Hydroxyethyl Ethylene Dipalmitamide: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Hydroxyethyl Ethylene Dipalmitamide?

Hydroxyethyl Ethylene Dipalmitamide is a lab-crafted lipid derived from palmitic acid, a fatty acid that naturally occurs in palm oil and other plant fats. Chemists bond two palmitic acid chains to a small ethylene backbone that has been modified with a hydroxyethyl group. This structure gives the molecule a buttery texture and an affinity for skin-like oils, making it useful in personal care.

The ingredient first appeared in cosmetic research during the late 1990s when formulators were looking for plant-based alternatives to animal-sourced skin conditioners. Because it can mimic parts of the skin’s own lipid barrier, Hydroxyethyl Ethylene Dipalmitamide quickly found a home in moisturizers and specialty creams.

Manufacturing starts with sustainably sourced palm or vegetable oil, which is purified to extract palmitic acid. The acid is then reacted with ethylene glycol under controlled heat and pressure, followed by esterification to attach the second palmitic chain. After purification the finished material is a soft waxy solid that melts at skin temperature.

You’ll most often see Hydroxyethyl Ethylene Dipalmitamide in rich face creams, overnight masks, anti-aging formulas and leave-on treatments designed to soothe dryness or support the skin barrier. It also appears in some hair conditioners where a light, non-greasy conditioning effect is desired.

Hydroxyethyl Ethylene Dipalmitamide’s Cosmetic Benefits/Uses

This ingredient serves one main purpose in skincare products

As a skin conditioning agent it helps soften and smooth the surface of the skin while reinforcing the natural lipid barrier. By filling in microscopic gaps between skin cells it reduces moisture loss leading to a more comfortable hydrated feel and a healthier looking complexion.

Who Can Use Hydroxyethyl Ethylene Dipalmitamide

This silky lipid suits most skin types, especially dry, sensitive and mature skin that benefit from extra barrier support. Normal and combination skin usually tolerate it well while very oily or acne prone skin might find rich formulas containing high levels of the ingredient a bit heavy.

Because it is derived from plant oils and involves no animal sourced materials Hydroxyethyl Ethylene Dipalmitamide is considered suitable for vegans and vegetarians.

No specific data flags the ingredient as unsafe for pregnant or breastfeeding women yet personal circumstances differ. This is not medical advice so anyone who is expecting or nursing should show the full product ingredient list to a healthcare professional before use.

The molecule does not make skin more reactive to sunlight and has no known influence on photosensitivity. It is also fragrance free and carries no natural color so it rarely interferes with other actives in a routine.

Potential Side Effects/Adverse Reactions

Responses to topical Hydroxyethyl Ethylene Dipalmitamide vary from person to person. The effects listed below are only potential issues that remain unlikely for the average user when the ingredient is formulated and used correctly.

  • Mild redness or stinging in very sensitive skin
  • Allergic contact dermatitis in individuals with a specific fatty acid sensitivity
  • Temporary clogged pores or breakouts when used in heavy formulas on oily skin
  • Greasy or sticky afterfeel if layered with multiple occlusive products

If any unwanted reaction occurs stop using the product and seek advice from a qualified healthcare provider.

Comedogenic Rating

Rating: 2 out of 5. Hydroxyethyl Ethylene Dipalmitamide is a fatty acid-based lipid that melts into the skin and can create a light occlusive film. While this helps lock in moisture it also means there is a mild chance of pore congestion, especially when the ingredient is used at higher levels in rich creams or layered with other heavy oils and butters. Most leave-on products include it at concentrations low enough to stay below the breakout threshold for many users. Still, those who are highly acne prone may prefer lighter formulas or use it only on drier areas.

Overall it is generally acceptable for breakout-prone skin but caution is advised if your skin clogs easily.

Formulation style matters: pairing the ingredient with lightweight humectants and non-occlusive silicones can keep the overall comedogenic load low.

Summary

Hydroxyethyl Ethylene Dipalmitamide is valued as a plant-derived skin conditioning agent that softens, smooths and reinforces the skin’s lipid barrier by filling tiny gaps between surface cells. Its buttery texture mimics natural sebum helping skin hold onto moisture for longer comfort.

It is not the most famous name in cosmetics yet it has a loyal niche following among formulators who want a vegan alternative to animal ceramides without the heaviness of pure plant butters. You will usually spot it in mid- to high-end moisturizers aimed at dryness relief or barrier repair.

Safety data show a low risk of irritation or sensitization and no links to hormonal or systemic effects. As with any new skincare ingredient it is smart to patch test a product before full-face use to make sure your skin agrees with it.

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