Isocyclocitral: The Complete Guide To This Aroma Chemical

Curious about this ingredient? In this article we're explaining everything you need to know.
Updated on: August 15, 2025
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We verify all information on this page using publicly available standards from The International Fragrance Association (IFRA) and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Isocyclocitral?

Isocyclocitral is an aroma chemical first identified by flavour and fragrance researchers in the mid 1960s during studies on citral derivatives. It is produced today through carefully controlled chemical synthesis that starts with citral obtained from lemon grass or other citrus sources, followed by cyclisation and purification steps. Although trace amounts can occur naturally in certain plants, the material used in perfumery is manufactured in the laboratory to ensure both purity and reliable supply.

At room temperature the ingredient appears as a clear, free-flowing liquid that ranges from colourless to a faint straw tint. It sits comfortably in the middle of the volatility scale: not as heavy as many woody materials yet less fleeting than most citruses. This balance makes it practical for a wide range of formula types.

Isocyclocitral is readily available from the major fragrance suppliers, so perfumers can source it without difficulty. Its cost profile tends to be moderate, making it accessible for everyday functional products while still finding a place in fine fragrance where a crisp botanical effect is desired. The molecule is considered stable under normal handling conditions, giving it a long shelf life and dependable performance in finished goods.

What Does Isocyclocitral Smell Like?

Perfumers place Isocyclocitral in the green family because its scent immediately calls to mind fresh plant matter. Off a blotter it opens with a vivid impression of crushed leaves and snapped stems, almost as if you had brushed past a tomato vine in a sun-warmed garden. The note is sharp yet airy, carrying a leafy brightness rather than an earthy heaviness, and it stays remarkably clear as the minutes pass.

When discussing how a material behaves in a formula we often break the evaporation curve into top, middle and base notes. Top notes are the first to reach the nose, middle notes form the heart of the perfume once the top has lifted and base notes linger longest on skin or fabric. Isocyclocitral falls squarely in the top to early-middle zone. It announces itself quickly, delivering a fresh green accent, then gently fades to let other ingredients take over.

The projection is strong at first, so only a small amount is needed to achieve lift in a blend. Longevity is moderate: expect the green tone to remain noticeable on a blotter for one to two hours before it subsides. In a full composition a well-judged dose can extend that freshness slightly, especially when paired with supporting materials that slow its evaporation.

How & Where To Use Isocyclocitral

Most perfumers agree this is a pleasant ingredient to handle. It pours easily, blends without fuss and its odour profile is clear enough to judge within seconds of dilution.

In a formula Isocyclocitral acts as a razor sharp green accent. A touch brightens herbal, galbanum or violet leaf accords and keeps citrus openings feeling freshly cut rather than sugary. It is especially handy when a composition needs the snap of a tomato leaf nuance but without the sulphuric edge of some natural extracts.

Reach for it instead of cis-3-hexenol when you want less grass and more leafy stem. It also partners well with mint, basil and ozonic materials, helping them read as dewy garden rather than candy. In florals a trace can lift lily of the valley or muguet accords, giving them a crunchy petal texture.

Typical usage sits anywhere from 0.05 % for a subtle lift up to 2 % in boldly green concepts. Above that the note can become piercing and almost chemical so moderation is wise. At very low levels the molecule adds freshness without being identifiable while higher percentages bring a distinct tomato vine character.

Performance in functional products is solid. It survives most detergent bases, keeps its green bite through hot candle pours and stays stable in soap. The flash-point of 71 °C means it handles gentle heating but avoid prolonged high-heat processing to prevent loss of brightness.

No special prep is usually required. If you plan extended evaluation in water-based testers first premix the ingredient into ethanol or dipropylene glycol, as it is insoluble in water. Otherwise weigh, dilute, evaluate.

Safety Information

As with all concentrated aroma chemicals certain precautions and considerations need to be followed when working with Isocyclocitral.

  • Always dilute before smelling: prepare a 10 % or lower solution in a suitable solvent before evaluation
  • Do not sniff straight from the bottle: this avoids overwhelming the nose and accidental inhalation of high vapour levels
  • Ensure good ventilation: work in a lab with extraction or at least an open window and avoid building up vapour in closed spaces
  • Wear gloves and safety glasses: protect skin and eyes from splashes and potential irritation
  • Health considerations: some individuals may experience skin irritation or allergic response, consult a medical professional before use if pregnant or breastfeeding and remember that brief low-level exposure is generally safe while prolonged or high-level exposure can be harmful

Always consult the latest safety data sheet supplied by your vendor and review it regularly as information can change. Follow current IFRA guidelines for maximum inclusion levels in finished products to ensure responsible and safe formulation.

Storage And Disposal

When stored with care Isocyclocitral usually keeps its full strength for about two to three years, sometimes longer. Check the supplier’s recommended retest date and run a quick smell test every six months to confirm it is still fresh.

Refrigeration is helpful but not essential. A cool dark cupboard away from direct sunlight heaters and windows works for most labs. Steady temperature is more important than low temperature so avoid shelves that warm up during the day then cool at night.

Use bottles that seal tightly. Polycone caps give a snug fit and limit air exchange far better than glass dropper tops which often let vapour leak and oxygen creep in. Top up your working bottle whenever the level drops below two thirds so less air sits above the liquid reducing the risk of gradual oxidation.

Keep concentrates in amber or aluminium containers, store dilutions in high quality PET or glass and wipe any spills from threads before closing. Label everything with the material name batch date dilution strength and hazard symbols so anyone picking it up knows exactly what it is.

For disposal follow local regulations. Small test strips and tiny rinse amounts can usually go in normal lab waste. Larger liquid leftovers should be collected in a sealed drum and handed to a licensed chemical disposal service. While the molecule is expected to biodegrade over time it can still harm aquatic life in concentrated form so avoid pouring neat material down the drain.

Rinse empty bottles with a little solvent before recycling, let the solvent evaporate under a fume hood then recycle or discard the clean container as allowed in your area.

Summary

Isocyclocitral is a lab made green note that smells like freshly crushed leaves and tomato vine. It adds an instant burst of natural greenery to citrus openings herbal mixes floral stems and even some fresh marine ideas. Because the scent lands between top and early heart it gives lift without hanging around too long which keeps blends feeling lively.

Perfumers enjoy it because it is affordable easy to blend and keeps its colour and punch in soaps detergents fine fragrance and candles. The main watch points are its strong diffusive power, the need for cool dark storage and avoiding overuse that can skew a formula toward chemical sharpness.

If you want a quick way to sharpen a galbanum accord brighten muguet or replace part of cis-3-hexenol give this molecule a try. It is a fun tool in the green palette and one you will likely reach for again and again once you hear that first clean leafy pop off the blotter.

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