Galloyl S-Tepidamorphus Gemmatus Oligopeptide-1 Sp: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Galloyl S-Tepidamorphus Gemmatus Oligopeptide-1 Sp?

Galloyl S-Tepidamorphus Gemmatus Oligopeptide-1 Sp is a lab-crafted peptide that carries a galloyl group, which is a plant-derived antioxidant moiety often found in tea leaves and oak bark. The peptide backbone is modeled after proteins naturally produced by Tepidamorphus gemmatus, a heat-loving microorganism discovered in geothermal springs. When scientists noticed the organism’s remarkable ability to protect its cellular proteins from high temperatures, they isolated short chains of its amino acids, then bonded them with galloyl to boost stability and antioxidant power.

Commercial production starts with a controlled fermentation of Tepidamorphus gemmatus to obtain the base peptide. The extracted peptide is then purified, reacted with plant-sourced gallic acid to add the galloyl group, and finally spray-dried into a fine powder for easy use in cosmetic labs. Since its introduction to the beauty industry in the late 2010s, formulators have included it in lightweight serums, overnight masks, scalp tonics, leave-in conditioners, age-defying creams and barrier-support moisturizers thanks to its multitasking profile.

Galloyl S-Tepidamorphus Gemmatus Oligopeptide-1 Sp’s Cosmetic Benefits/Uses

This peptide brings several perks to both skin and hair formulas

  • Hair conditioning: helps smooth the cuticle, adds softness and reduces breakage so strands feel silkier and look shinier
  • Skin conditioning: supports a softer, more supple feel while improving overall texture and bounce
  • Skin protecting: supplies antioxidant support that can help defend the skin surface against everyday environmental stressors such as pollution and UV-induced free radicals

Who Can Use Galloyl S-Tepidamorphus Gemmatus Oligopeptide-1 Sp

This multitasking peptide is generally well tolerated by all skin types, from oily to dry and sensitive. Its lightweight texture and low oil content mean it will not weigh down oily or acne-prone complexions, while its conditioning benefits offer welcome softness to drier or mature skin. No specific skin type is considered unsuitable, though extremely reactive skin should always proceed with extra caution when trying any new ingredient.

The peptide is produced through microbial fermentation and the galloyl group is derived from plants, so no animal-derived raw materials are involved. That makes it a vegan and vegetarian friendly option in formulas that avoid animal testing and animal by-products.

Current data show no ingredient components that would raise special concerns for women who are pregnant or breastfeeding. Nevertheless this is not medical advice, and anyone expecting or nursing should have their health care provider review the full product formula before use.

Galloyl S-Tepidamorphus Gemmatus Oligopeptide-1 Sp does not increase photosensitivity. Daytime users can simply follow normal sun protection habits.

Potential Side Effects/Adverse Reactions

Individual responses to topical Galloyl S-Tepidamorphus Gemmatus Oligopeptide-1 Sp can vary. The points below outline potential side effects that could occur even though they are unlikely for most users when the ingredient is formulated and used correctly.

  • Redness and mild irritation
  • Transient stinging on very damaged or freshly exfoliated skin
  • Allergic contact dermatitis in those sensitive to gallic acid derivatives
  • Scalp itchiness when used in high concentration hair products

If any adverse reaction appears discontinue use and seek guidance from a qualified health professional.

Comedogenic Rating

Rating: 0–1

Galloyl S-Tepidamorphus Gemmatus Oligopeptide-1 Sp is a small, water-soluble peptide that contains no heavy oils or waxes, so it does not tend to block pores. In most formulas it is used at low concentrations, typically under 2 percent, further reducing any clogging potential. Because the galloyl group is also lightweight and easily rinsed from the skin, buildup is unlikely. The main time pore congestion could occur would be if the peptide is blended into a very rich balm or cream where other ingredients, not the peptide itself, are the culprit.

Overall this ingredient is considered suitable for people who are prone to acne or breakouts.

If you notice a formula with this peptide also contains high levels of comedogenic oils like coconut or cocoa butter, remember the rating applies to the peptide alone, not the finished product.

Summary

Galloyl S-Tepidamorphus Gemmatus Oligopeptide-1 Sp acts as a multitasker that conditions hair, softens skin and supplies antioxidant protection. The peptide backbone helps bind moisture and improve texture while the galloyl group scavenges free radicals to shield surface cells from daily environmental stress. On hair the ingredient smooths the cuticle which translates into less frizz and more shine.

It is still a niche addition, most often found in forward-thinking serums, scalp tonics and lightweight moisturizers rather than mass-market lines, but its profile is gaining attention as brands look for vegan friendly biotech actives with multiple benefits.

Current safety data show low irritation risk and no known long-term hazards, making it a low-concern choice for most users. Even so, skin is personal, so doing a quick patch test when trying any new product containing this peptide is always a good idea.

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