Magnesium Lithospermate B: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Magnesium Lithospermate B?

Magnesium lithospermate B is a plant-derived compound that comes from the roots of Salvia miltiorrhiza, also known as red sage or danshen. In nature the plant makes a group of strong antioxidants called lithospermic acids. When lithospermic acid B is combined with magnesium ions it forms the stable salt used in cosmetics. The result is a reddish brown powder that dissolves well in water-based formulas.

Researchers first looked at this molecule in the mid-1990s for its ability to fight free radicals. Skin-care chemists soon noticed that the same protective action could help keep skin and hair looking healthy, so suppliers began to refine extraction methods for cosmetic use. Today the ingredient is produced by soaking dried red sage roots in a water-alcohol mix, filtering out unwanted plant matter then purifying the extract with food-grade solvents. The purified acid is reacted with magnesium salts under controlled pH, dried and milled into a fine powder that is easy to blend.

You will most often see magnesium lithospermate B in antioxidant serums, anti-aging creams, after-sun gels, soothing sheet masks, hydrating toners, leave-in hair conditioners and scalp treatments where an extra boost of antioxidant and antimicrobial support is wanted.

Magnesium Lithospermate B’s Cosmetic Benefits/Uses

When added to a formula this multitasker offers several helpful actions:

  • Antimicrobial: Helps curb the growth of odor-causing and breakout-causing microbes so products stay fresh longer and skin stays clearer
  • Antioxidant: Neutralizes free radicals created by UV light and pollution which can speed up visible aging such as dullness and fine lines
  • Hair Conditioning: Coats the hair shaft with a light film that smooths rough spots reduces static and improves shine
  • Humectant: Attracts and holds water on the surface of skin and hair giving a plumper softer feel
  • Skin Protecting: Forms a gentle barrier that helps defend skin from everyday irritants and supports a healthy moisture balance

Who Can Use Magnesium Lithospermate B

Most people find magnesium lithospermate B gentle enough for daily use. Its humectant and antioxidant actions make it friendly to dry and mature skin while the light antimicrobial support helps oily and breakout-prone types. Sensitive skin also tends to tolerate it because the molecule is non-acidic and non-exfoliating. The main group who may need caution are individuals with known allergies to the mint family of plants, which includes red sage; they should first confirm with a healthcare professional before use.

The ingredient is sourced from plant roots and no animal-derived substances are involved in the extraction or purification steps, so it is considered suitable for vegans and vegetarians.

No published data link topical magnesium lithospermate B to problems in pregnancy or breastfeeding. Still, this is not medical advice and anyone who is pregnant or nursing should show the full product ingredient list to their doctor before adding it to a routine, just to be safe.

Unlike some botanical extracts it does not make skin more sensitive to sunlight, so it is not classed as photosensitising. Standard daytime sun protection is still recommended.

Potential Side Effects/Adverse Reactions

Responses to any cosmetic ingredient can vary from person to person. The points below list potential but uncommon side effects linked to topical use of magnesium lithospermate B when it is included at normal cosmetic levels. In properly formulated products most users will not notice any of these issues.

  • Mild irritation slight stinging or tightness on first application, usually subsides quickly
  • Redness temporary flushing in very reactive skin types especially if combined with other strong actives
  • Contact allergy rare cases of itching or rash in people allergic to red sage or related plants
  • Discoloration the natural reddish tint of the powder can cause a faint temporary stain on very light fabrics or towels

If any unwanted reaction occurs stop using the product and seek advice from a qualified healthcare professional.

Comedogenic Rating

Rating: 0 / 5

Magnesium lithospermate B is a small water-soluble molecule that does not form an occlusive film or leave oily residues on skin. It is typically used at low concentrations and is quickly absorbed or rinsed away, which keeps pore-clogging risk very low.

Suitable for acne-prone and breakout-prone skin.

Keep in mind that the finished product formula and other ingredients, such as heavy oils or waxes, can still influence how pore-friendly a product feels overall.

Summary

Magnesium lithospermate B brings five key actions to personal care: it scavenges free radicals to guard against premature aging, curbs certain microbes that can upset skin balance, draws moisture to the surface for a plumper feel, lightly coats hair for smoothness and shine, and adds a protective buffer that helps skin hold on to water. It does all this while staying gentle because it is non-acidic and water-based.

Although not a household name like vitamin C or hyaluronic acid, this red sage extract is popping up more often in targeted serums, soothing masks and scalp treatments as formulators look for plant-powered multitaskers.

Current research and user experience suggest it is very safe with only rare reports of mild irritation or allergy, mostly in people sensitive to the mint family of plants. As with any new product it is wise to perform a quick patch test before applying it to larger areas.

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