Isostearamidopropyl Pg-Dimonium Chloride: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Isostearamidopropyl Pg-Dimonium Chloride?

Isostearamidopropyl Pg-Dimonium Chloride is a quaternary ammonium compound made from isostearic acid, a fatty acid usually sourced from plant oils such as coconut or soybean. Chemically, it carries a positive charge that lets it cling to the negatively charged surface of hair and some fabrics, which is why it is often classed as a cationic surfactant. Quats like this one entered the cosmetic scene in the middle of the twentieth century when formulators were searching for ways to tame static in early synthetic fabrics and later discovered the same effect was helpful on hair. This particular molecule was designed to be softer on skin and hair while still offering strong conditioning. Manufacturing starts with isostearic acid that is reacted with a small amine, then quaternized in the presence of propylene glycol to lock in its permanent positive charge, after which it is purified and standardized for cosmetic use.

You will most often spot Isostearamidopropyl Pg-Dimonium Chloride in rinse-off and leave-in conditioners, hair masks, anti-frizz creams, 2-in-1 shampoos and occasionally in rich body lotions or cream cleansers where its antistatic effect can improve skin feel.

Isostearamidopropyl Pg-Dimonium Chloride’s Cosmetic Benefits/Uses

This ingredient is included in formulas because it provides two main benefits

  • Antistatic: forms a thin, positively charged layer that neutralizes the static charge building up on hair strands, which cuts down on flyaways and frizz and makes hair easier to style
  • Hair conditioning: deposits a conditioning film that smooths the cuticle, boosts softness and shine and improves slip so combs glide through wet or dry hair with fewer snags

Who Can Use Isostearamidopropyl Pg-Dimonium Chloride

This quaternary conditioner is generally compatible with all skin and hair types, including dry, normal, combination and oily. Its mild nature means it is usually well tolerated even by sensitive scalps, though anyone with a history of reactions to cationic conditioners should proceed carefully.

The molecule is manufactured from plant derived isostearic acid so it is normally suitable for vegans and vegetarians. As always, it is wise to check that the finished product is certified cruelty free and that no animal derived processing aids were used by the supplier.

Current safety data shows no specific risks for pregnant or breastfeeding women because the ingredient stays on the hair surface and is not meaningfully absorbed through intact skin. This is informational only and not medical advice; anyone who is expecting or nursing should show the product to a healthcare professional before regular use just to be safe.

Isostearamidopropyl Pg-Dimonium Chloride does not make skin or hair more sensitive to sunlight so there is no added risk of photosensitivity. It can be used on colored or chemically treated hair without stripping dye or disrupting curl patterns.

Potential Side Effects/Adverse Reactions

Reactions to topical use of Isostearamidopropyl Pg-Dimonium Chloride differ from person to person. The points below outline potential issues that could occur, although they are uncommon when the ingredient is used at typical cosmetic levels.

  • Mild scalp or skin irritation such as itching or redness
  • Allergic contact dermatitis in individuals already sensitized to quaternary ammonium compounds
  • Eye irritation if the product accidentally gets into the eyes
  • Product buildup that can leave hair feeling heavy or greasy when overused
  • Reduced foaming or cleansing power if layered directly with highly anionic shampoos, potentially leading to a coated feel

If any uncomfortable reaction occurs, discontinue use and seek guidance from a medical professional or dermatologist.

Comedogenic Rating

Rating: 1 / 5. Although the molecule contains a fatty tail, its quaternary ammonium head makes it water dispersible and far less likely to clog pores than straight plant oils or waxes. In most rinse-off and leave-in hair products the concentration is low and it stays mostly on the hair shaft, further reducing pore-blocking potential.

Given this low score, Isostearamidopropyl Pg-Dimonium Chloride is generally considered suitable for people prone to acne or breakouts.

Because the ingredient is cationic it can interact with anionic cleansers, sometimes leaving a light film on skin if not rinsed completely, but this is rarely enough to trigger acne.

Summary

Isostearamidopropyl Pg-Dimonium Chloride is a quaternary conditioner that cuts static and smooths hair by depositing a thin positively charged layer that binds to the negatively charged cuticle. The same film boosts softness, shine and comb-through slip, making it a handy multi-tasker in conditioners, masks and anti-frizz creams.

It is not the most talked-about ingredient in beauty circles but formulators appreciate its gentle feel and reliable performance, so it shows up in many mid-priced and salon products even if it rarely gets star billing on the label.

Current safety data classifies it as low risk for irritation or sensitization at typical use levels, with minimal chance of clogging pores or being absorbed through skin. Still, every skin is unique so it is wise to patch test any new product that contains this conditioner before using it all over.

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