Lauroyl Polyneopentyl Glycol Adipate Phthalte/Pei-45 Crosspolymer: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Lauroyl Polyneopentyl Glycol Adipate Phthalte/Pei-45 Crosspolymer?

Lauroyl Polyneopentyl Glycol Adipate Phthalte/PEI-45 Crosspolymer is a synthetic polymer created by linking together several building blocks found in nature and in the lab. Chemists start with lauroyl polyneopentyl glycol adipate, a fatty-acid based ester that offers a lightweight, silky feel. They react it with phthalic acid to give the molecule added backbone, then attach PEI-45, a branched polyethyleneimine that brings multiple connection points. A final reaction with lauric acid helps cap and stabilize the structure. The result is a large, mesh-like molecule that behaves a bit like a flexible net dispersed in a formula.

The ingredient was first explored in the early 2000s when formulators needed a way to stabilize the new wave of water-light serums without relying on heavy waxes or high levels of gums. Its ability to fine-tune thickness while leaving a soft, non-greasy finish quickly earned it a place in premium skincare labs. Today it appears in facial moisturizers, hydrating serums, sheet mask essences, sunscreens, color cosmetics like liquid foundations and even in some hair-styling creams to give a smooth glide.

Production happens in specialized facilities that handle multi-step polymer reactions. Each stage is carefully temperature-controlled to ensure the long chains grow in a uniform way. After purification the polymer looks like an off-white pellet or viscous liquid that dissolves easily into oils and certain solvents used in cosmetic manufacturing.

Lauroyl Polyneopentyl Glycol Adipate Phthalte/Pei-45 Crosspolymer’s Cosmetic Benefits/Uses

This ingredient is prized mainly for one job inside a formula.

Viscosity controlling: By sitting between oil and water phases the polymer can either thicken a runny lotion or lighten a heavy cream, giving chemists precise control over texture. It helps keep pigments and actives evenly suspended so the product looks smooth when squeezed from the tube and feels elegant on the skin. Stable viscosity also means fewer chances of separation during storage which extends shelf life and maintains a premium user experience.

Who Can Use Lauroyl Polyneopentyl Glycol Adipate Phthalte/Pei-45 Crosspolymer

This texture-tuning polymer is considered gentle enough for most skin types including dry, normal, combination and oily skin because it does not add heavy oils or strong actives that could tip the skin’s balance. Sensitive skin usually tolerates it as well since the molecule stays on the surface and is chemically stable, though highly reactive or compromised skin should still approach new formulas with caution.

The ingredient is made entirely from synthetic or plant-derived building blocks so it is suitable for vegans and vegetarians. No animal materials or animal testing are required for its manufacture in regions that follow standard cosmetic regulations.

Current safety data show no specific risks for women who are pregnant or breastfeeding when the polymer is used at the low levels found in cosmetics. This is not medical advice and anyone who is expecting or nursing should ask a doctor before introducing new skincare products just to be safe.

The molecule does not make skin more sensitive to sunlight and has no known impact on photosensitivity treatments such as laser or chemical peels. It is also odorless and free of common fragrance allergens, making it a useful choice in fragrance-free or hypoallergenic lines.

Potential Side Effects/Adverse Reactions

Individual responses to topical Lauroyl Polyneopentyl Glycol Adipate Phthalte/PEI-45 Crosspolymer can differ. The points below outline potential side effects but most people will not notice any problems when the ingredient is used within accepted cosmetic limits.

  • Mild transient skin redness or stinging
  • Localized irritation in people with very sensitive or broken skin barriers
  • Rare allergic contact dermatitis resulting in itching or small bumps
  • Watery eyes or slight eye irritation if a product accidentally gets into the eyes

If you notice persistent discomfort stop using the product and seek advice from a healthcare professional

Comedogenic Rating

Rating: 1/5. Lauroyl Polyneopentyl Glycol Adipate Phthalte/PEI-45 Crosspolymer is a large, branched molecule that stays mostly on the skin’s surface and has minimal oiliness. Its fatty building blocks are locked inside a high-molecular-weight network, so they cannot clog pores the way free oils sometimes do. Formulas generally use it at low percentages which further limits any pore-blocking risk.

Because of this low rating it is usually fine for acne-prone or breakout-prone skin, provided the rest of the formula is also non-comedogenic.

As with many texture agents its final impact depends on the other ingredients in a product, so always consider the full ingredient list when choosing skincare for congested skin.

Summary

Lauroyl Polyneopentyl Glycol Adipate Phthalte/PEI-45 Crosspolymer acts mainly as a viscosity controller. Its flexible polymer network slips between water and oil droplets to fine-tune thickness, keep pigments and actives evenly dispersed and prevent separation during storage. The result is a smooth, elegant texture that feels lightweight on the skin.

While not a household name, the ingredient has a solid following among formulators who want a modern alternative to gums or heavy waxes. You are most likely to find it in mid- to high-end lotions, serums, sunscreens and liquid makeup where a silky finish matters.

Current data show it is low risk for irritation or pore clogging when used at standard cosmetic levels. Still, skin can be unpredictable so it is wise to patch test any new product that contains this polymer before applying it more broadly.

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