Ethyltrimonium Chloride Methacrylate/Hydroxyethylacrylamide Copolymer: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Ethyltrimonium Chloride Methacrylate/Hydroxyethylacrylamide Copolymer?

Ethyltrimonium Chloride Methacrylate/Hydroxyethylacrylamide Copolymer is a synthetic polymer created by linking two building blocks: 2-trimethylammonioethyl methacrylate chloride and hydroxyethylacrylamide. The first part carries a quaternary ammonium group that is positively charged, while the second part contains a hydroxyl group that boosts water affinity. Together they form a flexible, water-soluble film on hair strands.

Chemists first explored this type of copolymer in the late 1990s when brands wanted lightweight alternatives to heavy silicones. Through free-radical polymerization the two monomers are blended in water, triggered with an initiator, then neutralized and filtered to create a clear viscous solution. Because the starting materials are man-made and produced in large batches, the polymer offers consistent quality and is easy to scale for commercial use.

You will mainly spot this ingredient in rinse-off and leave-in hair products such as shampoos, conditioners, hair masks, styling creams, mousses, gels and setting sprays. Its ability to coat each strand without weighing it down has also earned it a place in some anti-frizz serums and color-protection formulas.

Ethyltrimonium Chloride Methacrylate/Hydroxyethylacrylamide Copolymer’s Cosmetic Benefits/Uses

In cosmetic formulations this copolymer delivers two standout benefits:

  • Film forming – it creates a thin, invisible layer that helps lock in moisture, smooth the cuticle and protect hair from humidity which can reduce frizz and improve shine
  • Hair conditioning – the positive charge of the quaternary ammonium group is attracted to the negatively charged surface of damaged hair, helping to detangle, soften and make strands feel silkier after rinsing
Who Can Use Ethyltrimonium Chloride Methacrylate/Hydroxyethylacrylamide Copolymer

This copolymer is generally well tolerated by all scalp and hair types, including oily, dry, color treated and chemically relaxed hair. Because it is water soluble and lightweight it seldom builds up so even fine or low-porosity hair usually benefits without feeling weighed down.

The ingredient is synthetic and contains no animal-derived components, making it suitable for vegans and vegetarians.

No research shows that the polymer poses special risks for women who are pregnant or breastfeeding when applied topically in rinse-off or leave-in hair products. That said, this is not medical advice and anyone who is pregnant or nursing should check with a healthcare professional before adding new products to a routine.

Ethyltrimonium Chloride Methacrylate/Hydroxyethylacrylamide Copolymer does not cause photosensitivity so it will not increase sun sensitivity or interfere with sunscreen performance.

Potential Side Effects/Adverse Reactions

Side effects from topical use of Ethyltrimonium Chloride Methacrylate/Hydroxyethylacrylamide Copolymer vary from person to person. The issues listed below are only potential reactions and, when the ingredient is used correctly in a well-formulated product, most people will not experience them.

  • Scalp irritation – very sensitive scalps might notice mild itching or redness, often due to high product concentration or existing skin conditions like eczema
  • Eye irritation – if the product accidentally gets into the eyes the polymer film can cause temporary stinging or watering
  • Product buildup – overuse in heavy styling formulas may leave a film that makes hair feel coated or dull though this is uncommon and usually resolves with a clarifying shampoo
  • Allergic contact dermatitis – rare but possible if someone is allergic to quaternary ammonium compounds leading to rash or inflammation

If any uncomfortable reaction occurs stop using the product and seek advice from a medical professional or pharmacist.

Comedogenic Rating

Rating: 0 (non-comedogenic)

Ethyltrimonium Chloride Methacrylate/Hydroxyethylacrylamide Copolymer has a large molecular size, is highly water soluble and is designed to sit on the surface of hair rather than sink into skin. These traits mean it is very unlikely to block pores or trap oil, so it earns the lowest possible comedogenic score. This makes it suitable for people who are prone to acne or breakouts.

The only caveat is that leave-in hair products can transfer onto facial skin while you sleep. If you notice any residue on your pillowcase a quick rinse of the face in the morning should prevent issues.

Summary

Ethyltrimonium Chloride Methacrylate/Hydroxyethylacrylamide Copolymer works as a film former and hair conditioner. Its positively charged groups bond to the negatively charged areas of damaged hair, creating a smooth even coating that locks in moisture, cuts frizz and boosts shine without heaviness. Because the polymer is water soluble it rinses away cleanly while still delivering slip and detangling benefits.

You will find this ingredient in a growing number of shampoos, conditioners and styling products, although it is not as ubiquitous as silicones or classic quats. Formulators like it because it offers similar conditioning perks while keeping formulas lightweight and easy to wash out.

Current safety data shows very low risk of irritation or sensitization when used in cosmetics. Still, individual reactions can vary so it is wise to patch test any new product that contains this copolymer before regular use.

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