Isolaureth-4 Phosphate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Isolaureth-4 Phosphate?

Isolaureth-4 Phosphate is a surfactant made by joining fatty alcohol from coconut or palm oil with a short chain of ethylene oxide, then attaching phosphoric acid. The result is a gentle salt-like material that mixes well with both oil and water. First introduced in the late 1970s when brands wanted milder cleansers, it has since become a go-to helper in wash-off and leave-on products.

Manufacturers create it in three main steps: they take the plant-based fatty alcohol, add four units of ethylene oxide to improve water solubility, then treat that blend with phosphoric acid to form the final phosphate ester. After neutralizing and filtering, the ingredient is ready for use.

You will most often see Isolaureth-4 Phosphate in facial cleansers, shower gels, micellar waters, shampoo, makeup removers, light lotions and serums that need a bit of cleansing power without stripping the skin.

Isolaureth-4 Phosphate’s Cosmetic Benefits/Uses

Formulators pick Isolaureth-4 Phosphate for two main jobs

  • Cleansing – lifts away dirt, excess oil and makeup while staying mild so the skin’s natural moisture barrier stays intact
  • Emulsifying – helps oil and water blend into a stable mix, giving products a smooth feel and keeping them from separating on the shelf

Who Can Use Isolaureth-4 Phosphate

This ingredient is gentle enough for most skin types, including dry, oily, combination and sensitive skin, because it cleans without stripping away too much natural oil. Those with very compromised or eczema-prone skin might still prefer richer, soap-free cleansers to minimize potential dryness.

Isolaureth-4 Phosphate is typically made from coconut or palm-derived fatty alcohol and phosphoric acid so it is suitable for both vegans and vegetarians. Always confirm that the finished product has not been animal-tested if cruelty-free status is important to you.

No data suggest that the ingredient poses a special risk during pregnancy or while breastfeeding and very little, if any, is expected to absorb through intact skin. This is not medical advice; anyone who is pregnant or nursing should ask a doctor before starting a new skincare product just to be safe.

The molecule does not make skin more sensitive to sunlight and there are no known interactions with common actives such as retinoids or acids. It is also fragrance-free by itself which can be helpful for people trying to avoid added scent.

Potential Side Effects/Adverse Reactions

Reactions to topical Isolaureth-4 Phosphate can vary from person to person. The points below outline potential issues yet they are unlikely for the average user when the ingredient is properly formulated and used as directed.

  • Mild skin dryness may occur if the product is left on too long or used too frequently, especially in low humidity climates
  • Transient stinging or tingling can happen on very sensitive or damaged skin
  • Eye irritation if the cleanser accidentally gets into the eyes
  • Allergic contact dermatitis is rare but possible in individuals who develop a specific sensitivity to the molecule

If you experience any unwanted reaction discontinue use and consult a healthcare professional.

Comedogenic Rating

Rating: 1/5 (low)

Isolaureth-4 Phosphate is highly water soluble and either rinses off completely or remains at very small amounts in leave-on products. Because it does not create a heavy film and disperses readily in water the chance of it settling into pores is minimal.

This low rating means it is generally a safe choice for people who struggle with acne or frequent breakouts.

Remember that the pore-clogging potential of any finished product also depends on the other ingredients in the formula and how thoroughly it is removed at the end of the day.

Summary

Isolaureth-4 Phosphate works as both a cleanser and an emulsifier. By lowering surface tension it lifts away dirt and oil then keeps water and oil evenly mixed so products stay smooth and stable.

You will find it in gentle face washes, micellar waters, shampoos and lightweight lotions. It is popular with formulators looking for mild alternatives yet it remains a behind-the-scenes helper rather than a headline ingredient for shoppers.

Decades of safe use and supporting data show a low risk of irritation or pore clogging. Still, skin can be unpredictable so it is wise to perform a quick patch test when trying any new product that contains this ingredient.

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