What Is Hyaluronic Acid/Polyglutamic Acid Crosspolymer?
Hyaluronic Acid/Polyglutamic Acid Crosspolymer is a network made by linking two well loved hydrators, hyaluronic acid and polyglutamic acid, together with the amino acid lysine. The result is a larger, sponge like molecule that can sit on skin and hold water for longer than either ingredient on its own. Both hyaluronic acid and polyglutamic acid come from natural fermentation of plant sugars or friendly bacteria, giving the finished material a bio based origin.
The idea of crossing these two molecules grew out of the search for longer lasting moisture and a lightweight feel. Labs began testing blends in the late 2010s, then found that adding lysine helped lock the chains into a three dimensional shape. A gentle coupling agent steps in during production to guide the bonds, after which the mixture is purified and dried into a fine powder ready for formulas.
Because the crosspolymer can bind water and also help balance oil, brands add it to many leave on products. You will spot it in hydrating serums, oil control gels, sheet masks, soothing after sun lotions, anti aging creams, lightweight daily moisturizers and makeup primers that aim to smooth skin texture.
Hyaluronic Acid/Polyglutamic Acid Crosspolymer’s Cosmetic Benefits/Uses
This multi tasker brings several perks to a formula and to the skin
- Anti-Sebum: The mesh structure can absorb excess oil on the surface helping skin look fresher and reducing midday shine
- Antioxidant: It helps mop up free radicals from the environment which can slow the look of early aging and keep skin tone more even
- Humectant: Like a magnet for moisture it draws water from the air and deeper layers then holds it at the surface giving skin a plump supple feel
- Skin Conditioning: By smoothing rough patches and softening the outer layer it makes skin feel silky and prepares it for makeup
- Skin Protecting: The breathable film it forms acts as a light shield against pollution particles and minor irritants lowering the chance of dryness or redness
Who Can Use Hyaluronic Acid/Polyglutamic Acid Crosspolymer
This crosslinked hydrator is gentle enough for almost every skin type. Dry and dehydrated skin benefit from the long-lasting moisture, while oily and combination skin appreciate the lightweight, sebum-balancing feel. Sensitive skin usually tolerates it well because the molecule sits on the surface rather than diving deep, lowering the risk of irritation. Only those with a known allergy to any of the source materials should avoid it.
The ingredient is produced by fermenting plant sugars or friendly bacteria, then linking the polymers with the amino acid lysine, so it is free from animal derivatives and is suitable for both vegans and vegetarians.
Current data shows no reason for healthy pregnant or breastfeeding women to avoid products containing Hyaluronic Acid/Polyglutamic Acid Crosspolymer. Still, this is not medical advice and anyone who is pregnant or nursing should check with a healthcare professional before adding new products to a routine.
The polymer does not make skin more sensitive to sunlight, so it is not considered photosensitizing. Standard daytime SPF use is still recommended for overall skin health.
Potential Side Effects/Adverse Reactions
Responses to topical Hyaluronic Acid/Polyglutamic Acid Crosspolymer differ from person to person. The issues listed below are only potential outcomes and are unlikely for most users when the ingredient is used correctly in a well-formulated product.
- Mild redness or warmth
- Transient stinging or tingling on very sensitive skin
- Rare allergic contact dermatitis in individuals sensitive to hyaluronic acid, glutamic acid derivatives or fermentation by-products
- Occlusive-related breakouts if layered with heavy oils on acne-prone skin
If irritation or any unexpected reaction occurs discontinue use and consult a qualified healthcare professional
Comedogenic Rating
Rating: 0 / 5
Hyaluronic Acid/Polyglutamic Acid Crosspolymer is a large, water-loving molecule that stays on the skin’s surface and contains no oily or waxy components that could clog pores. Because it forms a breathable film and even absorbs excess sebum, it has virtually no tendency to create comedones. In rare cases, breakouts may appear if the polymer is combined with very heavy oils or butters in a formula, but this would be due to the other ingredients, not the crosspolymer itself.
Suitable for acne-prone or breakout-prone skin.
Summary
Hyaluronic Acid/Polyglutamic Acid Crosspolymer acts as a humectant, antioxidant, anti-sebum agent, skin conditioner and light protector. Its crosslinked mesh pulls water from the air and deeper layers then traps it at the surface for long-lasting hydration. The network also soaks up surplus oil, helping skin look matte while the glutamic acid portion offers antioxidant activity that neutralizes free radicals. By forming a silky, flexible film, it smooths texture and shields skin from pollution particles without feeling heavy.
Although still newer than classic hyaluronic acid, the ingredient is gaining traction in serums, gels and masks aimed at people who want strong hydration with a weightless feel. Brands appreciate its plant-derived origin and multi-tasking nature, so its presence on ingredient lists is steadily rising.
Current research shows it is low-risk for irritation or pore clogging, making it safe for most users. As with any new skincare product, a simple patch test is wise to confirm personal compatibility.