Feruloyl Pentapeptide-71: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Feruloyl Pentapeptide-71?

Feruloyl Pentapeptide-71 is a lab-crafted ingredient formed when ferulic acid, a naturally occurring antioxidant found in plants like rice bran and oats, is linked to a short chain of five amino acids known as Pentapeptide-71. By bringing these two parts together chemists create a stable molecule that blends the protective power of ferulic acid with the skin-friendly nature of peptides. Development began as cosmetic scientists searched for gentler alternatives to heavy synthetic antioxidants. Advances in peptide chemistry in the early 2000s made it possible to attach ferulic acid to a specific peptide sequence, giving rise to Feruloyl Pentapeptide-71. Production takes place in controlled reactors where ferulic acid is activated then bonded to the peptide, followed by purification and drying into a fine powder for easy mixing into formulas.

You will most often see this ingredient in leave-on products designed to guard skin against daily stress. It appears in serums, anti-aging creams, lightweight moisturizers, sheet masks and eye treatments where its antioxidant action helps support overall skin health without adding heaviness or fragrance.

Feruloyl Pentapeptide-71’s Cosmetic Benefits/Uses

Feruloyl Pentapeptide-71 is valued in skin care because it acts as an antioxidant. By neutralizing free radicals created by sunlight pollution and normal metabolism it helps slow the look of premature aging. This protective effect can soften the appearance of fine lines, maintain a brighter tone and keep supporting ingredients like vitamins and plant oils from breaking down too quickly inside the bottle, which improves the shelf life and performance of the final product.

Who Can Use Feruloyl Pentapeptide-71

This peptide-antioxidant blend is light non-comedogenic and fragrance-free which makes it generally suitable for dry normal combination oily and even sensitive skin types. Because it has no occlusive oils or strong acids it rarely triggers breakouts or stinging so acne-prone and redness-prone users tend to tolerate it well.

Feruloyl Pentapeptide-71 is synthesized in a lab from ferulic acid that can be sourced from plants and a peptide built from individual amino acids, none of which require animal by-products. When produced this way it is considered appropriate for vegans and vegetarians, though those following strict lifestyles may want to verify the brand’s supply chain.

No research indicates any specific risk for women who are pregnant or breastfeeding when using the ingredient topically at cosmetic levels. That said this is not medical advice and anyone who is expecting or nursing should run all skincare products past a qualified healthcare professional just to stay on the safe side.

The molecule does not absorb UV light so it does not cause photosensitivity. It also pairs well with common actives like niacinamide vitamin C retinoids and sunscreen filters without compromising their performance.

Potential Side Effects/Adverse Reactions

Reactions to topical Feruloyl Pentapeptide-71 vary from person to person. The points below outline potential side effects which are uncommon when the ingredient is properly formulated and used as directed.

  • Mild skin irritation such as transient tingling or warmth during first uses
  • Redness or flushing especially on very sensitive or compromised skin
  • Contact dermatitis in rare cases where the user is allergic to ferulic acid derivatives or specific preservatives in the formula
  • Eye irritation if the product migrates into the eyes

If any of these effects occur discontinue use and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 0 / 5

Feruloyl Pentapeptide-71 is a small water-soluble molecule without heavy oils waxes or silicones so it does not clog pores or sit on the skin surface. As a result it carries virtually no risk of blocking follicles or worsening blackheads.

Suitable for acne-prone or breakout-prone skin.

Because the ingredient is usually added at low percentages and is often paired with light gel or serum bases its overall formulas also tend to stay non-comedogenic.

Summary

Feruloyl Pentapeptide-71 serves mainly as an antioxidant that shields skin from free-radical damage helping to soften early signs of aging and protect other actives within a formula. It does this by combining the radical-scavenging power of ferulic acid with a peptide carrier that boosts water compatibility and stability.

The ingredient is still a niche player compared with classics like vitamin C or niacinamide but it is steadily gaining attention as brands look for gentler multitasking antioxidants.

Current data shows it is well tolerated by most skin types with minimal irritation risk and no pore-clogging tendency. As with any new skincare item it is wise to perform a small patch test before fully incorporating products containing Feruloyl Pentapeptide-71.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search