Hydroxylated Fullerenes: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Hydroxylated Fullerenes?

Hydroxylated Fullerenes start with fullerenes, the soccer ball shaped cages of carbon atoms often called buckyballs. Chemists attach multiple hydroxyl groups (OH) to the outside of these cages, turning the once oil loving molecule into one that mixes well with water based formulas. This change also makes the spheres more stable on skin and easier to blend into creams or gels.

Fullerenes were first isolated in the mid 1980s, attracting attention for their strength and ability to carry electrons. By the late 1990s researchers realized that adding hydroxyl groups reduced the risk of irritation while opening the door for skin care use. Today cosmetic grade Hydroxylated Fullerenes are produced in controlled reactors where purified fullerenes are stirred with hydrogen peroxide or another hydroxyl source, then filtered and dried to a fine powder.

You will most often see Hydroxylated Fullerenes in lightweight anti aging serums, brightening essences, sheet masks, acne spot treatments, moisturizers aimed at oily skin and some high end cleansers. Brands value the ingredient for its stability at room temperature and its ability to pair with both water and oil soluble actives.

Hydroxylated Fullerenes’s Cosmetic Benefits/Uses

This ingredient brings two key actions to a formula

  • Antimicrobial – The carbon cage can generate low level reactive oxygen species when exposed to light, helping limit the growth of bacteria on the skin surface. This supports clearer looking skin and extends the shelf life of the product itself.
  • Skin Conditioning – The hydroxyl groups attract and hold water, giving the ingredient mild humectant properties. It also scavenges free radicals, which can support a smoother, more even appearance over time.

Who Can Use Hydroxylated Fullerenes

Because Hydroxylated Fullerenes are water loving yet non-oily, they suit most skin types including oily, combination, normal and even sensitive skin that reacts to heavy textures. Extremely dry or compromised skin may need a richer occlusive on top since this ingredient delivers light hydration but not a sealing barrier.

The molecule is synthesized entirely from carbon sources in a lab with no animal by-products, so it is compatible with vegan and vegetarian lifestyles.

No published studies flag Hydroxylated Fullerenes as unsafe during pregnancy or breastfeeding. Still, this is not medical advice. Anyone who is pregnant or nursing should review any new skincare product with a physician to be sure it fits their individual needs.

The ingredient does not make skin more prone to sunburn. It can actually quench some free radicals formed by UV light, yet it is not a replacement for sunscreen.

Hydroxylated Fullerenes are odorless, colorless, stable at normal room light and show no known conflicts with common actives like retinoids or vitamin C, making them easy to layer within a routine.

Potential Side Effects/Adverse Reactions

Responses to topical Hydroxylated Fullerenes differ from person to person. The following outlines potential but unlikely reactions when the ingredient is formulated and used as intended

  • Mild stinging or warmth on application
  • Transient redness especially on highly sensitive skin
  • Dryness if used in high concentrations without an accompanying moisturizer
  • Contact dermatitis in individuals allergic to fullerene derivatives
  • Interaction with other reactive oxygen generating ingredients such as benzoyl peroxide potentially amplifying irritation

If any discomfort or persistent irritation occurs discontinue use immediately and consult a healthcare professional

Comedogenic Rating

Rating: 0-1 (non comedogenic)

Hydroxylated Fullerenes dissolve in water, sit lightly on skin and are typically used at low levels so they do not trap oil or debris in pores. The smooth carbon spheres lack the fatty chains that usually cause congestion and they rinse away without leaving a film.

This makes the ingredient suitable for people who are prone to acne or frequent breakouts.

No evidence suggests it oxidizes sebum or changes skin’s natural oil balance, keeping its clogging potential near zero.

Summary

Hydroxylated Fullerenes act as gentle antimicrobials and light skin conditioners. The carbon cage weakens surface bacteria while the attached hydroxyl groups draw in moisture and neutralize free radicals, supporting a clearer smoother look.

The ingredient is still a niche player found mostly in high end serums, masks and oil control creams because its production costs more than standard hydrators or preservatives, yet its stability and multi-tasking benefits keep interest growing.

Available data shows Hydroxylated Fullerenes are non irritating, non sensitizing and non comedogenic at cosmetic use levels. Even so, patch test any new product containing this ingredient to be safe.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search