl Nicotinate?

Ethyl Nicotinate is the ester form of nicotinic acid, more commonly called niacin, combined with ethanol. In simple terms it is a small molecule made when the vitamin niacin is reacted with alcohol to create a liquid that blends easily with oils and water based ingredients. Because it carries the familiar scent of niacin yet dissolves smoothly, formulators began exploring it for beauty products in the mid-20th century as perfumery shifted toward lighter, fresher notes. Today most commercial supplies are produced through a controlled reaction between niacin and ethanol, followed by purification and quality testing to meet cosmetic grade standards.

You are most likely to find Ethyl Nicotinate in leave-on skin treatments, lightweight moisturizers, targeted anti-aging serums, sheet masks and aromatic body lotions. Its versatility means it can sit in both water and oil phases, letting chemists slip it into a variety of textures from gels to creams.

Ethyl Nicotinate’s Cosmetic Benefits/Uses

In formulas Ethyl Nicotinate serves two main roles that bring noticeable value to both the product and the user.

  • Perfuming: Adds a gentle, slightly sweet aroma that can round out fragrance profiles without overpowering the senses. This helps mask any raw ingredient smells and gives the finished product a more inviting scent.
  • Skin Conditioning: Supports a softer, smoother feel by helping the skin surface stay supple. It can improve product spreadability so creams glide on easily while leaving a light, non-greasy finish.

Who Can Use Ethyl Nicotinate

Most skin types tolerate Ethyl Nicotinate well, including normal, dry, combination and oily complexions. Individuals with very sensitive or reactive skin, especially those prone to flushing or rosacea, might notice temporary warmth or redness because nicotinate esters can boost surface circulation.

The ingredient is manufactured synthetically from niacin and ethanol, both of which are sourced without animal by-products, so it is generally considered suitable for vegans and vegetarians.

There is no specific research suggesting that topical Ethyl Nicotinate poses a risk to pregnant or breastfeeding women when used in standard cosmetic concentrations. This is not medical advice and anyone who is pregnant or nursing should ask a healthcare provider before using new skincare items to be safe.

Ethyl Nicotinate is not known to cause photosensitivity and does not require special sun precautions beyond daily sunscreen use already recommended for skin health.

Potential Side Effects/Adverse Reactions

Reactions to topical Ethyl Nicotinate can vary from person to person. The points below outline potential side effects although most users will not experience them when the ingredient is used correctly in a well-formulated product.

  • Transient flushing or warmth a brief pinkness or heated sensation as blood flow increases at the application site
  • Mild stinging or tingling usually subsides within minutes but may feel uncomfortable on freshly exfoliated or compromised skin
  • Localized irritation dryness itchiness or a rough texture if the formula is too strong for the individual’s tolerance
  • Allergic contact dermatitis rare red itchy patches or small blisters in those with a specific sensitivity to nicotinate compounds
  • Exacerbation of pre-existing rosacea increased redness in users already prone to vascular flare-ups

If any persistent or severe reaction occurs stop using the product and consult a medical professional or dermatologist.

Comedogenic Rating

Rating: 1/5. Ethyl Nicotinate is a lightweight ester that does not leave an occlusive film on the skin and is typically used at low concentrations, so it has little tendency to clog pores. Its quick absorption and fluid texture let it dissipate without trapping dead cells or sebum inside follicles. Because of this low score it is generally fine for people prone to acne or breakouts.

One extra point worth noting is that the transient increase in surface blood flow some users feel is not related to comedogenicity, so any temporary flushing should not be confused with pore blockage.

Summary

Ethyl Nicotinate primarily acts as a mild fragrance booster and a skin conditioning agent, lending a pleasing scent while helping products glide on smoothly and leave skin feeling supple. These benefits stem from its small molecular size and dual affinity for water and oil which allow it to distribute evenly through a formula and across the skin.

The ingredient sits in the niche category of utility esters: useful, yet not a headline star. You will see it occasionally in lotions, serums and sheet masks but it is not as common as big name actives like hyaluronic acid or vitamin C.

Overall safety is high when used at typical cosmetic levels, with most side effects limited to brief warmth in sensitive individuals. As with any new skincare item it is smart to do a quick patch test before full use to make sure your skin agrees with the formula.

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