Hydroxydodecyl Hydroxyethyl Ethylenediamine/Methyl Acrylate Dendrimer: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Hydroxydodecyl Hydroxyethyl Ethylenediamine/Methyl Acrylate Dendrimer?

Hydroxydodecyl Hydroxyethyl Ethylenediamine/Methyl Acrylate Dendrimer is a lab engineered polymer built in a branching, tree like structure called a dendrimer. Chemists start with ethylenediamine, then add methyl acrylate step by step, followed by monoethanolamine, finishing with epoxydodecane to cap the outer “branches.” This careful, layer by layer process lets scientists control the size and performance of the molecule so it behaves predictably in a finished formula.

The ingredient has no natural source; it was created to solve formulating challenges in modern skin and hair care. Dendrimers first caught cosmetic chemists’ attention in the late 1990s for their ability to carry active ingredients and improve texture. Over time, this particular version proved especially useful for getting oil and water to mix and for lifting away dirt without stripping skin.

You are most likely to find Hydroxydodecyl Hydroxyethyl Ethylenediamine/Methyl Acrylate Dendrimer in rinse off cleansers, micellar waters, facial wipes, two phase makeup removers, lightweight lotions, hair masks and some long wear sunscreens where stable emulsions are a must.

Hydroxydodecyl Hydroxyethyl Ethylenediamine/Methyl Acrylate Dendrimer’s Cosmetic Benefits/Uses

In formulas this dendrimer plays more than one helpful role:

  • Cleansing: Its branched structure wraps around oils, makeup and daily grime so they can be rinsed away easily. This gives cleansers a thorough yet gentle washing action that leaves skin feeling soft rather than tight.
  • Emulsifying: It helps water based and oil based ingredients stay evenly mixed, preventing separation in the bottle and ensuring every pump or scoop delivers the same balanced blend of actives.

Who Can Use Hydroxydodecyl Hydroxyethyl Ethylenediamine/Methyl Acrylate Dendrimer

This ingredient is generally well tolerated by most skin types, including oily, combination and sensitive, because it is non stripping and has a low irritation profile. Very dry or eczema-prone skin might want an extra layer of moisture afterward since the cleans­ing action can remove some surface lipids.

Because the dendrimer is fully synthetic and contains no animal derived materials it meets vegan and vegetarian standards.

Current safety data show no specific risks for women who are pregnant or breastfeeding when the ingredient is used in rinse off or leave on cosmetics. That said this is not medical advice and anyone expecting or nursing should have a quick chat with a doctor before adding new products, just to be safe.

It does not make skin more sensitive to sunlight so no special sun precautions are needed beyond the normal daily use of sunscreen.

Potential Side Effects/Adverse Reactions

Side effects from topical use of Hydroxydodecyl Hydroxyethyl Ethylenediamine/Methyl Acrylate Dendrimer vary from person to person. The issues listed below are only potential effects and are unlikely for the average user when the ingredient is formulated and used correctly.

  • Mild skin irritation such as redness or stinging
  • Transient dryness or tightness, especially on very dry skin
  • Allergic contact dermatitis in individuals sensitive to amine or acrylate groups
  • Eye irritation if the product accidentally gets into the eyes

If any of these reactions occur discontinue use and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 1/5. The dendrimer is a bulky, water-compatible molecule that sits on the surface only briefly in most rinse-off products and even in leave-ons it forms a light, non-occlusive film. It does not contain heavy oils or waxes that typically clog pores so the likelihood of it blocking follicles is very low. Suitable for those prone to acne or breakouts.

Because it is almost always paired with other low-residue surfactants and emulsifiers, the overall formula usually rinses clean without leaving pore-plugging remnants.

Summary

Hydroxydodecyl Hydroxyethyl Ethylenediamine/Methyl Acrylate Dendrimer acts mainly as a cleanser and emulsifier. Its branched structure traps oils, makeup and dirt so they wash away easily and its multiple functional groups grip both water and oil phases keeping them evenly blended. This polymer gives formulators a way to create clear micellar waters, stable two-phase removers and light lotions that feel elegant on skin.

It is still a niche ingredient compared with classic emulsifiers like polysorbates but is gaining quiet popularity in premium and K-beauty lines that value gentle cleansing and feather-light textures.

Current research shows a strong safety profile with low irritation and minimal comedogenic risk. As with any new cosmetic, perform a quick patch test when trying a product that contains this dendrimer for the first time just to be sure your skin agrees with it.

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