Hexyl Nicotinate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Hexyl Nicotinate?

Hexyl nicotinate is an ester formed when nicotinic acid, a form of vitamin B3, reacts with hexyl alcohol, a fatty alcohol often sourced from natural plant oils. The result is an oily liquid that mixes well with other cosmetic ingredients and feels smooth on the skin. First explored in the mid-20th century for its warming effect in rubs and balms, it soon found a home in beauty formulas thanks to its softening qualities and its ability to cut down on static in hair and fabric. Today it is produced in a controlled lab setting where nicotinic acid and hexyl alcohol are combined under heat and then purified for safety. You will most often spot it in leave-on products such as face and body lotions, night creams, hair serums, masks and anti-aging blends where a silky touch and even spread are key.

Hexyl Nicotinate’s Cosmetic Benefits/Uses

In skin and hair care formulas hexyl nicotinate brings two main perks

  • Antistatic: Helps reduce the buildup of static electricity on hair strands and on the surface of fabrics, leading to smoother looking hair and less flyaway
  • Emollient: Forms a light film that fills in tiny gaps on the skin’s surface so it feels softer and more supple while also helping the product glide on evenly

Who Can Use Hexyl Nicotinate

Hexyl nicotinate is gentle enough for most skin types, including normal, dry and combination skin. Oily or acne-prone users usually tolerate it well because it forms a light, non-greasy film that does not clog pores. Sensitive skin can also benefit, though anyone with a history of reacting to vitamin B3 derivatives should keep an eye on how their skin feels when trying it for the first time.

The ingredient is typically produced in a lab from plant-derived sources, so it is suitable for vegans and vegetarians.

Current research shows no specific risks for pregnant or breastfeeding women when hexyl nicotinate is used topically in cosmetic amounts. This is not medical advice, and anyone who is expecting or nursing should still check with a healthcare professional before adding new products to their routine.

Hexyl nicotinate is not known to cause photosensitivity, so daytime use does not require extra sun protection beyond a normal sunscreen habit.

Potential Side Effects/Adverse Reactions

Side effects and reactions to topical hexyl nicotinate can vary from person to person. The points below list potential issues, but most users will not experience them when the ingredient is formulated and used correctly.

  • Transient warmth or flushing
  • Mild redness in treated areas
  • Temporary tingling or stinging
  • Itching or irritation in sensitive skin
  • Rare allergic reaction such as hives or swelling

If any of these effects occur stop using the product and consult a healthcare professional.

Comedogenic Rating

Rating: 1/5. Hexyl nicotinate is an ester with a light, oily texture that spreads easily and absorbs without leaving a heavy residue. Its molecular size and structure make it less likely to lodge inside pores compared with thicker plant butters or waxes, so it rarely triggers blockages that lead to breakouts. Most acne-prone users can safely use products containing this ingredient, though results always depend on the full formula and individual skin.

Because it is typically used at low concentrations, its overall impact on pore clogging is minimal. When combined with other low-comedogenic ingredients, it is generally considered a safe choice for those watching their pores.

Summary

Hexyl nicotinate serves two key roles in cosmetics: it works as an antistatic agent to keep hair and fabrics smoother and as an emollient that softens skin by forming a thin, flexible film on the surface. It achieves these effects thanks to its fatty alcohol end, which conditions, and its nicotinic acid end, which helps the molecule blend and spread evenly.

You will not see it topping ingredient trend lists, but formulators appreciate its reliable performance in lotions, creams and serums where a silky feel is needed without heaviness.

Overall safety is high, with only mild transient warmth or redness reported in a small number of users. While reactions are uncommon, it is wise to patch test any new product containing hexyl nicotinate so your skin can tell you if it is a match.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search