Hydroxyethyl Acrylamide: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Hydroxyethyl Acrylamide?

Hydroxyethyl Acrylamide is a lab made molecule that belongs to the acrylamide family. Chemists describe it as 2-Propenamide, N-(2-hydroxyethyl)- which means it has both an amide group and a small alcohol group. These two parts let it grab onto water and other ingredients, making it a handy helper in skin care formulas.

The ingredient was first explored in the late 20th century when researchers were searching for safer acrylamide alternatives that would not break down into unwanted by-products. Its friendly profile, easy handling and strong performance earned it a place in the cosmetic lab bench. Today it is made through a controlled reaction between acrylic acid and ethanolamine, followed by purification steps that strip away leftover starting materials. The result is a clear to pale yellow liquid or solid that blends smoothly into water-based products.

You are most likely to see Hydroxyethyl Acrylamide in moisturizers, sheet masks, hydrating serums, lightweight lotions and anti-aging gels. Brands use it in rinse-off items like cleansers as well as leave-on treatments where a smooth flexible film is helpful.

Hydroxyethyl Acrylamide’s Cosmetic Benefits/Uses

In skin care formulas Hydroxyethyl Acrylamide serves one key role

Binding: it links water and other ingredients together helping to form a uniform stable mixture. This keeps creams from separating, improves spreadability and leaves a soft weightless finish on the skin

Who Can Use Hydroxyethyl Acrylamide

Hydroxyethyl Acrylamide is generally well tolerated across most skin types. Its light water-binding nature means it works for dry complexions that need extra hydration and for oily or acne-prone skin that cannot handle heavy occlusives. People with very reactive or allergy-prone skin should still review ingredient lists carefully because any synthetic compound can trigger sensitivity in rare cases.

The molecule is produced entirely in a lab from acrylic acid and ethanolamine, both sourced from non-animal raw materials, so it is considered suitable for vegans and vegetarians.

There is no known mechanism by which Hydroxyethyl Acrylamide would harm pregnant or breastfeeding women when used topically in standard cosmetic concentrations. That said this is not medical advice and anyone who is pregnant or nursing should show the full ingredient list of any new product to a qualified healthcare professional before adding it to their routine.

The ingredient does not absorb UV light or make skin more prone to sun damage so it is not linked to photosensitivity. It also plays well with common actives like vitamin C, niacinamide and retinoids, making it easy to slot into most regimens.

Potential Side Effects/Adverse Reactions

Reactions to topical Hydroxyethyl Acrylamide are uncommon yet everyone’s skin is unique. The points below outline potential side effects that have been reported in isolated cases; most users will not experience them when the ingredient is included at the levels allowed in cosmetic formulas.

  • Mild skin irritation such as stinging or burning on application
  • Transient redness or warmth in the area of use
  • Contact dermatitis in individuals allergic to acrylamide derivatives
  • Eye irritation if the product is accidentally rubbed into the eyes
  • Delayed sensitization after prolonged or repeated exposure in very sensitive users

If any of these issues occur stop using the product and seek guidance from a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 0 out of 5. Hydroxyethyl Acrylamide is a small water-friendly molecule that does not contain heavy oils or waxes that can clog pores. It stays mostly on the surface as a thin flexible film and is used at very low concentrations, so it poses virtually no risk of blocking follicles. This makes it a comfortable option for acne-prone or breakout-prone skin. Because it is often paired with lightweight gel textures, it typically appears in formulas already targeted at those seeking non-greasy hydration.

Summary

Hydroxyethyl Acrylamide’s main job in cosmetics is binding. It locks water and other ingredients together, creating smooth stable emulsions that spread easily and feel weightless. By forming a clear flexible film it helps creams and gels keep their texture while adding a subtle boost of surface hydration.

Although it performs well, the ingredient is not a headline star like hyaluronic acid or niacinamide so its name rarely gets marketing attention. Formulators value it behind the scenes for its reliability and gentle profile.

Safety data show a low risk of irritation or allergy for most users. As with any new skincare product it is smart to patch test first to confirm personal tolerance.

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