Laureth-21: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Laureth-21?

Laureth-21 is a synthetic ingredient made by attaching an average of 21 units of ethylene oxide to lauryl alcohol, a fatty alcohol usually sourced from coconut or palm kernel oil. The result is a clear to slightly hazy liquid that dissolves in water and mixes well with oils, giving it strong surface-active properties. Chemists began using ethoxylated fatty alcohols in the 1950s when the cosmetics industry was looking for gentler alternatives to soap-based cleansers. Because it offered reliable foam, good rinse-off and mildness on skin, Laureth-21 quickly became a standard helper surfactant in personal care labs.

Manufacturing starts with plant-derived lauryl alcohol, which reacts with ethylene oxide gas under controlled heat and pressure. The reaction is stopped once the average chain reaches 21 oxyethylene units, then the mixture is purified and quality tested before it is sold to formulators.

Today Laureth-21 shows up in many rinse-off and leave-on products including facial cleansers, body washes, shampoos, micellar waters, exfoliating masks, makeup removers, hand soaps, bubble baths, light lotions and some cream bases where extra cleansing or rinseability is desired.

Laureth-21’s Cosmetic Benefits/Uses

In formulas Laureth-21 serves one main purpose that brings several practical benefits.

Cleansing: It lowers the surface tension between water and oils so dirt, sweat and makeup lift away more easily during rinsing. It boosts foam, helps other surfactants spread more evenly on skin or hair and leaves a clean yet non-stripped feel, making products gentler and more effective.

Who Can Use Laureth-21

Because Laureth-21 is classified as a mild cleansing agent it is generally suitable for normal, oily and combination skin. Those with very dry or highly reactive skin might find frequent use of rinse-off formulas slightly drying if the product is not balanced with moisturizers, so look for hydrating ingredients alongside it.

The ingredient is synthesized from plant-derived fatty alcohol and petroleum-free ethylene oxide so it is considered vegan and vegetarian friendly. No animal by-products are needed at any stage of production.

Current safety reviews show no added risks for women who are pregnant or breastfeeding when Laureth-21 is used in cosmetic concentrations. That said, this is not medical advice and anyone expecting or nursing should ask a health professional before adding new personal care products.

Laureth-21 is not known to cause photosensitivity, meaning it will not make skin more prone to sunburn. It also plays well with common actives like acids, retinoids and vitamin C, so there are no special timing rules when layering products.

Potential Side Effects/Adverse Reactions

Responses to topical Laureth-21 can differ from person to person. The points below list potential side effects that have been reported in rare cases. When the ingredient is used at the levels typically found in cosmetics most people will not experience these issues.

  • Mild skin irritation such as redness or stinging
  • Dryness or tightness if used in high amounts or in very frequent wash cycles
  • Contact dermatitis in individuals with existing allergies to ethoxylated surfactants
  • Eye irritation if the product accidentally gets into the eyes

If any of these reactions occur stop using the product and consult a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 1/5

Laureth-21 is highly water soluble and rinses away without leaving an oily film on skin, so it has very little tendency to clog pores. The single point is given only because any surfactant can cause minor barrier disruption if overused, which might indirectly aggravate breakout-prone skin.

Because of this low score Laureth-21 is generally considered suitable for people who are prone to acne or frequent breakouts.

No reliable data suggest the ingredient feeds acne-causing bacteria or traps sebum, and it is not listed as a common trigger in comedogenicity studies.

Summary

Laureth-21 is primarily a cleansing and foaming helper that works by lowering surface tension so water can lift away oils dirt and makeup. Thanks to its 21 ethylene oxide units it is both water loving and oil loving, allowing it to sit at the interface and create a stable, easy-to-rinse lather.

The ingredient shows up in a wide range of everyday products from face washes to bubble baths, making it a familiar staple in many labs even if it rarely gets star billing on the front label.

Current safety reviews conclude Laureth-21 is low-risk at cosmetic levels, with only mild irritation possible in sensitive users. As with any new product it is smart to run a quick patch test first to make sure your skin stays comfortable.

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