Hydroxysultaines: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Hydroxysultaines?

Hydroxysultaines are mild surfactants that come from fatty acids found in plant oils such as coconut or palm. Chemically they belong to the betaine family but carry a sulfonate group that helps them stay gentle on skin while still lifting away dirt and oil. They were introduced to personal care labs in the early 1980s when formulators wanted an alternative to harsher sulfates. Production starts with a natural or plant based fatty acid that is reacted with dimethylaminopropylamine to form an amidoamine, then treated with sodium 3-chloro-2-hydroxypropane sulfonate to create the final amphoteric molecule. Because the process is water based and works at moderate temperatures it is considered relatively eco-friendly.

You are most likely to see hydroxysultaines in foaming products such as shampoos, body washes, bubble baths, hand soaps, facial cleansers, micellar waters and shaving creams. They can also appear in clay masks and exfoliating scrubs where a creamy foam is desired.

Hydroxysultaines’s Cosmetic Benefits/Uses

Formulators choose hydroxysultaines for several practical reasons.

  • Cleansing: The molecule loosens oil, sweat and makeup so they rinse away easily, leaving skin or hair feeling fresh without a stripped sensation.
  • Foam Boosting: It builds a rich stable lather that improves the sensory feel of a wash product and helps distribute active ingredients evenly.

Who Can Use Hydroxysultaines

Because hydroxysultaines are mild and nonstripping they suit most skin types including dry, oily and combination. Sensitive skin usually tolerates them well since the molecule is amphoteric and maintains a skin-friendly pH, yet people with highly reactive or broken skin should still monitor how they feel in case any cleanser feels too strong.

The ingredient is typically derived from plant oils and no animal by-products are added during manufacture so it is considered acceptable for vegans and vegetarians. Check the full product label if strict cruelty-free or palm-free sourcing is important to you because suppliers vary.

Current research shows no hormonal activity or systemic absorption concerns, so products containing hydroxysultaines are generally viewed as safe for pregnant or breastfeeding women. This is not medical advice and anyone who is expecting or nursing should run the product past a healthcare professional to be on the safe side.

Hydroxysultaines do not make skin more sensitive to sunlight so they are not linked to photosensitivity. They also rinse away cleanly which helps prevent buildup on scalp or skin. Overall the ingredient works in most daily wash formulas without special precautions.

Potential Side Effects/Adverse Reactions

Side effects and reactions to topical hydroxysultaines can vary from person to person. The points below list potential issues, but they are uncommon when the ingredient is used correctly in a well-formulated product.

  • Mild skin dryness if the formula does not include added moisturizers
  • Temporary eye irritation if the foam accidentally gets into the eyes
  • Rare allergic contact dermatitis in individuals already sensitized to surfactants
  • Scalp tightness for those prone to very dry or eczema-prone scalps

If any irritation or unexpected reaction occurs discontinue use and consult a healthcare professional.

Comedogenic Rating

Rating: 0 (non-comedogenic)

Hydroxysultaines are water-soluble surfactants that rinse off completely and leave no oily residue that could clog pores. Unlike fatty alcohols or heavy plant oils, their molecular structure does not sit on skin after use, so they do not create the occlusive film that can trap sebum and dead cells. For this reason they earn a score of 0.

Suitable for people who are prone to acne or frequent breakouts, especially in rinse-off cleansers and shampoos.

No published data links hydroxysultaines to comedones or fungal acne, and most formulations pair them with similarly low-risk ingredients which keeps overall pore-clogging potential minimal.

Summary

Hydroxysultaines act primarily as gentle cleansers and foam boosters. Their amphoteric nature lets them lift away dirt and oil while keeping skin’s pH close to neutral, which reduces dryness and helps leave hair or skin feeling soft yet refreshed. The sulfonate group stabilizes a rich lather that spreads active ingredients evenly and improves the sensorial feel of washes and shampoos.

While not a household name, hydroxysultaines are gaining popularity among formulators looking to replace sulfates in mild everyday cleansers. Consumers may not recognize the term on labels, but they benefit from its silky foam in many sulfate-free products.

Current research finds the ingredient safe for most users, with irritation or allergy reports being rare. As with any new skincare or haircare product, it is smart to perform a small patch test before full use to ensure personal compatibility.

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