MartiDerm sits in that sweet spot where dermatologists nod approvingly and beauty aficionados wonder how they have skipped past its brown glass ampoules for so long. The Spanish brand has a reputation for pragmatic, science first formulas that still feel a touch luxe, and Night Renew Ampoules carry that flag proudly.
The name itself reads like a bedtime story for skin, promising a fresh chapter by sunrise. According to MartiDerm, this overnight treatment uses a soft peeling blend of alpha hydroxy acids to nudge off dull surface cells while marine collagen and hyaluronic acid lock in moisture, support firmness and smooth fine lines. The concept is simple: slip the tiny vial into your evening routine, wake up looking a little more polished, then let your other night products ride the momentum.
I spent a solid two weeks cracking open these miniature chem labs, following the brand’s shake click and pour ritual to the letter. My goal was to pin down whether the glow they promise is worth your hard earned cash or if the ampoules should stay in the laboratory.
Disclaimer: this review is not paid or sponsored. The opinions below are entirely my own based on personal experience and individual results can vary from one complexion to another.
What Is Night Renew Ampoules?
Night Renew Ampoules sit in the overnight treatment category, a corner of skincare designed to work while the skin is in its natural repair cycle during sleep. Products in this group tend to deliver higher concentrations of actives than daytime formulas because they do not have to fight makeup or sunscreen layers, and they avoid sun sensitivity issues that can come with ingredients like acids.
Here the active blend is built around alpha hydroxy acids, a family of exfoliants that loosen the bonds holding dead surface cells. Glycolic, lactic and mandelic acids headline the list, each chosen for its ability to smooth texture and brighten tone with minimal irritation when timed for night use. Supporting that mild peel are marine collagen and hyaluronic acid, two humectants that pull water into the outer layers of skin helping offset the dryness that acids can trigger. Together the mix aims to nudge cell turnover, replenish lost moisture and give a subtle firming effect by encouraging fresh collagen and elastin.
The product is pre portioned inside single use glass ampoules. You crack one open, dispense half the liquid across face neck and chest, then seal the rest for the following night. The idea is to maintain potency by limiting the formula’s contact with air and light while also guiding you toward a controlled dose so you do not overload the skin.
Did It Work?
In the spirit of rigorous bathroom science I benched my usual overnight serum for three nights before starting the ampoules, a sacrifice that felt noble enough to qualify for a tiny lab coat. Fourteen days feels like a fair window to spot meaningful changes so I stuck to the instructions: half an ampoule on cleansed skin, then a bland moisturizer on top to seal everything in.
Night one delivered the classic AHA tingle, a whisper of warmth that faded after a minute. I woke up with skin that felt smooth to the touch, not dramatically brighter but definitely more refined than the night before. By night three the tingling had downgraded to a slight buzz which told me my barrier was adjusting.
The midpoint check at day seven showed the most visible progress. My forehead looked a shade more even, and a rough patch along my jawline had lost its sandpaper attitude. I did notice a faint tightness around my nose by late afternoon, easily fixed with an extra dab of moisturizer. No flaking, no angry patches, just a reminder that acids still demand respect.
In the final stretch I chased consistency. Each ampoule emptied cleanly, the liquid staying clear and fresh thanks to the single use glass. By day fourteen the overall picture was: smoother texture, a modest lift in luminosity and pores that appeared a hair less obvious under harsh office lighting. Fine lines around my eyes and mouth looked about the same, and any firming effect was subtle enough that only I could spot it in an unforgiving magnifying mirror.
So did it work? Yes, within reason. Night Renew delivered gentle exfoliation without drama, and it left my skin feeling comfortably hydrated which is no small feat for an acid blend. Still, the changes were incremental rather than transformative. I would happily finish the box but I will likely return to my usual cocktail of retinoid plus hydrating serum once the last ampoule clicks into the trash. If your skin craves a low irritation glow kick this is a solid option but it does not earn a permanent slot on my shelf.
Night Renew Ampoules’s Main Ingredients Explained
The exfoliating clout of Night Renew hinges on a quartet of alpha hydroxy acids. Glycolic acid, the smallest molecule in the family, slips deepest to break up dull surface bonds which helps soften fine lines over time. Lactic acid follows close behind offering a gentler sweep that simultaneously tops up hydration thanks to its water-binding nature. Mandelic and malic acids round out the peel cocktail, both sitting higher on the molecular scale so they work at a slower pace that reduces sting while refining pores and tone.
Moisture support comes from hyaluronic acid, the ingredient everyone wants at the party because it can hold up to one-thousand times its weight in water. It sits on and just beneath the stratum corneum pulling ambient moisture toward the skin so the fresh layer revealed by the acids does not feel stripped. Marine collagen offers a cushioning film that traps that hydration while giving a temporary plumping effect. Worth noting for ethical shoppers: marine collagen is sourced from fish so the formula is neither vegan nor vegetarian friendly.
None of the listed actives rank high on the comedogenic scale which rates how likely an ingredient is to clog pores, though any leave-on acid does increase skin turnover and can briefly push impurities to the surface. If you are very prone to breakouts pair the ampoules with a light non-occlusive moisturizer and watch for congestion around the nose and chin in the first week.
As for pregnancy, AHAs in concentration under 10 percent are generally viewed as low risk yet dermatologists still advise caution. Hormonal skin can behave unpredictably so expectant users should run the ingredient list past their doctor before cracking open an ampoule.
The preservative-free glass packaging keeps the acids stable and reduces the need for added fragrance, though there is a faint sour note typical of AHAs that fades fast. Overall the ingredient line up is concise, smartly dosed and free of alcohol or drying surfactants which explains why the formula feels unexpectedly calming for an exfoliating product.
What I Liked/Didn’t Like
Here is the straightforward rundown after two weeks of nightly use.
What Works Well:
- Convenient single dose glass ampoules keep the acids potent and hygienic
- Gentle exfoliation delivers smoother texture with very little sting or redness
- Humectant base leaves skin comfortably hydrated so it pairs easily with a plain night cream
- Plays nicely with other actives making it a low-drama addition to an existing routine
What to Consider:
- Glass vials feel a bit fiddly and you can lose a drop or two while swapping caps
- Results are subtle so thrill seekers may crave something stronger or longer term
- Marine collagen comes from fish which rules it out for vegan or vegetarian users
My Final Thoughts
Night Renew Ampoules sit comfortably in the solid but not life changing camp. They are the sort of overnight treatment you reach for when your skin is crying out for a reset yet you are not ready to brave prescription level acids or retinoids. The formula behaved well, the glass delivery system felt clinical in a fun way and the mild brightening was undeniable, but the promised firming was more “maybe I see it in certain lighting” than the collagen rebirth suggested by the marketing copy. After two weeks of faithful use I am giving it a respectable 7/10. I would recommend it to friends with normal to slightly dry skin who want a gentle polish without risking flakes or fury. If you are chasing dramatic wrinkle reduction or heavy duty pigmentation work you will likely find it a well mannered appetizer rather than the main course.
For anyone shopping the night treatment aisle, variety is plentiful and I have had hands on time with plenty of worthy contenders. Nocturnal Revive Cream by Deascal is the one I toss at almost every skin type because it covers hydration barrier support and a touch of brightening at an unbeatable price. If you prefer a pillowy gel texture that floods thirsty skin LANEIGE Water Sleeping Mask has never let me down. Texture junkies who lean oily and want stronger resurfacing power might enjoy Drunk Elephant’s T.L.C. Framboos Glycolic Night Serum while chronically dry or sensitised complexions often breathe a sigh of relief with First Aid Beauty’s Ultra Repair Hydra-Firm Night Cream. Each of these has earned a repeat spot in my rotation for different reasons so you can match the mood of your skin rather than wed yourself to one formula forever.
Before you crack any of these open remember the basics: patch test on a discreet area for a couple of nights, build up frequency slowly and keep a plain moisturiser on standby. Apologies for sounding like an over-protective parent but irritation is never chic. Lastly, glowing results only last as long as you keep up the routine so stock up or be ready to return to square one.