Hesperidin: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Hesperidin?

Hesperidin is a plant-based compound naturally abundant in the white spongy part of citrus peels, especially oranges and lemons. Chemically it is a flavonoid glycoside, meaning it combines a flavonoid core with sugar units that improve its stability and solubility. Long valued in traditional diet and skin care made at home, hesperidin attracted the cosmetic world when early research showed it could soften skin and support its protective barrier.

Modern suppliers extract the compound from dried citrus peels using water or food-grade solvents, then purify it through filtration and crystallization. The result is a fine off-white powder that blends well into creams, lotions and serums. Today you will most often spot hesperidin in moisturizers, soothing masks, brightening emulsions, eye creams and after-sun products that aim to replenish the skin’s moisture and leave it feeling supple.

Hesperidin’s Cosmetic Benefits/Uses

In skin care formulas hesperidin works mainly as an emollient. As an emollient it fills in tiny gaps between skin cells, creating a smooth even surface that feels soft to the touch. This action helps reduce roughness, enhances flexibility and supports the skin’s natural barrier so moisture stays locked in for longer. Products enriched with hesperidin therefore leave the complexion feeling more comfortable and looking healthier.

Who Can Use Hesperidin

Because hesperidin is a light emollient it suits most skin types including dry, normal and combination. Oily or acne prone skin can use it too since the ingredient is not greasy and does not clog pores. People with very reactive or citrus allergies should be careful as the compound comes from citrus peel and could trigger a flare in those rare cases.

The ingredient is plant derived so products that rely on pure hesperidin without animal based additives fit vegan and vegetarian lifestyles.

Current research gives no sign that topical hesperidin poses a risk for pregnant or breastfeeding women. Still this article is not medical advice so anyone who is expecting or nursing should show the product to a qualified doctor before adding it to a routine.

Hesperidin does not make skin more sensitive to the sun and can be applied morning or night. It also plays nicely with common actives like niacinamide and hyaluronic acid.

Potential Side Effects/Adverse Reactions

Responses to topical hesperidin vary from person to person. The effects listed below are possible yet uncommon when the ingredient is used at normal levels in a well made cosmetic.

  • Redness or mild irritation
  • Itchy feeling in people allergic to citrus
  • Temporary stinging on cracked or broken skin
  • Contact dermatitis in very sensitive users

If any of these reactions occur stop using the product at once and seek advice from a healthcare professional if symptoms persist.

Comedogenic Rating

Rating: 0/5. Hesperidin is a water soluble flavonoid that does not form a heavy film or leave oily residues on the skin, so it has virtually no tendency to block pores. At the low concentrations used in cosmetics it remains light and non occlusive making it safe for acne prone or breakout prone skin. No data suggest the molecule oxidises into pore clogging byproducts and it rinses away easily, further supporting its non comedogenic profile.

Because the ingredient is often paired with lightweight humectants and gentle emulsifiers, finished products that feature hesperidin rarely feel greasy or thick which keeps the overall formula friendly for congested skin types.

Summary

Hesperidin is valued in skincare for its emollient action that smooths rough patches, fills microscopic gaps between cells and strengthens the skin barrier so moisture stays put. By nestling between corneocyte layers it improves flexibility and leaves the complexion soft and comfortable.

Although not as famous as hyaluronic acid or vitamin C, this citrus derived flavonoid enjoys quiet popularity in moisturizers, eye creams and after sun lotions aimed at boosting suppleness without heaviness. Its plant origin, vegan suitability and low irritation risk make it an attractive choice for formulators seeking a gentle feel good addition.

Topical use is considered safe for most people with only rare reports of sensitivity, mainly in those with citrus allergies. As with any new ingredient it is wise to perform a quick patch test when trying a product that contains hesperidin just to be on the safe side.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search