Lactobacillus/Wine Stillage Ferment: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Lactobacillus/Wine Stillage Ferment?

Lactobacillus/Wine Stillage Ferment comes from the fermentation of wine stillage, which is the leftover mix of grape skins, seeds and pulp that remains after wine is pressed. When the friendly bacterium Lactobacillus is introduced to this stillage it digests the plant material and releases a blend of amino acids, antioxidants and organic acids. The result is a fluid rich in nourishing compounds that help support the skin’s natural barrier.

Fermentation processes like this have been used for centuries in food and beverages, but their cosmetic use grew in the past decade as brands looked for greener ways to create active ingredients. By converting winemaking by-products into a skin loving ferment, manufacturers reduce waste while gaining a botanical extract with proven benefits.

The production method is straightforward: collected wine stillage is sterilized, inoculated with selected Lactobacillus strains then allowed to ferment under controlled temperature and pH until the desired activity is reached. After filtration and stabilization the ferment is ready to add to formulas.

You will usually find Lactobacillus/Wine Stillage Ferment in lightweight moisturizers, soothing masks, anti-aging serums and daily lotions designed to boost skin resilience.

Lactobacillus/Wine Stillage Ferment’s Cosmetic Benefits/Uses

This ingredient is valued for one key role in skincare formulations.

As a skin protecting agent Lactobacillus/Wine Stillage Ferment helps reinforce the skin’s natural barrier. Its mix of antioxidants and mild acids supports the microbiome, limits moisture loss and shields the surface from daily stress like pollution and temperature changes. Products containing this ferment often leave skin feeling calmer, better hydrated and more resilient over time.

Who Can Use Lactobacillus/Wine Stillage Ferment

This ferment is generally suitable for all skin types, including dry, oily, combination and sensitive. Its gentle nature and barrier-supporting properties make it especially helpful for skin that is easily dehydrated or prone to redness. There are no known reasons for people with acne-prone or mature skin to avoid it, as it is lightweight and non-greasy.

The ingredient is derived from plant material fermented with bacteria, so it is appropriate for both vegans and vegetarians. No animal-derived substances are involved in the manufacturing process.

Pregnant and breastfeeding women can typically use products containing Lactobacillus/Wine Stillage Ferment, since it is applied only to the skin and has no reported hormonal activity. That said this is not medical advice and anyone who is pregnant or nursing should discuss new skincare products with a healthcare professional to be extra safe.

Lactobacillus/Wine Stillage Ferment does not increase the skin’s sensitivity to sunlight, so it is not considered photosensitising. Standard daytime sun protection is still recommended for overall skin health.

Potential Side Effects/Adverse Reactions

Reactions to topical Lactobacillus/Wine Stillage Ferment differ from person to person. The effects listed below are possible yet uncommon when the ingredient is formulated correctly.

  • Mild redness or stinging for a few minutes after application, usually subsides quickly
  • Itching or a tight sensation in very sensitive skin
  • Contact dermatitis in individuals allergic to any component of the ferment or the finished formula
  • Temporary breakouts if the overall product is too rich for oily skin

If you notice any discomfort that persists or worsens stop using the product and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 0 / 5

Lactobacillus/Wine Stillage Ferment is an aqueous ferment filtrate with virtually no heavy oils or waxes, so it does not linger in pores or form occlusive layers that could trap debris. Its molecules are mostly water soluble antioxidants, peptides and mild acids that rinse away cleanly. As a result it shows no tendency to clog pores in standard cosmetic concentrations.

Suitable for acne-prone or breakout-prone skin.

The final product formula matters more than the ferment itself. If it is blended with rich butters or comedogenic oils, the overall product could still trigger congestion.

Summary

Lactobacillus/Wine Stillage Ferment functions primarily as a skin protecting agent. Through its mix of antioxidant compounds, gentle acids and microbiome friendly peptides it reinforces the skin barrier, reduces transepidermal water loss and helps defend against daily environmental stress.

While not a headline ingredient in every brand, its upcycled origin and gentle performance are gaining attention as consumers look for sustainable actives. You will mainly spot it in moisturizers, soothing masks and light serums aimed at boosting resilience.

Topical use is considered very safe with few reported issues. As with any new skincare, perform a quick patch test when you first try a product containing this ferment to ensure your skin agrees with it.

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