Isosteareth-12: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Isosteareth-12?

Isosteareth-12 is a synthetic fatty alcohol made by attaching about 12 units of ethylene oxide to isostearyl alcohol, which in turn usually comes from isostearic acid found in vegetable oils such as soybean or rapeseed. The result is a waxy, off-white substance that dissolves in both water and oil, making it a useful bridge between the two. Chemists started adding ethylene oxide to fatty alcohols in the 1950s to improve the feel and stability of creams and lotions, and Isosteareth-12 quickly found a place in personal care formulas that needed a gentle but effective helper ingredient. Today it is produced in large batches through controlled ethoxylation, then purified and blended into ready-to-use pellets or pastes. You will most often spot it on the label of facial cleansers, lightweight moisturizers, clay or sheet masks, anti-aging serums, makeup removers, hair conditioners and even some sunscreens where it helps keep the formula smooth and uniform.

Isosteareth-12’s Cosmetic Benefits/Uses

Formulators reach for Isosteareth-12 because it wears more than one hat in a product.

  • Cleansing: The ingredient loosens dirt, oil and leftover makeup so they rinse away easily, helping cleansers leave skin feeling fresh without a squeaky or tight after-feel
  • Emulsifying: By holding water and oil together it prevents creams and lotions from separating, giving products a stable texture and a pleasant glide while also improving the delivery of active ingredients

Who Can Use Isosteareth-12

Most skin types tolerate Isosteareth-12 well. Its mild cleansing action makes it suitable for normal, oily and combination skin while its low residue profile means it usually will not weigh down acne-prone skin. Sensitive skin generally does fine with it, though anyone with a history of reactions to ethoxylated ingredients should proceed carefully. Extremely dry or compromised skin might prefer richer fatty alcohols because Isosteareth-12 on its own does not add much moisture.

The ingredient is typically considered vegan and vegetarian friendly because it is produced from plant-derived isostearic acid and petrochemical ethylene oxide, not from animal sources. Still, supply chains can vary so strict vegans may wish to confirm a brand’s sourcing policy.

Current safety data show no known risks for pregnant or breastfeeding women when the ingredient is used topically at the low levels found in cosmetics. This is not medical advice and anyone who is pregnant or nursing should run any skincare products past a qualified doctor just to be safe.

Isosteareth-12 does not cause photosensitivity and has no known interactions with sunlight. It is also scent-free, making it a handy option for those avoiding fragrance allergens.

Potential Side Effects/Adverse Reactions

Side effects from topical Isosteareth-12 can vary from person to person. The following points list potential reactions, but they are uncommon when the ingredient is formulated and used correctly.

  • Mild skin irritation such as redness or itching, especially on very sensitive skin
  • Contact dermatitis triggered by an allergy to ethoxylated surfactants
  • Transient eye stinging if a cleanser containing the ingredient gets into the eyes
  • Dryness or a tight feeling when used in high-foaming formulas without added moisturizers
  • Folliculitis or small pimples in rare cases where the formula is overly occlusive

If any of these issues occur discontinue use and consult a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 1/5

Isosteareth-12 is a lightweight, water-soluble fatty alcohol that does not leave much residue on skin, so it is unlikely to clog pores. Its cleansing and emulsifying roles help lift oils away rather than sit on top of the skin, keeping the risk of buildup low. Because it is usually used at modest levels and rinses off easily in cleanser formats, most dermatology references list it on the lower end of the comedogenic scale.

In short, Isosteareth-12 is generally suitable for people prone to acne or breakouts. Only those with extremely reactive or congested skin might notice issues, and that is more often due to the entire formula than this single ingredient.

One extra note: comedogenicity can rise slightly if the ingredient is paired with heavy occlusives in very rich creams, so context within the overall product still matters.

Summary

Isosteareth-12 works as a gentle cleanser and a reliable emulsifier. It loosens dirt and excess oil so they rinse away clean, while its ability to bond water and oil stops lotions and creams from separating and keeps textures smooth.

Although it is not a headline act like retinol or vitamin C, formulators like it because it is dependable, versatile and cost-effective. You will find it quietly doing its job in a wide range of mainstream skincare and haircare launches, especially in milky cleansers and lightweight moisturizers.

Current safety data show low irritation potential, no hormonal concerns and no phototoxicity. Most users can apply products containing Isosteareth-12 with confidence, but as with any new skincare ingredient it is smart to patch test to rule out personal sensitivities.

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