Isobutyl Myristate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Isobutyl Myristate?

Isobutyl myristate is an ester created when myristic acid, a fatty acid most often taken from coconut or palm kernel oil, reacts with isobutyl alcohol. The finished molecule is clear, lightweight and oily to the touch, which makes it handy for personal care formulas that need slip without heaviness.

Chemists started using fatty acid esters like isobutyl myristate in the 1950s as a gentler alternative to mineral oils. Over time its silky feel, quick spread and low odor earned it a spot in many modern beauty products. Production still relies on a straightforward process: the two raw materials are heated with a catalyst, water is removed and the resulting ester is purified until it meets cosmetic grade standards.

You will most often see isobutyl myristate in lightweight facial and body moisturizers, makeup primers, foundations, sunscreens, cleansing oils, hair conditioners and masks that aim to leave skin or strands soft without a greasy after-feel.

Isobutyl Myristate’s Cosmetic Benefits/Uses

Formulators turn to this ingredient for more than one reason:

  • Skin conditioning: It coats the surface of skin with a thin protective layer that helps reduce moisture loss so skin feels smoother and looks more supple.
  • Emollient: Its silky texture fills in tiny gaps between skin cells giving products an elegant glide and leaving skin velvety rather than sticky or oily.

Who Can Use Isobutyl Myristate

Because it feels light yet still locks in moisture, isobutyl myristate suits normal, dry and combination skin. Very oily or easily congested complexions might find it a bit rich, which could lead to clogged pores if formulas are heavy or layered too often.

The ester is usually made from coconut or palm kernel oil so it is plant derived and fits most vegan and vegetarian routines. Those who avoid palm for environmental reasons can look for brands that use certified sustainable sources.

No evidence shows that isobutyl myristate enters the bloodstream in meaningful amounts, so it is generally viewed as safe for people who are pregnant or breastfeeding. This is not medical advice and anyone expecting or nursing should still check with a qualified doctor before starting new products.

The ingredient does not increase sun sensitivity and plays well with daily sunscreen. It is also odorless and free of common fragrance allergens, making it a friendly option for scent sensitive users.

Potential Side Effects/Adverse Reactions

Responses to topical isobutyl myristate differ from person to person. The points below list potential drawbacks that most users will not experience when the ingredient is used at normal cosmetic levels.

  • Clogged pores or acne flare ups
  • Mild skin irritation such as redness or itching
  • Contact allergy in people sensitive to fatty acid esters
  • Increased absorption of strong actives that may raise their irritation potential

If any discomfort or adverse reaction develops stop using the product and consult a healthcare professional if symptoms persist.

Comedogenic Rating

Rating: 3 out of 5

Like many myristate esters, isobutyl myristate can lodge in pores more easily than lighter oils or silicones. Its medium sized molecular structure offers good slip yet it can still mingle with sebum and dead cells, which can block follicles on skin that is already congestion prone. The rating can vary a little depending on how much is used in a formula and what other ingredients sit alongside it, but a mid-range score of 3 reflects a moderate likelihood of breakouts for those who are already acne prone.

People who struggle with frequent blackheads or pustules may want to limit use of products that list isobutyl myristate high on the ingredient list while those with normal, dry or combination skin generally tolerate it well.

Formulation factors such as inclusion of exfoliating acids, non occlusive humectants or lightweight emulsifiers can offset some of the clogging risk, so the final product matters as much as the raw material itself.

Summary

Isobutyl myristate is valued for two main jobs: keeping skin conditioned and acting as an emollient. It forms a soft, flexible film that slows water loss and fills in microscopic gaps between skin cells which leaves the surface feeling smooth and supple. Its lightweight velvety texture helps spreads creams, makeup and sunscreens easily without a heavy greasy after-feel.

The ingredient enjoys steady but not superstar status in cosmetic labs. It is popular enough to appear in a variety of moisturizers, primers and cleansers yet it does not have the name recognition of ingredients like hyaluronic acid or shea butter.

Safety profiles from ingredient suppliers and independent panels rate isobutyl myristate as low risk for irritation or systemic toxicity when used at typical cosmetic levels. Still every skin is unique so it is wise to try any new product on a small patch of skin first to make sure it agrees with you.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search