Lactamide Mea: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Lactamide Mea?

Lactamide Mea, formally called N-2-hydroxyethyllactamide, is an amide formed when naturally sourced lactic acid is reacted with monoethanolamine. The lactic acid usually comes from the fermentation of plant sugars such as corn or beet while monoethanolamine is a well-known pH-adjusting agent made from ethylene oxide and ammonia. The reaction links the two molecules into a small water-loving compound that carries both hydroxyl and amide groups, features that let it grab onto moisture and smooth surfaces.

Chemists began experimenting with Lactamide Mea in the late 1970s when the cosmetics industry was searching for humectants that felt lighter than glycerin but gentler than propylene glycol. Its ability to soften hair without weighing it down quickly attracted formulators, and it has since found a steady place in both haircare and skincare lines.

Commercial production is straightforward: lactic acid and monoethanolamine are blended under controlled heat, water produced during the reaction is removed, and the resulting Lactamide Mea is filtered and sometimes spray-dried into a free-flowing powder. Because the raw materials are widely available and the process is mild, the ingredient is considered cost-effective and eco-friendly.

You will most often see Lactamide Mea in leave-in conditioners, rinse-off conditioners, anti-frizz serums, moisturizing shampoos, face masks, light lotions, hand creams and aftershave balms. Its compatibility with both water-based and some alcohol-based systems lets it slot into everything from mist toners to richer night creams.

Lactamide Mea’s Cosmetic Benefits/Uses

Here is how Lactamide Mea works once it is blended into a formula

  • Antistatic: By neutralizing electrical charges on the surface of hair fibers it helps stop flyaways and makes hair easier to comb and style
  • Hair conditioning: Its small size lets it penetrate the cuticle slightly depositing moisture and leaving strands feeling softer smoother and more manageable
  • Humectant: The molecule attracts and binds water from the environment which boosts the overall hydration level of a product keeping both hair and skin from feeling dry or tight
  • Skin conditioning: On skin it forms a light flexible film that improves suppleness gives a soft touch finish and can enhance the spreadability of other actives in the formula

Who Can Use Lactamide Mea

Lactamide Mea is generally suitable for all skin and hair types thanks to its light hydrating profile. Dry or dehydrated skin will appreciate its humectant boost while oily and combination types can benefit from the extra moisture without a greasy after-feel. Very sensitive or eczema-prone skin should proceed with a bit more caution because any amide can theoretically trigger irritation in a small subset of users though reported cases are rare.

The ingredient is vegan and vegetarian friendly because the lactic acid is sourced from fermented plant sugars and monoethanolamine is produced synthetically from petro-based feedstocks, so no animal-derived substances are involved in its manufacture.

Current safety data suggest that Lactamide Mea poses no specific risk to pregnant or breastfeeding women when used topically in normal cosmetic concentrations, but this is not medical advice. Anyone who is pregnant or nursing should show the full ingredient list of any product to their healthcare provider for personalized guidance.

Lactamide Mea is not known to increase photosensitivity and can be used in both day and night formulas without requiring extra sun precautions beyond a standard broad-spectrum sunscreen.

Potential Side Effects/Adverse Reactions

Individual responses to topical Lactamide Mea can vary. The points below cover potential but uncommon reactions assuming the product has been formulated and preserved correctly and is being used as directed.

  • Skin irritation – mild redness itching or a burning sensation on particularly reactive skin
  • Allergic contact dermatitis – rare sensitization presenting as a rash or swelling
  • Eye irritation – stinging or watering if the product accidentally gets into the eyes
  • Scalp buildup – very heavy or frequent applications on fine hair might lead to limp strands or a weighed-down feel
  • Interaction with highly cationic actives – in exceptional cases formula incompatibility could lead to precipitation which may reduce product performance

If any discomfort or visible reaction develops stop using the product and consult a healthcare professional for assessment and care advice.

Comedogenic Rating

Rating: 1 out of 5. Lactamide Mea is highly water soluble and has a low molecular weight, which means it rinses away easily and does not sit in pores long enough to block them. It lacks heavy oils or waxy side chains that typically trigger congestion, so it is considered very low risk for clogging pores. Therefore it is generally suitable for people prone to acne or breakouts. Only in very rich formulations partnered with occlusive butters could its presence indirectly contribute to pore blockage.

Summary

Lactamide Mea works as a humectant, skin conditioner, hair conditioner and antistatic helper. Its hydroxyl and amide groups pull in water, its light film smooths cuticles and skin, and its slight charge balances static on hair. While not a headline ingredient like hyaluronic acid or niacinamide, it enjoys steady use in leave-in conditioners, hydrating shampoos, face masks and lightweight lotions because it is affordable and easy to formulate with. Safety studies show it is non-sensitizing for most users and has very low comedogenic potential. As with any new cosmetic ingredient it is smart to patch test a product containing Lactamide Mea before full use.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search