Glycereth-7/Ipdi Copolymer: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Glycereth-7/Ipdi Copolymer?

Glycereth-7/Ipdi Copolymer is a lab made polymer that links two well known building blocks: glycerin and isophorone diisocyanate (IPDI). First, natural glycerin is treated with ethylene oxide to create Glycereth-7, a short chain of seven repeating “oxyethylene” units that stays water loving. This piece is then reacted with IPDI, a ring shaped molecule often used in flexible coatings, to form long chains joined by safe urethane bonds. The result is a clear slightly viscous liquid or soft solid that blends smoothly with both water and oils.

The cosmetic world began using this copolymer in the late 1990s when chemists looked for ingredients that could form weightless films on skin without the tacky feel of older resins. Its balanced water-oil nature, mildness and low odor made it a handy alternative to heavier waxes and petrolatum based film formers.

Production happens in closed stainless steel reactors. First, purified glycerin is ethoxylated under controlled pressure and temperature until a seven-unit average chain length is reached. After cooling, IPDI is slowly added with gentle stirring. Catalysts help link the molecules while strict temperature control prevents yellowing. The mixture is then neutralized, filtered and standardized to a set viscosity so formulators get a consistent product every time.

You will usually spot Glycereth-7/Ipdi Copolymer in leave-on products that need a light protective layer such as facial serums, sheet mask essences, moisturizing sprays, color-stay makeup, hair smoothing creams, anti-aging lotions and hand sanitizing gels. Its ability to stay clear and flexible also makes it common in styling gels and brow setters.

Glycereth-7/Ipdi Copolymer’s Cosmetic Benefits/Uses

This multitasker brings several perks to modern formulas:

  • Film forming – Creates a thin breathable coat that locks in moisture, helps active ingredients stay on the skin or hair and improves wear time of makeup
  • Skin conditioning – Adds a soft non greasy feel, reduces water loss and can make skin feel smoother right after application
  • Viscosity controlling – Gives products a silky flow, keeps particles evenly suspended and prevents watery layers from separating

Who Can Use Glycereth-7/Ipdi Copolymer

This copolymer is generally well suited for all skin types. Dry and mature skin appreciate its moisture locking film while combination and oily skin benefit from its weightless feel that does not add extra grease. Sensitive skin usually tolerates it because it is non reactive and free of known sensitizers, though rare individuals who react to polyurethanes should be mindful.

The raw materials are either plant based glycerin or fully synthetic chemicals, and no animal derived components are required during manufacture so Glycereth-7/Ipdi Copolymer can fit vegan and vegetarian lifestyles. Brands that market to these groups typically confirm their glycerin source is vegetable.

The ingredient is considered low risk for those who are pregnant or breastfeeding thanks to its large molecular size and minimal skin penetration. This is not medical advice and anyone expecting or nursing should show the full product ingredient list to a health professional before use just to be safe.

It does not make skin more sensitive to sunlight and will not interfere with SPF ingredients. It also plays nicely with most actives including retinoids and acids because it is chemically stable and pH flexible.

Potential Side Effects/Adverse Reactions

Responses to topical Glycereth-7/Ipdi Copolymer differ from one person to the next. The points below list potential reactions only; when the ingredient is used correctly most people will not notice any problems.

  • Mild skin irritation such as redness or stinging in very sensitive users
  • Itching or contact dermatitis in individuals allergic to polyurethane type materials
  • Transient eye irritation if the product accidentally gets into the eyes
  • Build up on hair strands leading to a weighed down feel if used in high concentration leave-in products

If any negative reaction occurs stop using the product and seek guidance from a qualified healthcare professional.

Comedogenic Rating

Rating: 0 / 5

Glycereth-7/Ipdi Copolymer earns a zero because its large polymer chains sit on the surface of skin rather than seeping into pores and the ingredient is lightweight without the oily residue that usually triggers blockages. It is water dispersible, highly purified and lacks fatty acids that can feed acne bacteria.

That makes it generally suitable for people who are prone to acne or breakouts.

One point worth noting is that very high percentages in leave-on formulas could mix with other heavier ingredients and create an occlusive layer, so overall product composition matters more than the copolymer itself.

Summary

Glycereth-7/Ipdi Copolymer works as a film former, skin conditioner and viscosity controller. Its balanced water-oil structure lets it spread a barely-there film that locks in moisture and keeps active ingredients in place, the glycereth portion attracts water for softness while the IPDI links give strength and flexibility, and its polymer network thickens formulas just enough for a smooth glide.

It is a niche yet useful ingredient, most common in lightweight serums styling gels and long-wear makeup rather than everyday creams so you may or may not spot it on every label.

Safety reviews place it in the low-risk category with minimal irritation reports. As with any new cosmetic, patch test when trying a product that contains it to ensure personal compatibility.

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