Lactuca Virosa Leaf Extract: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Lactuca Virosa Leaf Extract?

Lactuca Virosa Leaf Extract comes from the leaves of poison lettuce, a wild relative of the garden lettuce that belongs to the daisy family. The leaves are naturally rich in sesquiterpene lactones, flavonoids and polysaccharides, molecules that help the plant protect itself from stress in its environment. Herbal records dating back to the 19th century note the plant’s use in soothing balms, and modern formulators have taken interest in its calming qualities for the skin. To create the extract, harvested leaves are cleaned, dried and then soaked in a solvent such as water or a mix of water and gentle alcohol. The liquid is filtered and concentrated, yielding a clear to amber fluid that can be blended easily into creams or serums. You will most often spot Lactuca Virosa Leaf Extract in hydrating moisturizers, calming masks, anti-aging lotions and after-sun gels where a comforting feel is desired.

Lactuca Virosa Leaf Extract’s Cosmetic Benefits/Uses

This extract is prized for its role as a skin conditioning agent. In a finished formula it helps soften and smooth the skin surface, supports a healthy moisture balance and leaves the complexion feeling calm and refreshed.

Who Can Use Lactuca Virosa Leaf Extract

This leaf extract is gentle enough for most skin types. Normal, dry and combination skin often find it soothing while sensitive skin may appreciate its calming touch. Oily or breakout-prone skin can also use it since the extract is light and not known to clog pores. Because it is taken only from a plant source it is suitable for both vegans and vegetarians, with no animal-derived additives involved in its production.

There is no specific evidence that the ingredient poses a risk to women who are pregnant or breastfeeding when applied topically, yet formal studies are lacking. This is not medical advice and anyone who is pregnant or nursing should run any skincare routine past a healthcare professional first, just to stay on the safe side.

Lactuca Virosa Leaf Extract is not known to cause photosensitivity, so daytime use does not require extra precautions beyond your usual sunscreen. It also plays well with most common skincare actives, so layering it with vitamin C, niacinamide or gentle exfoliating acids is generally problem-free.

Potential Side Effects/Adverse Reactions

Responses to topical Lactuca Virosa Leaf Extract vary from person to person. The points below list potential side effects only and most users will not experience them when the ingredient has been properly formulated in a finished product.

  • Allergic contact dermatitis in individuals sensitive to plants from the daisy family
  • Mild redness or itching on very reactive skin
  • Temporary stinging if applied to broken or freshly exfoliated skin
  • Rare cross-reaction with other botanical extracts that share similar compounds

If any of these effects occur stop using the product and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 1 out of 5. Lactuca Virosa Leaf Extract is mainly a water-soluble blend of plant molecules with very little oil or wax, so it is unlikely to clog pores. It sits light on the skin, absorbs quickly and is typically used at low concentrations, all of which keep its pore-blocking potential minimal. This makes it generally suitable for people who are prone to acne or breakouts. If the finished product also contains heavy oils, butters or silicones, those ingredients, not the extract, are the ones more likely to cause congestion.

Summary

Lactuca Virosa Leaf Extract conditions the skin by delivering calming flavonoids, soothing polysaccharides and protective antioxidants that help soften, smooth and maintain healthy moisture. Although it is not a headline ingredient like hyaluronic acid or retinol, it is gaining quiet popularity in niche soothing formulas thanks to its gentle nature and plant-based story. Overall safety is high when used topically, with only rare reactions in people sensitive to the daisy family. As with any new skincare ingredient it is wise to patch test a fresh product on a small area first, just to confirm personal compatibility.

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