Glyceryl Arachidonate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Glyceryl Arachidonate?

Glyceryl Arachidonate is an ester formed when glycerin, the familiar moisturizer derived from plant oils, links with arachidonic acid, a 20-carbon fatty acid that naturally occurs in some vegetable and marine oils. The result is a silky lipid that blends the skin-cushioning feel of glycerin with the richness of a long-chain fatty acid.

The ingredient first drew interest in the late 1990s when formulators searched for plant-based substitutes for animal-derived fats that could both soften skin and stabilize complex creams. By reacting purified glycerin with sustainably sourced arachidonic acid in a controlled heat-driven esterification process, chemists created Glyceryl Arachidonate in a high-purity form suitable for cosmetics. The finished material is a pale, almost odorless oil that disperses well in both water-in-oil and oil-in-water systems.

Today you will spot Glyceryl Arachidonate in a range of products such as facial moisturizers, night creams, anti-aging serums, wash-off masks, body lotions and hair conditioners where it lends slip, comfort and formula stability.

Glyceryl Arachidonate’s Cosmetic Benefits/Uses

This multitasking lipid supports both the feel and stability of modern formulas.

  • Emollient: Adds a soft, cushiony finish that helps smooth rough patches, reduces flakiness and leaves skin feeling supple
  • Emulsifying: Helps oil and water mingle so creams stay uniform, resist separation and spread evenly with a light touch

Who Can Use Glyceryl Arachidonate

Glyceryl Arachidonate is generally friendly to most skin types. Its lightweight emollient nature suits dry, normal and combination skin that crave softness without heaviness. Oily or acne-prone skin may wish to proceed with caution because the fatty acid backbone can feel rich and might contribute to clogged pores for those already prone to congestion.

The molecule is synthesized from plant-derived glycerin and arachidonic acid sourced from botanical or algae oils, so it is suitable for vegans and vegetarians when the manufacturer confirms plant origin.

Pregnant and breastfeeding individuals can typically use products containing Glyceryl Arachidonate as it is not known to penetrate deeply or act hormonally. This is not medical advice and anyone expecting or nursing should run any skincare choice past a qualified healthcare provider to be safe.

The ingredient is not photosensitizing, meaning it will not make skin more reactive to sunlight. It also plays nicely with most other common skincare actives, so layering is rarely a problem.

Potential Side Effects/Adverse Reactions

Responses to topical Glyceryl Arachidonate vary from person to person. The effects listed below are possible yet unlikely for the average user when the ingredient is properly formulated and used as directed.

  • Mild skin redness or irritation
  • Temporary stinging on compromised or freshly exfoliated skin
  • Increased oiliness or breakthrough shine on very oily skin
  • Blocked pores or comedones in individuals prone to acne
  • Allergic contact dermatitis in those sensitive to fatty acid esters

If any of these reactions occur discontinue use and consult a healthcare professional for personalized guidance.

Comedogenic Rating

Rating: 2 / 5

Glyceryl Arachidonate is an esterified lipid that feels lighter than straight plant oils yet still delivers fatty acid richness. Its molecular size and partial polarity let it absorb without forming an occlusive film but the arachidonic acid portion can linger in pores, nudging the rating slightly above truly non-comedogenic materials. Formulas using it at low levels and balanced with lightweight humectants show minimal clogging in consumer evaluations.

Those with acne-prone or very oily skin may prefer to avoid it while normal, dry and combination types generally experience no issues.

Concentration and product type matter: below roughly 5 percent in fluid lotions its pore-blocking risk drops further.

Summary

Glyceryl Arachidonate serves as an emollient that smooths rough spots and a co-emulsifier that keeps oil and water perfectly mixed. It does this by pairing glycerin’s water-loving head with arachidonic acid’s oil-loving tail, giving products a silky slip and long-lasting uniformity.

Although it is not a blockbuster ingredient found in every drugstore cream, formulators value its plant origin and elegant skin feel so it appears in select mid to high-end moisturizers serums and hair treatments.

Safety data show a low rate of irritation or allergy and no systemic concerns. As with any new skincare ingredient a brief patch test before full use is the safest route for sensitive skin.

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