What Is Luteolin?
Luteolin is a naturally occurring plant pigment classed as a flavonoid, scientifically named 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-benzopyrone. It is abundant in many herbs and vegetables such as parsley, celery and chamomile. Chemically, it features four hydroxyl groups that give it strong antioxidant properties, making it appealing for skin care. Traditional herbal remedies have long relied on luteolin-rich plants for soothing purposes, and modern cosmetic science picked up on these benefits during the late 20th century when researchers began isolating pure luteolin to study its effect on skin.
Commercially, luteolin is produced by extracting it from plant sources or by gentle chemical synthesis that mirrors the structure found in nature. The extraction route usually involves water or food-grade solvents followed by purification steps to yield a fine yellow powder that blends easily with creams, serums and gels.
You will most often find luteolin in soothing masks, daily moisturizers, after-sun lotions, anti-aging serums and targeted treatments for sensitive or redness-prone skin. Its compatibility with both water-based and oil-based formulas lets product developers slot it into a wide range of textures from lightweight essences to richer night creams.
Luteolin’s Cosmetic Benefits/Uses
In topical products luteolin serves a single yet valuable purpose
Skin conditioning: Luteolin helps maintain a soft, smooth feel on the skin by supporting the natural barrier and supplying antioxidant activity. This can translate to calmer looking skin, a more even tone and an overall comfortable sensation after application
Who Can Use LuteolinLuteolin is generally considered suitable for all skin types including dry, oily, sensitive and combination because it is lightweight, non comedogenic and mainly acts as a soothing antioxidant. Those with extremely reactive or allergy prone skin should still approach any new ingredient with caution, especially if they have known sensitivities to flavonoid rich plants such as chamomile or celery.
The ingredient is naturally sourced from plants or produced through plant identical synthesis so it is appropriate for vegans and vegetarians. No animal derived substances are involved in its standard production process.
Current literature shows no specific risks linked to topical luteolin during pregnancy or breastfeeding. Still, this is not medical advice and pregnant or nursing individuals should discuss any skincare product with their physician to be safe.
Luteolin does not increase photosensitivity. In fact its antioxidant activity may help buffer the effects of UV exposure, though it is never a replacement for sunscreen. There are no known interactions with common skincare actives, which lets it pair well with moisturizers, retinoids or gentle exfoliants.
Potential Side Effects/Adverse Reactions
Reactions to topical luteolin can vary from person to person. The following list covers potential side effects that could occur, though most users will not experience them when the ingredient is formulated and used correctly.
- Mild stinging or burning sensation on application
- Transient redness or flushing in very sensitive skin
- Allergic contact dermatitis in individuals with flavonoid allergies
- Yellowish staining of light fabrics if a high concentration product is not fully absorbed
- Rare interaction with highly acidic formulas that may reduce antioxidant stability
If any irritation or unexpected reaction occurs stop using the product immediately and consult a healthcare professional or dermatologist.
Comedogenic Rating
Rating: 0/5
Luteolin is a lightweight water- and alcohol-soluble flavonoid with no oily or waxy residues that could clog pores. It does not sit on the skin’s surface like heavier emollients so it earns a solid zero on the comedogenic scale.
That means it is generally suitable for people who are prone to acne or breakouts.
Formulators often pair luteolin with non-comedogenic carriers such as aloe juice or glycerin which helps keep the overall product breakout-friendly. Of course the final formula’s pore-clogging risk depends on every ingredient in the mix, not just luteolin.
Summary
Luteolin’s main job in skincare is skin conditioning. It does this by donating electrons to neutralize free radicals, calming surface irritation and helping the skin barrier stay comfortable and smooth. These antioxidant and soothing properties can translate to a more even tone and softer feel.
Compared with headline actives like vitamin C or niacinamide, luteolin is less of a household name yet formulators value it for its gentle touch and plant-derived appeal. You will usually see it in products aimed at sensitive, redness-prone or post-sun skin.
Overall safety is high with very few reports of adverse reactions. Still everyone’s skin is unique so it is smart to patch test any new product that contains luteolin before applying it over larger areas.