Glyceryl Glycyrrhetinate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Glyceryl Glycyrrhetinate?

Glyceryl glycyrrhetinate is an ester that links glycyrrhetinic acid, a soothing compound found in licorice root, with glycerin, a naturally hydrating alcohol derived from plant oils. By joining these two well known materials chemists created a molecule that mixes easily with both water and oil, giving it special value in skin care formulas. Licorice has been prized in beauty rituals for centuries due to its calming properties, yet it was not until the late twentieth century that laboratories refined glycyrrhetinic acid and combined it with glycerin to improve its stability and skin feel. The ingredient is produced through an esterification process: purified glycyrrhetinic acid reacts with glycerin under controlled heat then is purified further to remove any by products. Thanks to its balanced structure Glyceryl glycyrrhetinate shows up in a wide range of products such as lightweight serums, rich creams, after sun lotions, sheet masks, scalp tonics and anti aging moisturizers where a smooth, even texture is critical.

Glyceryl Glycyrrhetinate’s Cosmetic Benefits/Uses

In formulas this ingredient shines for one main reason

  • Emulsifying: It helps blend water and oil phases into a stable, uniform mixture so creams and lotions stay smooth, resist separation and feel pleasant on the skin

Who Can Use Glyceryl Glycyrrhetinate

This ingredient suits most skin types, including dry, normal, combination and sensitive skin, because its emulsifying role does not leave a heavy or greasy residue. Oily or acne-prone complexions can generally tolerate it as well since it is lightweight and helps keep formulas evenly blended, though very oil-sensitive users may prefer lower concentrations.

Glyceryl glycyrrhetinate is sourced from licorice root and plant-derived glycerin, so it is considered suitable for vegans and vegetarians. No animal-derived substances or by-products are typically used during its production.

Current data does not flag any special risks for women who are pregnant or breastfeeding when the ingredient is used topically at cosmetic levels. This is not medical advice and anyone who is pregnant or nursing should check with a healthcare professional before introducing new skincare products.

The molecule does not increase photosensitivity, so sun exposure concerns are minimal beyond normal daily SPF recommendations.

Potential Side Effects/Adverse Reactions

Reactions to topical Glyceryl glycyrrhetinate differ from person to person. The following points describe potential though uncommon issues; most users will not notice these effects when the ingredient is properly formulated and used.

  • Mild skin irritation such as redness or stinging
  • Itching or dryness if skin is already compromised
  • Allergic contact dermatitis in individuals sensitive to licorice-derived compounds
  • Eye irritation if the product accidentally migrates into the eyes

If any adverse reaction occurs discontinue use and consult a qualified healthcare professional for guidance.

Comedogenic Rating

Rating: 1/5

Built from non-comedogenic glycerin and lightweight glycyrrhetinic acid, Glyceryl glycyrrhetinate is present at low levels and sits at the water-oil interface rather than in pores, so its clogging potential is minimal.

Most acne-prone users can use it without added breakout risk.

Remember that the full formula, not just one emulsifier, decides whether a product will feel heavy or congestive.

Summary

Glyceryl glycyrrhetinate stabilises emulsions so creams stay silky, plus its licorice root heritage lends a mild calming boost. Although it is not a buzzy headline ingredient it earns steady behind-the-scenes use in everything from sunscreens to night creams thanks to dependable performance.

Safety data shows a low chance of irritation or pore issues, yet skin can be unpredictable so a quick patch test with any new product is a smart precaution.

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