What Is Kojyl Carboxy Sh-Oligopeptide-75 Amide?
Kojyl Carboxy Sh-Oligopeptide-75 Amide is a lab-crafted short chain of amino acids that has been linked to a modified form of kojic acid, a well-known brightening agent naturally found in some fungi. By attaching kojic acid to a peptide backbone and adding extra carboxy groups, chemists created a molecule that stays stable on the skin yet breaks down slowly to release its benefits. The amide ending helps keep the peptide from breaking apart too soon, giving formulas a longer shelf life.
The ingredient grew out of early 2000s research aimed at pairing gentle peptides with skin-loving actives. Scientists first looked at it for spot-lightening products, then found its antioxidant power also helped protect skin from daily stress. Today it is made through solid-phase peptide synthesis, where amino acids are added one by one to a resin bead, followed by attachment of the kojic acid unit and a final amidation step. The finished powder is filtered, purified and freeze-dried before heading to cosmetic labs.
You will most often see Kojyl Carboxy Sh-Oligopeptide-75 Amide in targeted serums, brightening creams, sheet masks, eye treatments and high-end anti-aging moisturizers. Because it works well at low levels, it is also included in lightweight lotions and fluid sunscreens that focus on tone and texture support.
Kojyl Carboxy Sh-Oligopeptide-75 Amide’s Cosmetic Benefits/Uses
This multitasking peptide brings several helpful actions to skin care formulas:
- Antioxidant: Helps neutralize free radicals formed by sunlight and pollution which can otherwise lead to dullness and early signs of aging. Adding it to a product can boost the overall protective shield of the formula.
- Skin conditioning: Supports a smoother, softer feel by supplying small amino acids that draw in moisture. Regular use can leave skin looking more even and feeling supple.
- Skin protecting: Forms a light defensive film on the surface that works with other actives to guard against external stressors such as dirt, smoke and harsh weather. This makes the ingredient a good partner in day creams and urban defense products.
Who Can Use Kojyl Carboxy Sh-Oligopeptide-75 Amide
Kojyl Carboxy Sh-Oligopeptide-75 Amide is generally suitable for all skin types, including oily, dry, combination and mature skin. Its lightweight, water-soluble nature means it rarely feels heavy or greasy, which makes it friendly for acne-prone or congestion-prone complexions. People with very sensitive or reactive skin can usually tolerate it, thanks to its gentle peptide backbone, though they should still introduce it gradually in case their skin is easily irritated by new actives.
The ingredient is produced through synthetic peptide chemistry with no animal-derived materials, so it fits vegan and vegetarian standards.
Current research shows no specific risks for pregnant or breastfeeding women when the ingredient is used topically in the small amounts found in cosmetics. This is not medical advice, so anyone expecting or nursing should confirm product choices with a qualified healthcare provider before use, just to be safe.
Unlike some brightening agents, Kojyl Carboxy Sh-Oligopeptide-75 Amide does not heighten the skin’s sensitivity to sunlight, so it is not considered photosensitizing. Daily sunscreen is still important, but no extra precautions are needed solely because of this peptide.
Potential Side Effects/Adverse Reactions
Reactions to topical Kojyl Carboxy Sh-Oligopeptide-75 Amide vary from person to person. The issues listed below are possible but uncommon when the ingredient is formulated and used correctly.
- Mild redness or warmth – a temporary flush that settles once the product is removed
- Itchiness – usually short-lived but can occur if skin is already compromised or overly dry
- Stinging around the eyes or on broken skin – more likely if applied too close to the lash line or on open blemishes
- Contact dermatitis – rare allergic reaction that shows up as persistent redness, bumps or flaking
- Ingredient clash with strong exfoliants – layering with high-percentage acids or retinoids can occasionally increase irritation potential
If any of these effects appear and do not calm quickly after rinsing, stop using the product and consult a healthcare professional for guidance.
Comedogenic Rating
Rating: 0 / 5
Kojyl Carboxy Sh-Oligopeptide-75 Amide is a water-soluble peptide that does not leave an oily residue on the skin and has no known tendency to block pores, so it earns the lowest possible score. Its large molecular size keeps it on the skin’s surface instead of seeping into sebaceous ducts where clogs form. This makes it a safe choice for people who are prone to acne or breakouts.
As with any ingredient, the final product’s full formula and texture can affect pore-clogging potential, so pay attention to the overall product type if congestion is a concern.
Summary
Kojyl Carboxy Sh-Oligopeptide-75 Amide acts as an antioxidant, skin conditioner and skin protector. The kojic acid segment helps quench free radicals while the peptide chain draws water to the skin and supports a smoother feel. Extra carboxy groups let it form a sheer protective film that shields against daily environmental stress.
The ingredient is still considered niche and appears mainly in high-end serums, masks and creams rather than mass-market ranges, but formulators value it for multitasking benefits at low use levels.
Current data shows it is well tolerated with a low risk of irritation or pore blockage, making it a generally safe addition to most routines. As with any new skincare product, perform a quick patch test first to be sure your skin agrees.