Gallstone: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Gallstone?

Gallstone is a small, solid mass that forms in the gall bladders or bile ducts of cattle. Most stones are made mainly of cholesterol, while others contain calcium salts and small amounts of pigments. Centuries ago traditional medicine practitioners valued dried bovine gallstones for their perceived healing qualities, and early apothecaries sometimes ground them into skin salves. When modern cosmetic chemists began exploring animal-derived ingredients for their emollient and conditioning properties, the unique lipid profile of gallstone caught their attention.

To create a cosmetic-grade ingredient, harvested stones are carefully cleaned to remove any tissue, then dried at low temperatures. They are crushed into a fine powder, sieved to a uniform particle size and sterilised. The resulting powder is light brown to orange and has a mild earthy scent that disappears once blended into formulas.

Because gallstone is rich in sterols and fatty acids it slips smoothly into many topical products. You can find it in nourishing masks, anti-aging creams, recovery balms, spot treatments and luxury moisturisers where suppliers highlight it as a traditional, rare skin-conditioning agent.

Gallstone’s Cosmetic Benefits/Uses

When formulators add gallstone to a product the main goal is skin conditioning. Its natural lipids form a thin breathable film on the surface of the skin, helping to soften rough patches, reduce flakiness and improve overall texture. Regular use can leave the complexion feeling supple and looking more radiant, which is why it often appears in products aimed at mature or very dry skin.

Who Can Use Gallstone

Gallstone powder tends to suit normal, dry and mature skin types that benefit from an extra layer of lipids. Combination or oily complexions might find it too heavy since the rich sterols can sit on the surface and make shine or congestion more noticeable. Sensitive skin usually tolerates it, yet anyone with a known allergy to bovine proteins should avoid it.

Because gallstone is sourced from cattle it is not appropriate for vegans or vegetarians. Ethical or religious beliefs that restrict animal‐derived ingredients would also rule it out.

There is no specific evidence that topical gallstone poses a risk during pregnancy or breastfeeding. Even so, data are limited so this information is not medical advice and expecting or nursing mothers should confirm product safety with their healthcare provider before use.

The ingredient does not cause photosensitivity, so daylight exposure is not a concern. Its earthy scent dissipates once blended into a formula and does not linger on the skin.

Potential Side Effects/Adverse Reactions

Individual responses can vary. The points below outline potential side effects but most people will not encounter them when using a well-formulated product.

  • Allergic contact dermatitis
  • Clogged pores or breakouts in oily or acne-prone skin
  • Skin irritation from residual bile acids if purification was inadequate
  • Unwanted odor in the finished product if the raw material was poorly processed
  • Ethical discomfort or distress for users opposed to animal-derived ingredients

If any adverse reaction occurs stop using the product immediately and consult a qualified healthcare professional.

Comedogenic Rating

Rating: 3 / 5

Gallstone powder is rich in sterols and fatty acids that create an occlusive film on the skin. These heavier lipids can mix with sebum and dead cells, which raises the risk of blocked pores in some users. Because most formulas include it at low percentages and the particles sit mostly on the surface, the clogging potential is considered moderate rather than high.

People who are prone to acne or frequent breakouts may want to avoid products featuring gallstone or reserve them for occasional use only.

Formulation choices matter: combining the ingredient with lightweight emollients, exfoliating acids or non-pore-clogging oils can help lower the practical comedogenic impact.

Summary

Gallstone functions primarily as a skin-conditioning agent. Its mix of sterols and fatty acids forms a breathable lipid layer that softens rough spots, reduces flakiness and adds a subtle glow, making it attractive for dry or mature skin care lines.

The ingredient is niche rather than mainstream. Limited supply, ethical concerns about animal sourcing and the availability of plant-based alternatives keep it out of most mass-market formulas, yet it still appears in some high-end balms and heritage-inspired treatments.

Topical use is generally safe when the raw material is properly purified, with side effects limited to rare allergies or pore congestion in oily skin. As with any new product a quick patch test on a small area is the smartest way to check for personal compatibility before full-face application.

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