Hydrolyzed Myrica Gale Callus Culture Lysate Filtrate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Hydrolyzed Myrica Gale Callus Culture Lysate Filtrate?

Hydrolyzed Myrica Gale Callus Culture Lysate Filtrate is a plant-derived ingredient obtained from the bog myrtle shrub, also known as Myrica gale. Scientists start by taking a small sample of the plant’s tissue and growing it under sterile lab conditions to form a callus, which is a mass of undifferentiated cells packed with bioactive compounds. The callus is broken down, filtered and then hydrolyzed, a process that uses water to split larger molecules into smaller, more skin-friendly fragments. The final filtrate is a lightweight liquid rich in antioxidants, natural sugars and amino acids.

The beauty industry’s interest in plant cell cultures took off in the early 2000s as brands searched for sustainable ways to harness botanical actives without overharvesting wild plants. Myrica gale stood out because it thrives in harsh, boggy environments, forcing it to develop strong self-protective molecules that can also benefit skin. By using cell culture technology manufacturers can consistently produce the ingredient year-round while limiting environmental impact.

You will most often spot Hydrolyzed Myrica Gale Callus Culture Lysate Filtrate in serums, lightweight moisturizers, sheet masks, eye creams, after-sun gels and anti-aging treatments where a boost of hydration and antioxidant defense is desired.

Hydrolyzed Myrica Gale Callus Culture Lysate Filtrate’s Cosmetic Benefits/Uses

When added to skincare formulas this ingredient delivers two key functions that work together for healthier looking skin:

  • Antioxidant: The filtrate supplies polyphenols that help neutralize free radicals created by UV rays and pollution. This protective action supports a brighter tone and may reduce the appearance of premature lines and dullness
  • Humectant: Its natural sugars and amino acids draw water into the upper layers of the skin, enhancing immediate hydration, softening texture and improving the spreadability of the product

Who Can Use Hydrolyzed Myrica Gale Callus Culture Lysate Filtrate

This gentle ingredient works well for nearly all skin types including dry, oily, combination and sensitive skin because it hydrates without clogging pores or leaving a greasy feel. Those with extremely reactive or allergy-prone skin should still double-check the full product formula for other triggers, but the filtrate itself is considered non-sensitizing.

The material is entirely plant based and produced in a lab setting that does not involve any animal derivatives or by-products, making it suitable for both vegans and vegetarians.

Current research shows no specific concerns for women who are pregnant or breastfeeding. That said this information is educational only, and anyone expecting or nursing should have their healthcare provider review any skincare product before use to be on the safe side.

Hydrolyzed Myrica Gale Callus Culture Lysate Filtrate is not known to increase photosensitivity, so it can be used in morning or evening routines. Standard daytime sun protection is still recommended for overall skin health.

Potential Side Effects/Adverse Reactions

Side effects from topical Hydrolyzed Myrica Gale Callus Culture Lysate Filtrate vary from person to person. The points below illustrate potential outcomes, yet they remain uncommon when the ingredient is formulated and used correctly.

  • Mild redness or itching in individuals with botanical allergies
  • Transient stinging on skin that is already irritated or freshly exfoliated
  • Contact dermatitis if combined with other sensitizing ingredients the user cannot tolerate
  • Eye irritation if the product migrates into the ocular area

If any of these reactions occur discontinue use and consult a medical professional or dermatologist for guidance.

Comedogenic Rating

Rating: 0/5 – Hydrolyzed Myrica Gale Callus Culture Lysate Filtrate is an entirely water-based extract with no fatty acids or heavy waxes that could sit on the skin and block pores. Its molecules are small and hydrophilic so they disperse quickly in a formula and rinse away cleanly. Because it behaves more like a lightweight humectant than an oil it is highly unlikely to trigger blackheads or breakouts.

Suitable for acne-prone and congestion-prone skin.

As with any ingredient the finished product’s overall comedogenic potential depends on the entire formula so look at the full ingredient list if clogged pores are a concern.

Summary

Hydrolyzed Myrica Gale Callus Culture Lysate Filtrate is valued for two main actions: it offers antioxidant protection by supplying polyphenols that shield skin from free-radical damage and it acts as a humectant by pulling water into the upper layers for a plumper smoother feel. Lab-grown plant cells make the supply sustainable while hydrolysis ensures the actives are small enough for better skin compatibility.

Although not yet a household name the ingredient is gaining quiet traction in next-generation serums eye gels and after-sun formulas where light texture and clean sourcing matter. Current data shows it is low risk for irritation or pore clogging making it a safe pick for most users. Still everyone’s skin is unique so patch test any new product that features this filtrate before applying it to your whole face.

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