Isostearamidopropyl Morpholine Lactate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Isostearamidopropyl Morpholine Lactate?

Isostearamidopropyl Morpholine Lactate is a specialty conditioning agent made by combining isostearic acid, a fatty acid usually derived from vegetable oils, with morpholine and lactic acid. The result is a mild, water-compatible compound that carries a positive charge. This positive charge helps it cling to the negatively charged surface of hair and skin. The ingredient first appeared in salon hair care during the late 1990s as chemists searched for plant-based alternatives to traditional quaternary ammonium salts. Production involves reacting isostearic acid with a small molecule called N-(3-aminopropyl)morpholine to form an amide, then neutralizing the mixture with lactic acid to create a stable salt. Today you will most often find Isostearamidopropyl Morpholine Lactate in rinse-off conditioners, leave-in sprays, anti-frizz serums, detangling creams, and some beard balms.

Isostearamidopropyl Morpholine Lactate’s Cosmetic Benefits/Uses

This ingredient is used mainly for its antistatic action. By depositing a thin, positively charged layer on hair fibers it reduces static buildup, which helps keep flyaways in check, makes combing easier and leaves hair looking smoother and more controlled.

Who Can Use Isostearamidopropyl Morpholine Lactate

This conditioning agent suits most hair and skin types including dry, normal and oily because it is lightweight and usually rinses clean. People with very sensitive or allergy-prone skin should still check the full product formula since irritation is more often caused by accompanying fragrances or preservatives than by this ingredient itself.

Isostearic acid used in commercial production usually comes from plant oils, so the finished compound is considered vegan and vegetarian friendly. No animal-derived materials are typically involved during manufacturing.

Pregnant or breastfeeding individuals are not known to face any special risk from topical use of Isostearamidopropyl Morpholine Lactate at the low levels found in cosmetics. This is general information only and not medical advice. Those who are expecting or nursing should show the product to their healthcare provider before adding it to a routine.

The ingredient does not make skin more sensitive to sunlight and there is no evidence it interferes with sunscreen performance. It is also fragrance-free and nonvolatile, so it will not add scent or evaporate from the skin.

Potential Side Effects/Adverse Reactions

Reactions to topical Isostearamidopropyl Morpholine Lactate differ from person to person. The effects listed below are possible yet uncommon when the ingredient is used at the concentrations allowed in cosmetic products.

  • Mild skin redness or stinging in individuals with highly reactive skin
  • Eye irritation if the product accidentally gets into the eyes before rinsing
  • Allergic contact dermatitis in the rare case of a true allergy to the molecule
  • Build-up and limp feel on very fine hair when a leave-in formula is overapplied

If any persistent irritation or other unwanted reaction occurs stop using the product and seek advice from a qualified healthcare professional.

Comedogenic Rating

Rating: 1 out of 5. Isostearamidopropyl Morpholine Lactate is largely water compatible and forms a very thin, easily removable film so it is unlikely to block pores for most users. Its fatty portion is highly branched which limits the ingredient’s ability to pack tightly inside follicles. Because of this low likelihood of clogging, it is generally considered suitable for acne-prone or breakout-prone skin. Only individuals who react to almost any conditioning agent might need to watch for congestion when using rich leave-in formulas.

Summary

Isostearamidopropyl Morpholine Lactate is a plant-derived conditioning agent that fights static by laying a positively charged layer over hair and skin. This thin coating smooths cuticles, tames flyaways and makes combing easier with minimal weight. Although it does its job well it remains a niche ingredient, seen mainly in higher-end conditioners, beard balms and detanglers rather than mass-market shampoos.

Current safety data show a low risk of irritation or allergy when used at normal cosmetic levels, and it carries a very low comedogenic rating. As with any new personal care product it is smart to perform a quick patch test before full use, especially for those with sensitive or reactive skin.

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