Fish Collagen/Glycoproteins: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Fish Collagen/Glycoproteins?

Fish Collagen/Glycoproteins is a blend of collagen peptides and naturally occurring glycoproteins collected from fish cartilage. Collagen is the main protein that gives skin its firmness while glycoproteins are molecules made of protein joined to sugars that help skin hold water. Manufacturers first looked to fish cartilage as a more sustainable option than land-animal sources and soon saw that the smaller collagen molecules from fish absorb well into skin.

Today the ingredient is produced by cleaning the cartilage, using gentle enzymes to break the collagen into smaller chains and separating out the glycoprotein fraction. The result is a fine powder that dissolves easily in water-based formulas.

You will typically see Fish Collagen/Glycoproteins in serums, sheet masks, anti-aging creams, eye treatments, lightweight moisturizers and after-sun gels where extra hydration and a plumping feel are desired.

Fish Collagen/Glycoproteins’s Cosmetic Benefits/Uses

This ingredient brings two key actions to skin care formulas.

  • Humectant: attracts moisture from the environment and binds it to the skin surface helping to keep skin hydrated, soft and visibly plump
  • Skin Conditioning: forms a breathable film that smooths texture, improves elasticity and leaves skin feeling silky

Who Can Use Fish Collagen/Glycoproteins

Because it acts mainly as a lightweight humectant Fish Collagen/Glycoproteins generally suits all skin types. Dry and mature skin benefit most from its moisture-binding and smoothing properties while oily or combination skin usually tolerates it well since it absorbs without a heavy residue. Sensitive skin can also use it as the ingredient is considered gentle though anyone with a known fish allergy should avoid it entirely.

Fish Collagen/Glycoproteins is sourced from fish cartilage so it is not suitable for vegans or strict vegetarians. Pescatarians may find it acceptable depending on personal preference.

Current research shows no specific risks for pregnant or breastfeeding women when applying Fish Collagen/Glycoproteins topically, but this is not medical advice and anyone who is expecting or nursing should confirm product choice with a doctor to be safe.

The ingredient does not increase photosensitivity so there is no added risk of sunburn after application. It is also fragrance-free by nature which makes it less likely to irritate reactive skin.

Potential Side Effects/Adverse Reactions

Responses to topical Fish Collagen/Glycoproteins vary from person to person. The issues below are possible yet uncommon when the ingredient is formulated and used as intended.

  • Allergic reaction in individuals with fish or seafood allergies
  • Localized redness or itching
  • Mild stinging on very compromised or broken skin
  • Rare clogged pores in extremely acne-prone skin

If any of these reactions occur stop using the product and consult a healthcare professional.

Comedogenic Rating

Rating: 1/5. Fish Collagen/Glycoproteins is mainly a water-soluble mix of small peptides and glycoproteins that does not leave an oily film, so it has little tendency to block pores. Its slight film-forming action can occasionally trap oil on very congested skin but this is rare.

Generally considered suitable for those prone to acne or breakouts.

Keep in mind that the overall formula matters more than any single ingredient. Heavy oils, waxes or high silicone levels in the same product can raise the final comedogenic potential.

Summary

Fish Collagen/Glycoproteins acts as a humectant and skin-conditioning agent by drawing water into the surface layers, holding it there and laying down a light, flexible film that feels smooth and helps skin look plumper. The ingredient is appreciated in hydrating serums, sheet masks and lotion textures but it is still a niche option compared with plant-based humectants like glycerin or hyaluronic acid.

Topical use is regarded as safe for most people with the main caution being fish allergies. Side effects are uncommon and mild. As with any new product it is wise to perform a small patch test first to confirm personal tolerance.

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