Hydroxybutyric Acid/Hydroxypentanoic Acid Copolymer: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Hydroxybutyric Acid/Hydroxypentanoic Acid Copolymer?

Hydroxybutyric Acid/Hydroxypentanoic Acid Copolymer is a biodegradable polymer created when the natural soil bacterium Cupriavidus necator ferments a mix of D-glucose and propionic acid. During fermentation the microbe links two small molecules, 3-hydroxybutyric acid and 3-hydroxypentanoic acid, into long repeating chains that form a smooth plastic-like material. Once the polymer is harvested it is purified, dried and milled into a fine powder or tiny beads that cosmetic chemists can easily disperse in water or oil phases.

The beauty industry first became interested in this ingredient in the early 2000s when formulators were searching for eco-friendly substitutes for microplastics and petroleum-based thickeners. Because the copolymer is plant-sugar derived, fully biodegradable and certified by several green cosmetic standards, it quickly found a place in clean beauty lines.

You will usually spot Hydroxybutyric Acid/Hydroxypentanoic Acid Copolymer in rinse-off scrubs, clay masks, creamy cleansers, lightweight moisturizers, anti-aging serums and even some natural deodorants. Its mild polishing action, skin-softening feel and ability to fine-tune texture make it a flexible addition to both water-based and anhydrous formulas.

Hydroxybutyric Acid/Hydroxypentanoic Acid Copolymer’s Cosmetic Benefits/Uses

This multitasking polymer offers several helpful functions when blended into personal care products

  • Abrasive – The polymer can be engineered into uniform micro-particles that gently slough away dead skin cells and surface debris, giving skin a smoother brighter appearance without the harsh edges found in traditional exfoliating grains
  • Skin conditioning – Once hydrated the polymer films lightly over the skin surface, reducing roughness and leaving a soft non-greasy finish that enhances overall skin feel
  • Viscosity controlling – In lotions and gels its particulate structure boosts body and thickness, helping formulators achieve a rich yet spreadable texture and keeping pigments or actives from settling during shelf life

Who Can Use Hydroxybutyric Acid/Hydroxypentanoic Acid Copolymer

This ingredient is considered gentle enough for most skin types, including normal, dry, oily and combination. Its rounded biodegradable particles polish rather than scratch, making it generally safe for sensitive skin, though people with extremely reactive or broken skin might prefer chemical exfoliants that require no rubbing.

The copolymer is produced through bacterial fermentation of plant sugars with no animal-derived inputs, so it is suitable for both vegans and vegetarians.

Current safety data show no reproductive or developmental concerns, meaning products that use this polymer are unlikely to pose issues for pregnant or breastfeeding women. That said this is not medical advice and anyone who is pregnant or nursing should always review skincare choices with a healthcare professional first.

The polymer does not make skin more vulnerable to the sun and has no known effect on photosensitivity. It is non-volatile, fragrance-free and compatible with most other cosmetic ingredients, so formulators can add it to a wide range of routines without special precautions.

Potential Side Effects/Adverse Reactions

Responses to topical Hydroxybutyric Acid/Hydroxypentanoic Acid Copolymer can differ from person to person. The effects listed below are only potential outcomes and are unlikely to affect the average user when the ingredient is properly formulated and used as directed.

  • Transient redness or flushing
  • Mild stinging or tingling during or shortly after exfoliation
  • Dryness if used too frequently on already dehydrated skin
  • Micro-abrasion in users who apply excessive pressure while scrubbing
  • Rare allergic contact dermatitis to residual fermentation by-products

If any of these reactions occur stop use immediately and seek advice from a qualified medical professional.

Comedogenic Rating

Rating: 1/5

This fermentation-derived polymer is a solid particulate that sits on the skin surface rather than melting into pores. It contains no heavy oils or waxes and is fully biodegradable, so the chance of it trapping sebum or fostering bacterial growth is very low. A small fraction of users may experience clogging if the particles are not fully rinsed away, which is why it earns a conservative 1 instead of 0.

Overall the ingredient is considered suitable for acne-prone or breakout-prone skin when used in properly formulated products and removed with gentle cleansing.

Comedogenic risk mainly depends on the entire formula and how vigorously the scrub is massaged, not on the polymer itself.

Summary

Hydroxybutyric Acid/Hydroxypentanoic Acid Copolymer acts as a gentle abrasive, a skin-softening conditioning agent and a clean way to control viscosity. Uniform rounded particles polish away dull cells while the hydrated polymer leaves a silky film that smooths texture. Its solid structure also boosts thickness in gels and creams and helps keep pigments suspended.

Although it is not as famous as hyaluronic acid or retinol, the ingredient is quietly gaining traction in eco-conscious exfoliants cleansers and lightweight moisturizers thanks to its biodegradable origin and versatile feel.

Current data show it is low risk for irritation, sensitization or systemic toxicity, making it a safe choice for most users. As with any new skincare product a short patch test on a small area is still wise before full-face use.

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