Hydrogenated Sodium Cyclic Lysophosphatidic Acid: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Hydrogenated Sodium Cyclic Lysophosphatidic Acid?

Hydrogenated Sodium Cyclic Lysophosphatidic Acid is a modified phospholipid made from soy-derived lysophosphatidic acid. Chemists begin with natural soybean oil, isolate its phospholipids then remove one fatty acid chain to create lysophosphatidic acid. The remaining unsaturated chain is hydrogenated to make it more stable, after which the molecule is cyclized to form a five-membered phosphate ring and finally neutralized with a small amount of sodium. This careful sequence yields a salt that dissolves easily in water-based formulas and resists oxidation.

Phospholipids have been explored for skin care since the 1960s for their affinity with the skin’s natural barrier. The cyclic, hydrogenated version emerged more recently when formulators looked for a stable amphiphilic ingredient that could condition skin without the stickiness sometimes linked to traditional lecithin. Today it appears in lightweight moisturizers, anti-aging serums, sheet masks, soothing lotions and leave-on treatments where a silky, hydrated finish is desired.

Hydrogenated Sodium Cyclic Lysophosphatidic Acid’s Cosmetic Benefits/Uses

Its primary role in cosmetics is skin conditioning. By mimicking the structure of the skin’s own lipids it helps replenish the protective moisture barrier, supports smoother texture, enhances softness and can improve the spreadability of a formula so actives are distributed more evenly across the face.

Who Can Use Hydrogenated Sodium Cyclic Lysophosphatidic Acid

This soy-derived phospholipid is generally well tolerated by all skin types including dry, normal, combination, oily and sensitive skin. Its lightweight texture and barrier-supporting action make it helpful for dryness while its non-occlusive finish avoids heaviness that can bother oily or acne-prone complexions. Only those with a confirmed allergy to soy or phosphates should steer clear since the molecule originates from soybean oil and could theoretically trigger a reaction in highly sensitive individuals.

The ingredient is plant sourced and contains no animal by-products so it is suitable for vegans and vegetarians. Production relies on vegetable oil processing rather than animal-derived lipids commonly seen in traditional phospholipids.

Current safety data show no specific risks for pregnant or breastfeeding women when the ingredient is applied topically at cosmetic concentrations. That said this is not medical advice and anyone who is pregnant or nursing should review any new skincare product with a qualified healthcare provider before use.

Hydrogenated Sodium Cyclic Lysophosphatidic Acid does not make skin more sensitive to sunlight so it is not considered photosensitising. It can be used in both daytime and nighttime routines without extra sun precautions beyond regular sunscreen use.

Potential Side Effects/Adverse Reactions

Side effects from topical use of Hydrogenated Sodium Cyclic Lysophosphatidic Acid vary from person to person. The points below list potential reactions yet they are uncommon when the ingredient is formulated and used correctly.

  • Mild redness or irritation in users with very sensitive skin
  • Stinging on compromised or broken skin
  • Allergic contact dermatitis in individuals allergic to soy or phosphate compounds

If any of the above reactions occur discontinue use immediately and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 1 out of 5

Hydrogenated Sodium Cyclic Lysophosphatidic Acid is a lightweight phospholipid salt that blends easily into water based formulas and does not form a heavy film on the skin. Because it has a single, hydrogenated fatty acid chain and a highly polar phosphate ring it rinses cleanly during cleansing and is unlikely to block pores. The tiny chance of clogging comes from the fatty portion that could linger if a product is not removed properly, which is why it is rated a cautious 1 rather than a perfect 0.

Suitable for acne prone or breakout prone skin.

As with any ingredient its comedogenic impact also depends on the full formula. A rich cream packed with waxes may still clog pores even if this phospholipid on its own is low risk.

Summary

Hydrogenated Sodium Cyclic Lysophosphatidic Acid is a soy derived phospholipid that conditions skin by mimicking natural barrier lipids, holding water in the surface layers and helping other ingredients spread evenly. Its cyclic phosphate ring and hydrogenated chain give it good stability so it stays effective over time.

The ingredient is still a bit of an insider pick rather than a household name but its use is growing in modern lightweight serums, gels and masks that aim for a soft hydrated finish without heaviness.

Current research shows it to be very safe for topical use with a low allergy rate and virtually no irritation for most users. As with any new skin care ingredient it is wise to do a quick patch test when trying a product that contains it just to be on the safe side.

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