Isosteareth-25: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Isosteareth-25?

Isosteareth-25 is the cosmetic name for polyoxyethylene (25) isostearyl ether, a substance made by linking about twenty-five ethylene oxide units to a fatty alcohol called isostearyl alcohol. The fatty alcohol usually comes from plant-derived oils such as coconut or rapeseed, which are refined and split to isolate the alcohol portion before the ethylene oxide is added. This process creates a water-loving head and an oil-loving tail, giving the ingredient its well-known surfactant and emulsifier abilities.

Its roots trace back to the mid-20th century, when chemists searched for gentler cleansers that could blend oil and water without leaving a heavy film. Over time, Isosteareth-25 proved useful in both rinse-off and leave-on formulas thanks to its balance of mildness and performance. Today you can spot it in facial cleansers, micellar waters, makeup removers, light lotions, hair conditioners, sheet masks and even some anti-aging serums that need a smooth, stable texture.

Isosteareth-25’s Cosmetic Benefits/Uses

In skin and hair care products Isosteareth-25 performs two main jobs that make formulas work better and feel nicer.

  • Cleansing: Its surfactant nature traps dirt, oil and leftover makeup so they rinse away easily, giving a fresh clean feel without harsh stripping
  • Emulsifying: It helps mix oil and water into a uniform blend, keeping creams, lotions or serums from separating while also giving them a silky, spreadable texture

Who Can Use Isosteareth-25

Because it is a mild nonionic surfactant, Isosteareth-25 generally suits most skin types, including normal, oily, combination and even sensitive skin that struggles with stronger foaming agents. Dry or very compromised skin might notice a slight tight feel if the product contains a high level of the ingredient but in most well-balanced formulas this is rarely an issue.

The raw material is synthesized from plant-derived fatty alcohols and petroleum-free ethylene oxide, and no animal by-products are involved during standard manufacturing. For that reason products using Isosteareth-25 are typically acceptable for vegetarians and vegans, although it is always wise to check the rest of the ingredient list for hidden animal sources.

No studies have flagged Isosteareth-25 as a concern for women who are pregnant or breastfeeding when used topically. It is classed as non-teratogenic and non-mutagenic at the concentrations used in cosmetics. That said this is not medical advice and anyone who is expecting or nursing should ask their doctor before adding new skincare just to stay on the safe side.

The ingredient does not make skin more sensitive to sunlight and it does not interfere with sunscreen filters, so there is no added risk of sunburn or pigmentation when you use it during the day.

Potential Side Effects/Adverse Reactions

Reactions to topical Isosteareth-25 differ from one person to the next. The points below list potential issues only and most people will never run into them when the ingredient appears at the low levels common in finished products.

  • Skin irritation – a mild stinging or burning sensation can occur on very reactive skin, especially if formulas contain high surfactant loads
  • Allergic contact dermatitis – rare cases of redness itching and small bumps may show up in users with specific sensitivities to ethoxylated ingredients
  • Eye irritation – if a cleanser that contains Isosteareth-25 gets into the eyes it can cause temporary watering or discomfort
  • Dryness or tightness – over-cleansing or long contact times may strip natural oils leaving the skin feeling parched

If you notice any of the above while using a product that contains Isosteareth-25 stop use immediately and consult a healthcare professional if symptoms persist or worsen.

Comedogenic Rating

Rating: 1/5

Isosteareth-25 is a large, water-soluble molecule that does not easily penetrate follicles or form a heavy film on the skin. Its job is mainly to help oils mix with water then rinse away, so it is far less likely than fatty oils or waxes to clog pores. Because most formulas use it at low levels for cleansing or emulsifying, buildup on the skin is minimal.

Suitable for acne-prone or breakout-prone skin in both rinse-off and well-balanced leave-on products.

As with any surfactant, pairing it with overly rich occlusive ingredients could raise the clogging risk a bit, though that depends more on the overall formula than on Isosteareth-25 itself.

Summary

Isosteareth-25 works as a mild cleanser and an effective emulsifier. Its water-loving polyethylene chain grabs onto water while the fatty isostearyl tail attaches to oils, letting it lift grime and disperse oily ingredients evenly through lotions, serums and cleansers.

The ingredient pops up in a fair number of modern skincare and haircare products but it is not as famous as older classics like sodium lauryl sulfate or polysorbates. Brands choose it when they need a gentler touch or a light, silky feel.

Safety data shows low irritation potential, no known reproductive risks and a very low comedogenic rating. Still, skin can be unpredictable so it is always smart to patch test any new product that contains Isosteareth-25 before full use.

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