Isopropylidenediphenol Bishydroxypropyl Peg-180: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Isopropylidenediphenol Bishydroxypropyl Peg-180?

Isopropylidenediphenol Bishydroxypropyl Peg-180 is a synthetic polymer created by linking bisphenol A derivatives with long chains of ethylene oxide units. In simpler terms, chemists start with bisphenol A, react it with propylene oxide to give hydroxypropyl groups, then attach an average of 180 ethylene oxide molecules. The result is a large water-loving molecule that behaves much like a flexible net, able to grab on to other ingredients and hold them in place.

The ingredient was first investigated in the late 1980s when formulators were searching for gentler alternatives to traditional thickening resins. Its ability to improve texture without adding heaviness made it an attractive option for skin care labs. Over time it found a niche in modern cosmetics that aim for lightweight, fast-absorbing formulas.

Production takes place in controlled reactors where temperature and pH are carefully monitored. After each reaction step, the mixture is purified to remove unreacted monomers and small by-products, then tested for purity before being drummed or bagged for shipment to cosmetic manufacturers.

You will most often see Isopropylidenediphenol Bishydroxypropyl Peg-180 in sheet masks, gel moisturizers, anti-aging serums, cleansing balms, hair conditioning treatments and makeup primers where a smooth spread and stable texture are key.

Isopropylidenediphenol Bishydroxypropyl Peg-180’s Cosmetic Benefits/Uses

Formulators choose this polymer mainly for its binding ability, which offers several practical perks in everyday products.

As a binder it holds water, oils and active ingredients together so a formula stays uniform from the first use to the last. This keeps pigments from separating in a primer, prevents actives from settling at the bottom of a serum and helps creamy textures resist flaking or cracking once applied to skin or hair. The end user experiences a product that feels smooth, spreads evenly and maintains performance over time.

Who Can Use Isopropylidenediphenol Bishydroxypropyl Peg-180

This ingredient is considered gentle enough for most skin types. Its water-attracting structure supports light, non-greasy formulas that suit oily, combination and normal skin, while its ability to lock in moisture can also help dry skin stay comfortable. Sensitive skin usually tolerates it well because it is non-ionic and free of harsh solvents, though anyone with a known sensitivity to PEGs should remain cautious.

The polymer is fully synthetic and produced without animal-derived materials so it is generally suitable for vegans and vegetarians. Manufacturers typically certify the supply chain to confirm no animal testing or by-products are involved.

No research shows specific risks for pregnant or breastfeeding women when this polymer is applied topically. The molecule is large, sits on the skin’s surface and is unlikely to absorb systemically, yet this is not medical advice. Anyone who is pregnant or nursing should review any skincare product with a qualified healthcare professional to be safe.

Isopropylidenediphenol Bishydroxypropyl Peg-180 does not increase photosensitivity and has no known impact on sun tolerance, so normal sun protection practices are sufficient.

Potential Side Effects/Adverse Reactions

Responses to topical Isopropylidenediphenol Bishydroxypropyl Peg-180 vary from person to person. The effects listed below are uncommon and most users experience none of them when the ingredient is used correctly in a finished product.

  • Mild skin irritation such as transient redness or a stinging sensation, usually in people already sensitive to PEG compounds
  • Allergic contact dermatitis presenting as rash or itching in rare cases
  • Eye irritation or watering if the product accidentally enters the eyes before it sets
  • Increased penetration of other active ingredients, which could amplify their irritation potential

If any adverse reaction occurs stop using the product and seek guidance from a healthcare professional.

Comedogenic Rating

Rating: 0-1 on the 0-5 scale.

This polymer is highly water soluble and forms a light film that lets skin breathe rather than blocking pores. Its large size keeps it on the surface and it is not oily, so it has little to no chance of trapping sebum or dead cells. For these reasons it sits at the very low end of the comedogenic scale.

Suitable for acne-prone or breakout-prone skin.

One thing to note: in rich creams packed with heavy oils or waxes the overall formula, not this polymer, could still feel greasy and potentially clogging.

Summary

Isopropylidenediphenol Bishydroxypropyl Peg-180 is mainly a binder that keeps water, oils and actives evenly mixed so the product stays smooth from jar to skin. Its long, flexible, water-loving chains grab hold of different ingredients, reduce separation and give formulas a silky glide without extra weight.

It is not a household name like hyaluronic acid or glycerin, yet it shows up quietly in many modern gels, masks and primers because it solves texture problems at low doses.

Overall safety is high: the molecule is large, non-ionic and unlikely to penetrate skin. Irritation and allergy are rare and mostly linked to people who are already sensitive to PEGs. As with any new cosmetic, a small patch test is a smart step when you try a product that lists this ingredient.

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