Hydrolyzed Sisymbrium Irio Seedcake: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Hydrolyzed Sisymbrium Irio Seedcake?

Hydrolyzed Sisymbrium Irio Seedcake is a plant-derived ingredient made by breaking down the leftover seedcake of Sisymbrium irio, a member of the mustard family better known as London rocket. After the oil is pressed from the seeds, the remaining cake is treated with water, acids or enzymes to “hydrolyze” its proteins and other large molecules into smaller, skin-friendly fragments. The result is a water-soluble mix of amino acids, peptides and carbohydrates that can be easily blended into modern skin care.

Early interest in Sisymbrium irio came from its traditional use as animal feed and a soil-improving crop. Cosmetic chemists later noticed that the seedcake, once hydrolyzed, produced a lightweight film that helped shield skin from moisture loss. As a result, the ingredient started appearing in niche moisturizers and has since been adopted by larger brands looking for plant-based alternatives to synthetic protective agents.

You are most likely to find Hydrolyzed Sisymbrium Irio Seedcake in leave-on products that aim to support the skin barrier. Typical formulas include daily face and body lotions, hydrating serums, masks, after-sun gels and gentle baby creams. Because it is water-soluble it slots easily into both lightweight gels and richer emulsions.

Hydrolyzed Sisymbrium Irio Seedcake’s Cosmetic Benefits/Uses

In skin care this ingredient is valued for one core job

Skin protecting: The hydrolyzed proteins form an invisible, breathable layer that helps reduce transepidermal water loss, keeping skin hydrated for longer. This soft film also acts as a mild shield against everyday pollutants and irritants, making formulas feel comforting on sensitive or freshly exfoliated skin.

Who Can Use Hydrolyzed Sisymbrium Irio Seedcake

This plant based film former tends to suit most skin types. Dry or sensitized complexions benefit from its moisture locking shield while oily and combination skin appreciate that it is lightweight and non greasy. No specific concerns make it unsuitable for acne prone or mature skin.

Because it is fully plant derived and processed without animal by products it is acceptable for both vegans and vegetarians.

Current data shows no issues for women who are pregnant or breastfeeding when the ingredient is used in topical cosmetics; still this is not medical advice and anyone who is expecting or nursing should run all skincare choices past a qualified doctor just to be safe.

The ingredient does not increase photosensitivity so you can use it morning or night without heightened sun risk. It pairs well with most actives and preservatives commonly found in modern formulas.

Potential Side Effects/Adverse Reactions

Reactions to topical Hydrolyzed Sisymbrium Irio Seedcake vary from person to person. The following are potential side effects however they remain uncommon when the ingredient is properly formulated in a finished product.

  • Mild redness or itching in individuals sensitive to mustard family plants
  • Transient stinging if applied to freshly shaved or compromised skin
  • Rare cases of contact dermatitis due to individual allergy to seed proteins
  • Formula spoilage related irritation if the product is old or improperly stored

If any adverse reaction occurs stop use immediately and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 0–1 (practically non-comedogenic)

Hydrolyzed Sisymbrium Irio Seedcake is water soluble and contains mainly small peptides, amino acids and carbohydrates rather than heavy oils or waxes that can block pores. The ultra-light film it leaves on skin is breathable and easily rinsed away, giving it a very low likelihood of clogging follicles. This makes it suitable for people who are prone to acne or frequent breakouts.

As with most hydrolysates, formula context matters: pairings with rich butters or occlusive silicones could raise a finished product’s overall comedogenicity even though the seedcake extract itself stays low.

Summary

Hydrolyzed Sisymbrium Irio Seedcake serves mainly as a skin-protecting agent. Once applied its broken-down proteins form a light, invisible shield that slows water loss and buffers skin against everyday pollutants, leaving the surface feeling hydrated and comfortable.

While not yet a household name it is quietly gaining traction among brands looking for clean, plant-based alternatives to synthetic film formers. Its gentle nature, vegan origin and compatibility with most actives make it easy to slot into modern formulas aimed at sensitive or barrier-compromised skin.

Current safety data shows a very low risk of irritation or allergy and no evidence of systemic concerns. Still, skin is individual so it is wise to patch test any new product that features this or any other novel ingredient before full-face use.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search